Identification
Name: Phosphoenolpyruvate-protein phosphotransferase ptsP
Synonyms:
  • Enzyme I-Ntr
  • Phosphotransferase system, enzyme I
Gene Name: ptsP
Enzyme Class:
Biological Properties
General Function: Involved in protein binding
Specific Function: Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. Enzyme I- Ntr transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (NPr). Could function in the transcriptional regulation of sigma-54 dependent operons in conjunction with the NPr (ptsO) and EIIA-Ntr (ptsN) proteins
Cellular Location: Cytoplasm (Probable)
KEGG Pathways:
KEGG Reactions:
Thumb+Protein histidineThumb+Protein N(pi)-phospho-L-histidine
Phosphoenolpyruvic acid + Protein histidine ↔ Pyruvic acid + Protein N(pi)-phospho-L-histidine
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+protein L-histidineThumb+protein N(pi)-phospho-L-histidine
Phosphoenolpyruvic acid + protein L-histidine → Pyruvic acid + protein N(pi)-phospho-L-histidine
ReactionCard
Thumb+Protein histidineThumb+Protein N(pi)-phospho-L-histidine
Phosphoenolpyruvic acid + Protein histidine ↔ Pyruvic acid + Protein N(pi)-phospho-L-histidine
ReactionCard
PAMDB110154+PTS-I-HistidinesPAMDB110761+PTS-I-pi-phospho-L-histidines
phosphoenolpyruvate + PTS-I-Histidines → pyruvate + PTS-I-pi-phospho-L-histidines
ReactionCard
Complex Reactions:
Thumb+protein L-histidineThumb+protein N(pi)-phospho-L-histidine
Phosphoenolpyruvic acid + protein L-histidine → Pyruvic acid + protein N(pi)-phospho-L-histidine
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000111Phosphoenolpyruvic acidMetaboCard
PAMDB000102Pyruvic acidMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
catalytic activity
cation transmembrane transporter activity
cation:sugar symporter activity
ion transmembrane transporter activity
phosphoenolpyruvate-protein phosphotransferase activity
phosphotransferase activity, nitrogenous group as acceptor
solute:cation symporter activity
substrate-specific transmembrane transporter activity
sugar:hydrogen symporter activity
transferase activity
transferase activity, transferring phosphorus-containing groups
transmembrane transporter activity
transporter activity
Process
carbohydrate transport
cellular metabolic process
establishment of localization
metabolic process
phosphate metabolic process
phosphoenolpyruvate-dependent sugar phosphotransferase system
phosphorus metabolic process
phosphorylation
transport
Gene Properties
Locus tag: PA0337
Strand: +
Entrez Gene ID: 882232
Accession: NP_249028.1
GI: 15595534
Sequence start: 378598
Sequence End: 380877
Sequence Length: 2279
Gene Sequence:
>PA0337
ATGCTCAACACGCTGCGCAAGATCGTCCAGGAAGTGAACTCCGCCAAGGATCTGAAGGCGGCGCTGGGCATCATCGTGCAGCGGGTCAAGGAAGCCATGGGTACCCAGGTCTGCTCGGTGTACCTGCTCGACACCGAGACCCAGCGTTTCGTCCTGATGGCCACCGAAGGCCTCAACAAGCGTTCCATCGGCAAGGTCAGCATGGCTCCCAGCGAAGGCCTGGTCGGCCTGGTCGGCACCCGCGAGGAGCCGCTCAACCTGGAGAACGCCGCCGCCCACCCGCGCTACCGCTATTTCGCCGAGACCGGCGAGGAGCGCTACGCGTCGTTCCTCGGCGCGCCGATCATCCACCATCGGCGGGTGATGGGGGTGCTGGTGGTGCAGCAGAAGGAGCGCCGCCAGTTCGACGAAGGCGAGGAAGCCTTCCTCGTCACCATGAGCGCCCAGCTCGCCGGGGTCATCGCGCATGCCGAGGCGACCGGTTCGATCCGCGGCCTGGGCAAGCTCGGCAAGGGCATCCAGGAAGCCAAGTTCGTCGGCGTGCCCGGCGCCCCCGGGGTCGGGGTGGGCAAGGCGGTGGTGGTGTTGCCGCCGGCCGACCTGGAAGTGGTGCCGGACAAGCAGGTCGACGACATCGACGCCGAGATCGCCCTGTTCAAGCAGGCCCTGGAGGGCGTTCGCGCCGACATGCGCGCGCTGTCGAGCAAGCTCGCCAGCCAGCTGCGCAAGGAAGAACGCGCGCTGTTCGACGTCTACCTGATGATGCTCGACGATGCCTCCATCGGCAACGAGGTCAAGCGCATCATCCGTACCGGCCAGTGGGCCCAGGGCGCCCTGCGCCAGGTGGTGATGGAGCACGTGCAGCGCTTCGAGCTGATGGACGACGCCTATCTCCGCGAGCGCGCCTCCGACGTCAAGGACATAGGTCGCCGCCTGCTCGCCTACCTCCAGGAAGAGCGCAAGCAGAACCTGACCTACCCGGAACAGACCATCATCGTCAGCGAGGAGCTGTCGCCGGCGATGCTCGGCGAGGTGCCGGAAGGGCGCCTGGTCGGCCTGGTCTCGGTGCTCGGCTCGGGCAACTCGCACGTGGCGATCCTCGCCCGTGCCATGGGCATCCCCACGGTGATGGGGGCGGTCGACCTGCCGTACTCCAAGGTCGACGGCATCGACCTGATCGTCGATGGCTACCACGGCGAGGTCTACACCAACCCCTCCGCCGAGCTGGTGCGCCAGTACAGCGACGTGGTCGCCGAGGAGCGCGAGCTGAGCAAGGGCCTGGCGGCCCTGCGCGAGCTGCCCTGCGAGACCCTCGACGGCCACCGCATGCCGCTCTGGGTCAACACCGGCCTGCTCGCCGATGTCGCCCGCGCCCAGGAGCGTGGCGCCGAGGGCGTGGGCCTGTACCGCACCGAAGTGCCGTTCATGATCAACGACCGCTTCCCCAGCGAGAAGGAACAGTTGGCGATCTACCGCGAGCAGCTCAGTGCCTTCCACCCGCTGCCGGTGACCATGCGCACCCTGGATATCGGCGGCGACAAGGCGCTGTCCTACTTCCCGATCAAGGAAGACAACCCGTTCCTCGGCTGGCGCGGCATCCGCGTCACCCTCGACCACCCGGAGATCTTCCTGGTCCAGACCCGCGCCATGCTCAAGGCCAGCGAAGGACTGGACAACCTGCGCATCCTGCTGCCGATGATCTCCGGCACCCACGAGCTGGAAGAGGCCCTGCACCTGATCCACCGCGCCTGGGGCGAGGTGCGCGACGAGGGCGTGGACATCGCCATGCCGCCCATCGGCATGATGGTCGAGATTCCCGCCGCCGTGTACCAGACCCGCGAGCTGGCCCGCCAGGTCGACTTCCTTTCGGTCGGTTCGAACGACCTGACCCAGTACCTGCTGGCGGTCGACCGCAACAATCCGCGGGTCGCCGACCTCTACGACTACCTGCATCCGGCCGTTCTGCATGCGTTGAAGAAGGTGGTCGACGATGCCCACCTGGAAGGCAAGCCGGTGAGCATCTGCGGCGAGATGGCCGGCGATCCCGCGGCTGCCGTGCTGCTGATGGCGATGGGCTTCGACAGCCTGTCGATGAACGCCACCAACCTGCCCAAGGTGAAGTGGCTGCTGCGCCAGATCACCCTGGACAAGGCCCGGGACCTGCTCGGCCAGTTGCTCACCTTCGACAACCCGCAGGTCATCCACAGCTCGCTGCACCTGGCGTTGCGCAACCTCGGCCTGGGTCGCGTGATCAACCCGGCGGCTACCGTCCAGCCCTGA
Protein Properties
Protein Residues: 759
Protein Molecular Weight: 83.6 kDa
Protein Theoretical pI: 5.56
Hydropathicity (GRAVY score): -0.047
Charge at pH 7 (predicted): -14.7
Protein Sequence:
>PA0337
MLNTLRKIVQEVNSAKDLKAALGIIVQRVKEAMGTQVCSVYLLDTETQRFVLMATEGLNKRSIGKVSMAPSEGLVGLVGTREEPLNLENAAAHPRYRYFAETGEERYASFLGAPIIHHRRVMGVLVVQQKERRQFDEGEEAFLVTMSAQLAGVIAHAEATGSIRGLGKLGKGIQEAKFVGVPGAPGVGVGKAVVVLPPADLEVVPDKQVDDIDAEIALFKQALEGVRADMRALSSKLASQLRKEERALFDVYLMMLDDASIGNEVKRIIRTGQWAQGALRQVVMEHVQRFELMDDAYLRERASDVKDIGRRLLAYLQEERKQNLTYPEQTIIVSEELSPAMLGEVPEGRLVGLVSVLGSGNSHVAILARAMGIPTVMGAVDLPYSKVDGIDLIVDGYHGEVYTNPSAELVRQYSDVVAEERELSKGLAALRELPCETLDGHRMPLWVNTGLLADVARAQERGAEGVGLYRTEVPFMINDRFPSEKEQLAIYREQLSAFHPLPVTMRTLDIGGDKALSYFPIKEDNPFLGWRGIRVTLDHPEIFLVQTRAMLKASEGLDNLRILLPMISGTHELEEALHLIHRAWGEVRDEGVDIAMPPIGMMVEIPAAVYQTRELARQVDFLSVGSNDLTQYLLAVDRNNPRVADLYDYLHPAVLHALKKVVDDAHLEGKPVSICGEMAGDPAAAVLLMAMGFDSLSMNATNLPKVKWLLRQITLDKARDLLGQLLTFDNPQVIHSSLHLALRNLGLGRVINPAATVQP
References
External Links:
Resource Link
Genome ID: PA0337
Entrez Gene ID: 882232
NCBI Protein ID: 15595534
General Reference: PaperBLAST - Find papers about PA0337 and its homologs