Identification
Name: Phosphoenolpyruvate carboxylase
Synonyms:
  • PEPC
  • PEPCase
Gene Name: ppc
Enzyme Class:
Biological Properties
General Function: Involved in phosphoenolpyruvate carboxylase activity
Specific Function: Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+ThumbThumb+Thumb+Thumb+Thumb
Thumb+ThumbThumb+Thumb+Thumb
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+ThumbThumb+Thumb+Thumb+Thumb
Thumb+ThumbThumb+Thumb+Thumb
Thumb+ThumbThumb+Thumb+Thumb
Thumb
oxaloacetate + phosphate ↔ phosphoenolpyruvate + hydrogen carbonate
ReactionCard
Complex Reactions:
Thumb+ThumbThumb+Thumb+Thumb
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000568Carbon dioxideMetaboCard
PAMDB000510Carbonic acidMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001776Inorganic phosphateMetaboCard
PAMDB000092Oxalacetic acidMetaboCard
PAMDB000383PhosphateMetaboCard
PAMDB000111Phosphoenolpyruvic acidMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
carbon-carbon lyase activity
carboxy-lyase activity
catalytic activity
lyase activity
phosphoenolpyruvate carboxykinase activity
phosphoenolpyruvate carboxylase activity
Process
acetyl-CoA catabolic process
acetyl-CoA metabolic process
carbon fixation
cellular metabolic process
coenzyme metabolic process
cofactor metabolic process
metabolic process
organic substance metabolic process
tricarboxylic acid cycle
Gene Properties
Locus tag: PA3687
Strand: -
Entrez Gene ID: 879083
Accession: NP_252377.1
GI: 15598883
Sequence start: 4127756
Sequence End: 4130392
Sequence Length: 2636
Gene Sequence:
>PA3687
ATGCCGGAAATCGATGCGCGCCTGCGCGAGGACGTCCACCAACTGGGCGAATTGCTCGGCGACACCATCCGCGAGCAGTACGGCCCGCGGTTCCTCGACAAGATCGAGCTGATCCGCAAGGGCGCCAAGGCTGCCCGCCGCGGTTCCGCGGAGGGCGCCCAGCAGCTCACCGCCACCCTCGACGGGCTCGAGGAAGACGAACTGCTGCCGGTGGCGCGGGCCTTCAACCAGTTCCTCAACCTGGCCAATATCGCCGAGCAATACCACCGTATCCGCCGGCGCCGGCCGAACGAGCCGGAACCCTTCGAGAACCTGGTGCTGGAAGAGCTGCTGGGGCGTCTCAAGGACGCCGGGCATGCCCCCGGGCAACTGGCTCGCCAGCTCGCCGGGCTGGAGATCGAACTGGTGCTGACCGCCCATCCCACCGAGGTGGCGCGGCGCACGCTGATCCAGAAATACGATGCGATCACCGCGCAACTGGCGGCCAAGGACCATGCCGACCTGCTGCCGGAGGAGCGCAGTCGCATCCAGCAGCGCCTGCAGCGGCTGGTGGCCGAGGCCTGGCATACCGACGAGATCCGCAAGGTCCGGCCGACCCCGGTGGACGAGGCGAAATGGGGCTTCGCGGTGATCGAACATTCTCTCTGGCAGGCCTTGCCGAACGTCCTTCGGCACGTCGACGAGGTACTCCTGCGCAGCACCGGCGAACGCCTGCCGTTGACCGCCGCGCCGCTGCGCTTCGCGTCCTGGATGGGGGGCGACCGCGACGGCAATCCCAACGTCACCGCCAGCGTGACCCGCGAGGTCCTGCTGCTGGCGCGCTGGATGGCCGCCGACCTGTACCTGCGCGATATCGACCGACTGGCCGCCGAGCTGTCCATGCAGCAGGCCTCGCCGCAGCTGCTGGCGCGGGTCGGCGATAGCGCCGAGCCCTATCGCGCCCTGCTCAAGCAATTGCGCGAGCGCCTGCGCGTGACCCGCAACTGGACCCACCAGGCCCTGGCCGGCGAGGTGCCGGCCGCGGAGGGCGTCCTGGAGCACAACCGCGACCTGGTCGAGCCGCTGCAACTGTGCCACGAGTCGCTGCACGCCTGCGGCATGGGCGTGATCGCCGATGGCGCGTTGCTCGACTGCCTGCGCCGCGCCGCCACCTTCGGCCTGTTCCTGGTACGCCTGGACGTGCGCCAGGACTCGGCCCGCCATGCCGCCGCGCTGAGCGAGATCACCGAGTACCTGGAGCTGGGCAGCTACGACGAGTGGGACGAGAAGACCCGCCTGGAATTCCTTCTCGAGGAACTGAACAGCCGCCGCCCCCTGCTGCCGGCGCACTACCAGCCTTCGGCGGATACCGCCGAGGTGCTCGCCACCTGCCGGGCGATCGCCGCCGCACCACCGGCGTCGCTGGGGTCCTACGTGATCTCGATGGCCGGCCAGCCGTCCGACGTGCTGGCGGTGCAACTGCTGCTAAAGGAAAGCGGCGTCGACTGGCCGATGCGCGTGGTGCCGCTGTTCGAGACCCTCGACGACCTGGACAACGCCGGCCCCTGCATGGAGCGCCTGCTGACGCTGCCGGGCTACCGTTCGCGGCTGTCCGGGGTGCAGGAAGTGATGATCGGCTACTCCGATTCGGCCAAGGACGCCGGTACCCTCACGGCGGCCTGGGCGCAGTACCGGGCGCAGGAGAAACTGGTGGAGATCTGCCGCCAGCACGAGGTCGAGTTGCTGCTCTTCCACGGCCGCGGCGGTACCGTCGGTCGCGGCGGCGGGCCGGCCCACGCGGCGATCCTGTCGCAGCCGCCGGGTTCGGTGGCCGGGCGCTTCCGGGTCACCGAACAGGGCGAGATGATCCGCTTCAAGTTCGGTCTGCCGGACATCGCCGAACAGAACCTCAATCTCTACCTCGCCGCAGTGCTGGAAGCGACCCTGATGCCGCCGCCGGCTCCGGAGCCGGCCTGGCGCGCGCAGATGGACCGCCTGGCGAAGGACGCGCTGCTGGCCTACCGCAGGGTGGTGCGCGACGATCCGCAGTTCGTCGAGTATTTCCGCCTGGCCACGCCCGAGCAGGAACTGGGCCGTCTGCCGCTGGGCAGCCGCCCGGCCAAGCGCCGCGAAGGCGGGGTGGAGAGCCTGCGGGCGATTCCCTGGATCTTCGCCTGGACCCAGACGCGCCTGATGCTGCCGGCATGGCTTGGCTGGGAGACCGCCTTGCTGAACGCCATCGAGCGTGGCGAGGGCGCGCTGCTCGGGCAGATGCGCGAGCAATGGCCGTTCTTCACCACCCGCATCGACATGCTGGAAATGGTCCTGGCCAAGGCCGACGCGGATATCGCGCGGCTCTACGACGAACGTCTAGTGCCGCTCGAGCTGCGTCCGCTGGGGCGTCGTTTACGCGACCTATTGTCGCAGGCGGTGCGCGTGGTGCTGGGACTGACCGGGCAGTCGCTGCTGCTCGCCCACGCCAGCGAGACCCGCGAGTCGATCAGCGTGCGCAACAGCTATCTAGACCCGCTGCACCTGCTCCAGGCTGAGCTTCTGGCCCGTTCGCGGCGCTGCCGGGGCGACGCCTGCGGCGGCCTGGAGCAGGCGCTGCTGGTGACGGTCGCGGGGGTCGCCGCCGGACTGCGCAACACCGGATGA
Protein Properties
Protein Residues: 878
Protein Molecular Weight: 97.8 kDa
Protein Theoretical pI: 6.15
Hydropathicity (GRAVY score): -0.205
Charge at pH 7 (predicted): -9.59
Protein Sequence:
>PA3687
MPEIDARLREDVHQLGELLGDTIREQYGPRFLDKIELIRKGAKAARRGSAEGAQQLTATLDGLEEDELLPVARAFNQFLNLANIAEQYHRIRRRRPNEPEPFENLVLEELLGRLKDAGHAPGQLARQLAGLEIELVLTAHPTEVARRTLIQKYDAITAQLAAKDHADLLPEERSRIQQRLQRLVAEAWHTDEIRKVRPTPVDEAKWGFAVIEHSLWQALPNVLRHVDEVLLRSTGERLPLTAAPLRFASWMGGDRDGNPNVTASVTREVLLLARWMAADLYLRDIDRLAAELSMQQASPQLLARVGDSAEPYRALLKQLRERLRVTRNWTHQALAGEVPAAEGVLEHNRDLVEPLQLCHESLHACGMGVIADGALLDCLRRAATFGLFLVRLDVRQDSARHAAALSEITEYLELGSYDEWDEKTRLEFLLEELNSRRPLLPAHYQPSADTAEVLATCRAIAAAPPASLGSYVISMAGQPSDVLAVQLLLKESGVDWPMRVVPLFETLDDLDNAGPCMERLLTLPGYRSRLSGVQEVMIGYSDSAKDAGTLTAAWAQYRAQEKLVEICRQHEVELLLFHGRGGTVGRGGGPAHAAILSQPPGSVAGRFRVTEQGEMIRFKFGLPDIAEQNLNLYLAAVLEATLMPPPAPEPAWRAQMDRLAKDALLAYRRVVRDDPQFVEYFRLATPEQELGRLPLGSRPAKRREGGVESLRAIPWIFAWTQTRLMLPAWLGWETALLNAIERGEGALLGQMREQWPFFTTRIDMLEMVLAKADADIARLYDERLVPLELRPLGRRLRDLLSQAVRVVLGLTGQSLLLAHASETRESISVRNSYLDPLHLLQAELLARSRRCRGDACGGLEQALLVTVAGVAAGLRNTG
References
External Links:
Resource Link
Genome ID: PA3687
Entrez Gene ID: 879083
NCBI Protein ID: 15598883
General Reference: PaperBLAST - Find papers about PA3687 and its homologs