Glutaredoxin-4 (PA3533)

Identification
Name: Glutaredoxin-4
Synonyms:
  • Grx4
  • Monothiol glutaredoxin
Gene Name: grxD
Enzyme Class: Not Available
Biological Properties
General Function: Involved in electron carrier activity
Specific Function: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters (Probable)
Cellular Location: Cytoplasm
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    glutaredoxin+2 Thumb → glutaredoxin+Thumb
    glutaredoxin + 2 Glutathione → glutaredoxin + Glutathione disulfide
    ReactionCard
    Complex Reactions:
    glutaredoxin+Thumb → Thumb+glutaredoxin+Thumb
    glutaredoxin + Uridine 5'-diphosphate → dUDP + glutaredoxin + Water
    ReactionCard
    Thumb+glutaredoxin → Thumb+glutaredoxin+Thumb
    Guanosine diphosphate + glutaredoxin → dGDP + glutaredoxin + Water
    ReactionCard
    Thumb+glutaredoxin → Thumb+glutaredoxin+Thumb
    CDP + glutaredoxin → dCDP + glutaredoxin + Water
    ReactionCard
    Thumb+glutaredoxin → Thumb+glutaredoxin+Thumb
    ADP + glutaredoxin → dADP + glutaredoxin + Water
    ReactionCard
    glutaredoxin+Thumb → glutaredoxin+2 Thumb+Thumb+Thumb
    glutaredoxin + Phosphoadenosine phosphosulfate → glutaredoxin + 2 Hydrogen ion + Adenosine 3',5'-diphosphate + Sulfite
    ReactionCard
    glutaredoxin+2 Thumb → glutaredoxin+Thumb
    glutaredoxin + 2 Glutathione → glutaredoxin + Glutathione disulfide
    ReactionCard
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB000022Adenosine 3',5'-diphosphateMetaboCard
    PAMDB000345ADPMetaboCard
    PAMDB000415CDPMetaboCard
    PAMDB001728dADPMetaboCard
    PAMDB000307dCDPMetaboCard
    PAMDB000209dGDPMetaboCard
    PAMDB000221dUDPMetaboCard
    PAMDB000048GlutathioneMetaboCard
    PAMDB001629Glutathione disulfideMetaboCard
    PAMDB000296Guanosine diphosphateMetaboCard
    PAMDB001633Hydrogen ionMetaboCard
    PAMDB000269Phosphoadenosine phosphosulfateMetaboCard
    PAMDB000100SulfiteMetaboCard
    PAMDB000123Uridine 5'-diphosphateMetaboCard
    PAMDB000142WaterMetaboCard
    GO Classification:
    Function
    catalytic activity
    disulfide oxidoreductase activity
    electron carrier activity
    oxidoreductase activity
    oxidoreductase activity, acting on a sulfur group of donors
    protein disulfide oxidoreductase activity
    Process
    cell redox homeostasis
    cellular homeostasis
    cellular process
    Gene Properties
    Locus tag: PA3533
    Strand: -
    Entrez Gene ID: 880011
    Accession: NP_252223.1
    GI: 15598729
    Sequence start: 3952061
    Sequence End: 3952387
    Sequence Length: 326
    Gene Sequence: 
    >PA3533
ATGGACATCATCGAAACCATTAAAGAGCAGATCGCCAACAACCCCATCCTGCTGTACATGAAGGGTTCGCCGAACGCCCCGCAGTGCGGTTTCTCCTCGCGCGCGGCCCAGGTGCTGATGGCCTGTGGCGAGAAGTTCGCCTACGTCGACATCCTGCAGAACCCGGAAATCCGCGCCAACCTGCCGAAGTACGCGAACTGGCCGACCTTCCCGCAGCTGTGGGTCAATGGCGAACTGGTCGGCGGCAGCGACATCCTCGCCGAGATGTTCGAGAAGGGCGAACTGCAGACCCTGGTCAAGGACGCGGCGGCCAAAGCCAACGCCTGA
    Protein Properties
    Protein Residues: 108
    Protein Molecular Weight: 11.8 kDa
    Protein Theoretical pI: 4.54
    Hydropathicity (GRAVY score): -0.077
    Charge at pH 7 (predicted): -3.08
    Protein Sequence: 
    >PA3533
MDIIETIKEQIANNPILLYMKGSPNAPQCGFSSRAAQVLMACGEKFAYVDILQNPEIRANLPKYANWPTFPQLWVNGELVGGSDILAEMFEKGELQTLVKDAAAKANA
    References
    External Links:
    Resource Link
    Genome ID: PA3533
    Entrez Gene ID: 880011
    NCBI Protein ID: 15598729
    General Reference: PaperBLAST - Find papers about PA3533 and its homologs