Carbamoyl-phosphate synthase small chain (PA4758)

Identification
Name: Carbamoyl-phosphate synthase small chain
Synonyms:
  • Carbamoyl-phosphate synthetase glutamine chain
Gene Name: carA
Enzyme Class:
Biological Properties
General Function: Involved in glutamine catabolic process
Specific Function: 2 ATP + L-glutamine + HCO(3)(-) + H(2)O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
2 Thumb+Thumb+Thumb+Thumb → 2 Thumb+Thumb+Thumb+2 Thumb+Thumb
2 Adenosine triphosphate + L-Glutamine + Water + Hydrogen carbonate → 2 ADP + Carbamoylphosphate + L-Glutamate + 2 Hydrogen ion + Phosphate
ReactionCard
2 Thumb+Thumb+Thumb+Thumb ↔ 2 Thumb+Thumb+Thumb+Thumb
2 Adenosine triphosphate + L-Glutamine + Hydrogen carbonate + Water ↔ 2 ADP + Phosphate + L-Glutamate + Carbamoylphosphate
ReactionCard
2 Thumb+Thumb+Thumb+Thumb+Thumb+Thumb+Thumb ↔ 2 Thumb+Thumb+Thumb+Thumb
2 Adenosine triphosphate + L-Glutamine + Hydrogen carbonate + Water + Ammonia + Carbamic acid + Carboxyphosphate ↔ 2 ADP + Phosphate + L-Glutamate + Carbamoylphosphate
ReactionCard
SMPDB Reactions:
Thumb+Thumb+Thumb+2 Thumb → 2 Adenosine diphosphate+Thumb+L-Glutamic acid+2 Thumb+Thumb+2 Thumb+Thumb
Hydrogen carbonate + Water + L-Glutamine + 2 Adenosine triphosphate → 2 Adenosine diphosphate + Phosphate + L-Glutamic acid + 2 Hydrogen ion + Carbamoylphosphate + 2 ADP + L-Glutamate
ReactionCard
PseudoCyc/BioCyc Reactions:
2 Thumb+Thumb+Thumb+Thumb → 2 Thumb+Thumb+Thumb+2 Thumb+Thumb
2 Adenosine triphosphate + L-Glutamine + Water + Hydrogen carbonate → 2 ADP + Carbamoylphosphate + L-Glutamate + 2 Hydrogen ion + Phosphate
ReactionCard
Complex Reactions:
2 Thumb+Thumb+Thumb+Thumb → 2 Thumb+Thumb+Thumb+Thumb
2 Adenosine triphosphate + L-Glutamine + Carbonic acid + Water → 2 ADP + Inorganic phosphate + L-Glutamate + Carbamoylphosphate
ReactionCard
2 Thumb+Thumb+Thumb+Thumb → 2 Thumb+Thumb+Thumb+Thumb
2 Adenosine triphosphate + L-Glutamine + Carbonic acid + Water → 2 ADP + Inorganic phosphate + L-Glutamate + Carbamoylphosphate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB000253CarbamoylphosphateMetaboCard
PAMDB000510Carbonic acidMetaboCard
PAMDB000153Hydrogen carbonateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001776Inorganic phosphateMetaboCard
PAMDB000055L-GlutamateMetaboCard
PAMDB000163L-GlutamineMetaboCard
PAMDB000383PhosphateMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
carbamoyl-phosphate synthase activity
catalytic activity
ligase activity
ligase activity, forming carbon-nitrogen bonds
Process
biosynthetic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
cellular metabolic process
glutamine family amino acid metabolic process
glutamine metabolic process
metabolic process
nitrogen compound metabolic process
Gene Properties
Locus tag: PA4758
Strand: -
Entrez Gene ID: 881751
Accession: NP_253446.1
GI: 15599952
Sequence start: 5343767
Sequence End: 5344903
Sequence Length: 1136
Gene Sequence: 
>PA4758
TTGACTAAGCCAGCCATACTTGCACTTGCCGACGGCAGCATTTTTCGCGGTGAAGCCATCGGTGCCGACGGCCAGACCGTTGGCGAGGTGGTGTTCAACACCGCCATGACCGGCTACCAGGAAATCCTTACCGATCCTTCCTACGCCCAGCAGATCGTCACCCTGACCTACCCGCACATCGGCAATACCGGTACCACCCCGGAAGACGCCGAGGCCAACCGTGTCTGGGCCGCCGGCCTGATCATTCGCGACCTGCCGCTGATCGCCAGCAACTGGCGCAGCAAGCAGTCGCTGCCTGACTACCTGAAAGCCAACGGCACCGTCGCCATCGCCGGCATCGATACCCGTCGCCTGACTCGCATCCTCCGCGAGAAGGGTTCGCAGAACGGCTGCATCCTGGCTGGTGCCGACGCTACCGAGGAACGCGCGCTGGAGCTGGCTCGCGCCTTCCCCGGCCTGAAGGGCATGGACCTGGCCAAGGAGGTCACCACCGCCGAGCGCTACGAGTGGCGCTCCAGCGTCTGGAACCTGGAAAGCGACAGTCACCCGGAGATCCCGGCCGGTGAACTGCCGTATCACGTGGTGGCCTACGACTACGGCGTCAAGCTGAACATCCTGCGCATGCTGGTGGCGCGCGGCTGCCGCCTGACCGTGGTGCCGGCGCAGACACCGGCCAGCGAAGTGCTGGCGCTGAACCCTGACGGCATCTTCCTTTCCAACGGCCCCGGCGACCCCGAACCGTGCGACTACGCGATCCAGGCGATCCGCGAATTCCTCGATACCGAGATCCCGGTGTTCGGCATCTGCCTCGGCCATCAGTTGCTGGCCCTGGCCTCTGGCGCCAAGACCCTGAAGATGGGCCACGGCCACCACGGCGCCAACCACCCGGTGCAGGACCTGGACAGCGGCGTGGTGATGATCACCAGCCAGAACCACGGTTTCGCGGTCGACGAGAGCACCCTGCCGGACAACCTGCGAGCCACTCACAAGTCGCTGTTCGACGGTACCCTGCAGGGTATCGAGCGCACCGACAAGGTCGCTTTCAGCTTCCAGGGCCACCCCGAGGCGAGCCCCGGTCCGCATGACGTCGCCCCGCTGTTCGACCGCTTCATCTCGGCGATGGCCGAGCGTCGCTGA
Protein Properties
Protein Residues: 378
Protein Molecular Weight: 40.8 kDa
Protein Theoretical pI: 5.23
Hydropathicity (GRAVY score): -0.148
Charge at pH 7 (predicted): -11.23
Protein Sequence: 
>PA4758
MTKPAILALADGSIFRGEAIGADGQTVGEVVFNTAMTGYQEILTDPSYAQQIVTLTYPHIGNTGTTPEDAEANRVWAAGLIIRDLPLIASNWRSKQSLPDYLKANGTVAIAGIDTRRLTRILREKGSQNGCILAGADATEERALELARAFPGLKGMDLAKEVTTAERYEWRSSVWNLESDSHPEIPAGELPYHVVAYDYGVKLNILRMLVARGCRLTVVPAQTPASEVLALNPDGIFLSNGPGDPEPCDYAIQAIREFLDTEIPVFGICLGHQLLALASGAKTLKMGHGHHGANHPVQDLDSGVVMITSQNHGFAVDESTLPDNLRATHKSLFDGTLQGIERTDKVAFSFQGHPEASPGPHDVAPLFDRFISAMAERR
References
External Links:
Resource Link
Genome ID: PA4758
Entrez Gene ID: 881751
NCBI Protein ID: 15599952
General Reference: PaperBLAST - Find papers about PA4758 and its homologs