Acyl carrier protein (PA2966)

Identification
Name: Acyl carrier protein
Synonyms:
  • ACP
  • Cytosolic-activating factor
  • CAF
  • Fatty acid synthase acyl carrier protein
Gene Name: acpP
Enzyme Class: Not Available
Biological Properties
General Function: Involved in fatty acid biosynthetic process
Specific Function: Carrier of the growing fatty acid chain in fatty acid biosynthesis
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Complex Reactions:
(R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]+Thumb ↔ acyl carrier protein+Thumb
(R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + Uridine diphosphate-N-acetylglucosamine ↔ acyl carrier protein + UDP-3-O-(3-Hydroxymyristoyl)-N-acetylglucosamine
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Dodecanoyl-ACP (n-C12:0ACP)+Thumb+Thumb → acyl carrier protein+Thumb
Dodecanoyl-ACP (n-C12:0ACP) + Hydrogen ion + Phosphate → acyl carrier protein + Dodecanoly-phosphate (n-C12:0)
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Thumb+cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)+Thumb → acyl carrier protein+Thumb
Hydrogen ion + cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1) + Phosphate → acyl carrier protein + Octadecanoyl-phosphate (n-C18:1)
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Thumb+Myristoyl-ACP (n-C14:0ACP)+Thumb → acyl carrier protein+Thumb
Hydrogen ion + Myristoyl-ACP (n-C14:0ACP) + Phosphate → acyl carrier protein + Tetradecanoyl-phosphate (n-C14:0)
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Thumb+Octadecanoyl-ACP (n-C18:0ACP)+Thumb → acyl carrier protein+Thumb
Hydrogen ion + Octadecanoyl-ACP (n-C18:0ACP) + Phosphate → acyl carrier protein + Octadecanoyl-phosphate (n-C18:0)
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Thumb+Palmitoyl-ACP (n-C16:0ACP)+Thumb → acyl carrier protein+Thumb
Hydrogen ion + Palmitoyl-ACP (n-C16:0ACP) + Phosphate → acyl carrier protein + Hexadecanoyl-phosphate (n-C16:0)
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acyl carrier protein+Thumb ↔ Acetyl-ACP+Thumb
acyl carrier protein + Acetyl-CoA ↔ Acetyl-ACP + Coenzyme A
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acyl carrier protein+Thumb ↔ Thumb+Malonyl-[acyl-carrier protein]
acyl carrier protein + Malonyl-CoA ↔ Coenzyme A + Malonyl-[acyl-carrier protein]
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Dodecanoyl-ACP (n-C12:0ACP)+Thumb → Thumb+acyl carrier protein
Dodecanoyl-ACP (n-C12:0ACP) + Glycerol 3-phosphate → 1-Dodecanoyl-sn-glycerol 3-phosphate + acyl carrier protein
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Thumb+cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1) → Thumb+acyl carrier protein
Glycerol 3-phosphate + cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1) → 1-Hexadec-9-enoyl-sn-glycerol 3-phosphate + acyl carrier protein
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Thumb+cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1) → Thumb+acyl carrier protein
Glycerol 3-phosphate + cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1) → 1-Octadec-11-enoyl-sn-glycerol 3-phosphate + acyl carrier protein
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Thumb+cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1) → Thumb+acyl carrier protein
Glycerol 3-phosphate + cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1) → 1-Tetradec-7-enoyl-sn-glycerol 3-phosphate + acyl carrier protein
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Thumb+Myristoyl-ACP (n-C14:0ACP) → Thumb+acyl carrier protein
Glycerol 3-phosphate + Myristoyl-ACP (n-C14:0ACP) → 1-Tetradecanoyl-sn-glycerol 3-phosphate + acyl carrier protein
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Thumb+Octadecanoyl-ACP (n-C18:0ACP) → Thumb+acyl carrier protein
Glycerol 3-phosphate + Octadecanoyl-ACP (n-C18:0ACP) → 1-Octadecanoyl-sn-glycerol 3-phosphate + acyl carrier protein
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Thumb+Palmitoyl-ACP (n-C16:0ACP) → Thumb+acyl carrier protein
Glycerol 3-phosphate + Palmitoyl-ACP (n-C16:0ACP) → 1-hexadecanoyl-sn-glycerol 3-phosphate + acyl carrier protein
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acyl carrier protein+Thumb+Thumb → Thumb+Palmitoyl-ACP (n-C16:0ACP)+Thumb
acyl carrier protein + Adenosine triphosphate + Palmitic acid → Adenosine monophosphate + Palmitoyl-ACP (n-C16:0ACP) + Pyrophosphate
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acyl carrier protein+Thumb+Thumb → Thumb+Octanoyl-ACP (n-C8:0ACP)+Thumb
acyl carrier protein + Adenosine triphosphate + Caprylic acid → Adenosine monophosphate + Octanoyl-ACP (n-C8:0ACP) + Pyrophosphate
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acyl carrier protein+Thumb+Thumb → Thumb+Decanoyl-ACP (n-C10:0ACP)+Thumb
acyl carrier protein + Adenosine triphosphate + Decanoate (N-C10:0) → Adenosine monophosphate + Decanoyl-ACP (n-C10:0ACP) + Pyrophosphate
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acyl carrier protein+Thumb+Thumb → Thumb+Dodecanoyl-ACP (n-C12:0ACP)+Thumb
acyl carrier protein + Adenosine triphosphate + Dodecanoate (N-C12:0) → Adenosine monophosphate + Dodecanoyl-ACP (n-C12:0ACP) + Pyrophosphate
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acyl carrier protein+Thumb+Thumb → Thumb+Octadecanoyl-ACP (n-C18:0ACP)+Thumb
acyl carrier protein + Adenosine triphosphate + Octadecanoate (N-C18:0) → Adenosine monophosphate + Octadecanoyl-ACP (n-C18:0ACP) + Pyrophosphate
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acyl carrier protein+Thumb+Thumb → Thumb+cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)+Thumb
acyl carrier protein + Adenosine triphosphate + Octadecenoate (N-C18:1) → Adenosine monophosphate + cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1) + Pyrophosphate
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acyl carrier protein+Thumb+Thumb → Thumb+Myristoyl-ACP (n-C14:0ACP)+Thumb
acyl carrier protein + Adenosine triphosphate + tetradecanoate (n-C14:0) → Adenosine monophosphate + Myristoyl-ACP (n-C14:0ACP) + Pyrophosphate
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acyl carrier protein+Thumb+Thumb → Thumb+Thumb+cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
acyl carrier protein + Adenosine triphosphate + Tetradecenoate (N-C14:1) → Adenosine monophosphate + Pyrophosphate + cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0015361-Dodecanoyl-sn-glycerol 3-phosphateMetaboCard
PAMDB0015371-Hexadec-9-enoyl-sn-glycerol 3-phosphateMetaboCard
PAMDB0015381-hexadecanoyl-sn-glycerol 3-phosphateMetaboCard
PAMDB0015391-Octadec-11-enoyl-sn-glycerol 3-phosphateMetaboCard
PAMDB0015401-Octadecanoyl-sn-glycerol 3-phosphateMetaboCard
PAMDB0015411-Tetradec-7-enoyl-sn-glycerol 3-phosphateMetaboCard
PAMDB0015421-Tetradecanoyl-sn-glycerol 3-phosphateMetaboCard
PAMDB000298Acetyl-CoAMetaboCard
PAMDB000014Adenosine monophosphateMetaboCard
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000140Caprylic acidMetaboCard
PAMDB000381Coenzyme AMetaboCard
PAMDB001612Decanoate (N-C10:0)MetaboCard
PAMDB001617Dodecanoate (N-C12:0)MetaboCard
PAMDB001618Dodecanoly-phosphate (n-C12:0)MetaboCard
PAMDB000049Glycerol 3-phosphateMetaboCard
PAMDB001933Heptadecenoic acidMetaboCard
PAMDB001634Hexadecanoyl-phosphate (n-C16:0)MetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000284Malonyl-CoAMetaboCard
PAMDB001901Margaric acidMetaboCard
PAMDB001822Myristic acidMetaboCard
PAMDB001745Octadecanoate (N-C18:0)MetaboCard
PAMDB001666Octadecanoyl-phosphate (n-C18:0)MetaboCard
PAMDB001667Octadecanoyl-phosphate (n-C18:1)MetaboCard
PAMDB001746Octadecenoate (N-C18:1)MetaboCard
PAMDB000091Palmitic acidMetaboCard
PAMDB001837Palmitoleic acidMetaboCard
PAMDB000383PhosphateMetaboCard
PAMDB000633PyrophosphateMetaboCard
PAMDB001823Stearic acidMetaboCard
PAMDB001757tetradecanoate (n-C14:0)MetaboCard
PAMDB001692Tetradecanoyl-phosphate (n-C14:0)MetaboCard
PAMDB001758Tetradecenoate (N-C14:1)MetaboCard
PAMDB000644UDP-3-O-(3-Hydroxymyristoyl)-N-acetylglucosamineMetaboCard
PAMDB000120Uridine diphosphate-N-acetylglucosamineMetaboCard
PAMDB001838Vaccenic acidMetaboCard
GO Classification:
Function
acyl carrier activity
amino acid binding
binding
carboxylic acid binding
cofactor binding
phosphopantetheine binding
substrate-specific transporter activity
transporter activity
Process
carboxylic acid metabolic process
cellular metabolic process
fatty acid biosynthetic process
fatty acid metabolic process
metabolic process
monocarboxylic acid metabolic process
organic acid metabolic process
oxoacid metabolic process
Gene Properties
Locus tag: PA2966
Strand: -
Entrez Gene ID: 879895
Accession: NP_251656.1
GI: 15598162
Sequence start: 3324947
Sequence End: 3325183
Sequence Length: 236
Gene Sequence: 
>PA2966
ATGAGCACCATCGAAGAACGCGTTAAGAAGATCGTCGCTGAACAACTCGGCGTGAAGGAAGAAGAAGTCACCAACAGCGCTTCCTTCGTCGAAGACCTGGGCGCCGACTCCCTTGACACCGTCGAGCTGGTGATGGCTCTGGAAGAGGAATTCGAGACCGAAATCCCTGACGAGAAAGCTGAAAAGATCACCACCGTTCAGGAAGCCATCGACTACATCGTTGCTCACCAGCAATAA
Protein Properties
Protein Residues: 78
Protein Molecular Weight: 8.7 kDa
Protein Theoretical pI: 3.79
Hydropathicity (GRAVY score): -0.301
Charge at pH 7 (predicted): -14.76
Protein Sequence: 
>PA2966
MSTIEERVKKIVAEQLGVKEEEVTNSASFVEDLGADSLDTVELVMALEEEFETEIPDEKAEKITTVQEAIDYIVAHQQ
References
External Links:
Resource Link
Genome ID: PA2966
Entrez Gene ID: 879895
NCBI Protein ID: 15598162
General Reference: PaperBLAST - Find papers about PA2966 and its homologs