Phosphoenolpyruvic acid (PAMDB000111)

General function:

Involved in phosphoenolpyruvate carboxylase activity

Specific function:

Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle

Gene Name:

ppc

Locus Tag:

PA3687

Molecular weight:

97.8 kDa

Reactions

General function:

Involved in catalytic activity

Specific function:

Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)

Gene Name:

aroF

Locus Tag:

PA1750

Molecular weight:

39.1 kDa

Reactions

General function:

Involved in protein-N(PI)-phosphohistidine-sugar phosphotransferase activity

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine transport

Gene Name:

nagE

Locus Tag:

PA3761

Molecular weight:

60.6 kDa

Reactions

General function:

Involved in magnesium ion binding

Specific function:

Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. It is also a component of the RNA degradosome, a multi-enzyme complex involved in RNA processing and messenger RNA degradation. Its interaction with RNase E is important for the turnover of mRNA, in particular on transcripts encoding enzymes of energy-generating metabolic routes. Its presence in the degradosome is required for the response to excess phosphosugar. May play a regulatory role in the degradation of specific RNAs, such as ptsG mRNA, therefore linking cellular metabolic status with post-translational gene regulation

Gene Name:

eno

Locus Tag:

PA3635

Molecular weight:

45.2 kDa

Reactions

General function:

Involved in catalytic activity

Specific function:

Synthesis of KDO 8-P which is required for lipid A maturation and cellular growth

Gene Name:

kdsA

Locus Tag:

PA3636

Molecular weight:

31.1 kDa

Reactions

General function:

Involved in transferase activity, transferring alkyl or aryl (other than methyl) groups

Specific function:

Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine. Target for the antibiotic phosphomycin

Gene Name:

murA

Locus Tag:

PA4450

Molecular weight:

44.6 kDa

Reactions

General function:

Involved in magnesium ion binding

Specific function:

ATP + pyruvate = ADP + phosphoenolpyruvate

Gene Name:

pykF

Locus Tag:

PA1498

Molecular weight:

51.5 kDa

Reactions

General function:

Involved in sugar:hydrogen symporter activity

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport

Gene Name:

fruA

Locus Tag:

PA3560

Molecular weight:

59 kDa

Reactions

General function:

Involved in magnesium ion binding

Specific function:

ATP + pyruvate = ADP + phosphoenolpyruvate

Gene Name:

pykA

Locus Tag:

PA4329

Molecular weight:

52.3 kDa

Reactions

General function:

Involved in phosphoenolpyruvate carboxykinase (ATP) activity

Specific function:

ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO(2)

Gene Name:

pckA

Locus Tag:

PA5192

Molecular weight:

55.7 kDa

Reactions

General function:

Involved in catalytic activity

Specific function:

Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate

Gene Name:

ppsA

Locus Tag:

PA1770

Molecular weight:

85.8 kDa

Reactions

General function:

Involved in protein binding

Specific function:

Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. Enzyme I- Ntr transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (NPr). Could function in the transcriptional regulation of sigma-54 dependent operons in conjunction with the NPr (ptsO) and EIIA-Ntr (ptsN) proteins

Gene Name:

ptsP

Locus Tag:

PA0337

Molecular weight:

83.6 kDa

Reactions

General function:

Involved in sugar:hydrogen symporter activity

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in galactitol transport

Gene Name:

gatB

Locus Tag:

PA4484

Molecular weight:

53.1 kDa

Reactions

General function:

Involved in transporter activity

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in galactitol transport

Gene Name:

gatA

Locus Tag:

PA4483

Molecular weight:

51.9 kDa

Reactions

General function:

Involved in phosphoenolpyruvate-dependent sugar phosphotransferase system

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in galactitol transport

Gene Name:

gatC

Locus Tag:

PA4482

Molecular weight:

10.5 kDa