Glutamine synthetase (PA5119)

Identification
Name: Glutamine synthetase
Synonyms:
  • Glutamate--ammonia ligase
Gene Name: glnA
Enzyme Class:
Biological Properties
General Function: Involved in glutamate-ammonia ligase activity
Specific Function: ATP + L-glutamate + NH(3) = ADP + phosphate + L-glutamine
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
Adenosine triphosphate + L-Glutamate + Ammonia ↔ ADP + Phosphate + L-Glutamine
ReactionCard
SMPDB Reactions:
Thumb+L-Glutamic acid+Thumb+Thumb+Thumb ↔ Thumb+Thumb+Adenosine diphosphate+Thumb
Ammonia + L-Glutamic acid + Adenosine triphosphate + Oxoglutaric acid + L-Glutamate ↔ Phosphate + L-Glutamine + Adenosine diphosphate + ADP
ReactionCard
L-Glutamic acid+Thumb+Thumb+Thumb → Thumb+Thumb+Adenosine diphosphate+Thumb+Thumb
L-Glutamic acid + Adenosine triphosphate + Ammonium + L-Glutamate → L-Glutamine + Hydrogen ion + Adenosine diphosphate + Phosphate + ADP
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
Adenosine triphosphate + L-Glutamate + Ammonia ↔ ADP + Phosphate + L-Glutamine
ReactionCard
Complex Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Thumb
Adenosine triphosphate + L-Glutamate + Ammonium → ADP + L-Glutamine + Hydrogen ion + Phosphate
ReactionCard
Thumb+Thumb+Thumb → Thumb+Thumb+Thumb
Adenosine triphosphate + L-Glutamate + Ammonia → ADP + Inorganic phosphate + L-Glutamine
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB000017AmmoniaMetaboCard
PAMDB001595AmmoniumMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001776Inorganic phosphateMetaboCard
PAMDB000055L-GlutamateMetaboCard
PAMDB000163L-GlutamineMetaboCard
PAMDB000623Oxoglutaric acidMetaboCard
PAMDB000383PhosphateMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
acid-ammonia (or amide) ligase activity
ammonia ligase activity
catalytic activity
glutamate-ammonia ligase activity
ligase activity
ligase activity, forming carbon-nitrogen bonds
Process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
cellular metabolic process
glutamine biosynthetic process
glutamine family amino acid metabolic process
glutamine metabolic process
metabolic process
nitrogen compound metabolic process
nitrogen cycle metabolic process
nitrogen fixation
Gene Properties
Locus tag: PA5119
Strand: +
Entrez Gene ID: 877688
Accession: NP_253806.1
GI: 15600312
Sequence start: 5766484
Sequence End: 5767893
Sequence Length: 1409
Gene Sequence: 
>PA5119
ATGTCGTACAAGTCGCACCAACTGATCAAAGACCATGACGTGAAGTGGGTAGACCTGCGCTTCACCGATACCAAGGGCAAGCAGCAACACGTCACCATGCCGGCTCGCGACGCGCTGGACGATGAGTTCTTCGAAGCCGGCAAGATGTTCGACGGCTCCTCCATCGCCGGCTGGAAAGGCATCGAAGCCTCCGACATGATCCTGATGCCGGACGACAGCACCGCCGTCCTCGATCCGTTCACCGAAGAGCCGACCCTGATCCTGGTCTGCGACATCATCGAGCCGAGCACCATGCAAGGCTACGAGCGCGACCCGCGCAACATCGCCAAGCGCGCCGAGGAGTACCTGAAGTCCACCGGCATCGGCGACACCGTGTTCGTCGGCCCGGAGCCGGAGTTCTTCATCTTCGACGAAGTGAAGTTCAAGTCCGACATCTCCGGCTCGATGTTCAAGATCTTCTCCGAGCAGGCTTCCTGGAACACCGACGCCGACATCGAGTCCGGCAACAAGGGCCATCGCCCGGGCGTGAAGGGCGGCTACTTCCCGGTACCGCCGGTCGACCACGACCATGAAATCCGCACCGCCATGTGCAACGCCCTGGAAGAAATGGGCCTGGTGGTCGAAGTCCACCACCACGAAGTGGCAACCGCCGGCCAGAACGAGATCGGCGTGAAGTTCAACACCCTGGTCGCCAAGGCCGACGAAGTGCAGACCCTGAAGTACTGCGTGCACAACGTCGCCGACGCCTACGGCAAGACCGTGACCTTCATGCCGAAGCCGCTGTACGGCGACAACGGTTCGGGCATGCACGTGCACATGTCGATCTCCAAGGACGGCAAGAACACCTTCGCCGGCGAAGGCTATGCCGGCCTGTCCGAGACCGCCCTGTACTTCATCGGCGGCATCATCAAGCACGGCAAGGCCCTGAACGGCTTCACCAACCCCTCGACCAACTCCTACAAGCGCCTGGTCCCGGGCTTCGAAGCTCCGGTGATGCTGGCCTACTCGGCGCGCAACCGTTCCGCCTCGATCCGTATCCCCTACGTATCCAGCCCGAAGGCCCGCCGTATCGAAGCGCGCTTCCCGGACCCGGCAGCCAACCCCTACCTGGCCTTCGCCGCGCTGCTGATGGCCGGCCTGGACGGCATCCAGAACAAGATCCACCCCGGCGATGCCGCCGACAAGAACCTGTACGACCTGCCGCCGGAAGAGGCGAAGGAAATCCCGCAGGTTTGCGGCAGCCTGAAAGAGGCGCTGGAAGAACTCGACAAGGGCCGCGCGTTCCTGACCAAGGGCGGCGTGTTCACCGACGAGTTCATCGATGCCTACATCGAGCTGAAGAGCGAAGAAGAGATCAAGGTGCGCACCTTCGTGCACCCGCTGGAATACGACCTGTACTACAGCGTCTGA
Protein Properties
Protein Residues: 469
Protein Molecular Weight: 51.9 kDa
Protein Theoretical pI: 4.95
Hydropathicity (GRAVY score): -0.34
Charge at pH 7 (predicted): -18.49
Protein Sequence: 
>PA5119
MSYKSHQLIKDHDVKWVDLRFTDTKGKQQHVTMPARDALDDEFFEAGKMFDGSSIAGWKGIEASDMILMPDDSTAVLDPFTEEPTLILVCDIIEPSTMQGYERDPRNIAKRAEEYLKSTGIGDTVFVGPEPEFFIFDEVKFKSDISGSMFKIFSEQASWNTDADIESGNKGHRPGVKGGYFPVPPVDHDHEIRTAMCNALEEMGLVVEVHHHEVATAGQNEIGVKFNTLVAKADEVQTLKYCVHNVADAYGKTVTFMPKPLYGDNGSGMHVHMSISKDGKNTFAGEGYAGLSETALYFIGGIIKHGKALNGFTNPSTNSYKRLVPGFEAPVMLAYSARNRSASIRIPYVSSPKARRIEARFPDPAANPYLAFAALLMAGLDGIQNKIHPGDAADKNLYDLPPEEAKEIPQVCGSLKEALEELDKGRAFLTKGGVFTDEFIDAYIELKSEEEIKVRTFVHPLEYDLYYSV
References
External Links:
Resource Link
Genome ID: PA5119
Entrez Gene ID: 877688
NCBI Protein ID: 15600312
General Reference: PaperBLAST - Find papers about PA5119 and its homologs