| Identification |
| Name: |
Galactitol-specific phosphotransferase enzyme IIA component |
| Synonyms: |
- EIIA-Gat
- PTS system galactitol-specific EIIA component
|
| Gene Name: |
gatA |
| Enzyme Class: |
|
| Biological Properties |
| General Function: |
Involved in transporter activity |
| Specific Function: |
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in galactitol transport |
| Cellular Location: |
Cytoplasm (Potential) |
| KEGG Pathways: |
- Amino sugar and nucleotide sugar metabolism pae00520
- Ascorbate and aldarate metabolism pae00053
- Fructose and mannose metabolism pae00051
- Galactose metabolism pae00052
- Glycolysis / Gluconeogenesis pae00010
- Metabolic pathways pae01100
- Microbial metabolism in diverse environments pae01120
- Pentose phosphate pathway pae00030
- Starch and sucrose metabolism pae00500
|
| KEGG Reactions: |
|
 | + | Protein N(pi)-phospho-L-histidine | ↔ |  | + | Protein histidine |
| | |
Protein N(pi)-phospho-L-histidine | + | Sugar | ↔ | Protein histidine | + |  |
| |
|
| SMPDB Reactions: |
|
| + | HPr - phosphorylated | → | Galactose 1-phosphate | + | HPr | + |  |
| |
|
| PseudoCyc/BioCyc Reactions: |
|
| Complex Reactions: |
|
Protein EIIA N(pi)-phospho-L-histidine | + | protein EIIB | → | protein EIIA | + | protein EIIB N(pi)-phospho-L-histidine/cysteine |
| Protein EIIA N(pi)-phospho-L-histidine + protein EIIB → protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine ReactionCard |
|
| Transports: |
Not Available |
| Metabolites: |
|
| GO Classification: |
| Function |
|---|
| cation transmembrane transporter activity | | cation:sugar symporter activity | | ion transmembrane transporter activity | | solute:cation symporter activity | | substrate-specific transmembrane transporter activity | | sugar:hydrogen symporter activity | | transmembrane transporter activity | | transporter activity | | Process |
|---|
| carbohydrate transport | | establishment of localization | | phosphoenolpyruvate-dependent sugar phosphotransferase system | | transport |
|
| Gene Properties |
| Locus tag: |
PA4483 |
| Strand: |
+ |
| Entrez Gene ID: |
881180 |
| Accession: |
NP_253173.1 |
| GI: |
15599679 |
| Sequence start: |
5013974 |
| Sequence End: |
5015428 |
| Sequence Length: |
1454 |
| Gene Sequence: |
>PA4483
ATGCTGCATCAATTGACCCTCGCCGAGATCGCCCGCGCCCTCGCCGACAAGCAATTTTCCGCCGAAGAGCTGACCCGCACCCTGCTCGGTCGCATCCGGCAGCTGGATCCCCAGCTCAACAGTTTCATCAGCATCACCGACGACCTGGCCATCGCCCAGGCCAAGGCAGCCGACGAACGGCGCGCCAACGGCGAGAACGGCGCCCTGCTCGGCGCGCCGATCGCCCACAAGGACCTGTTCTGCACCCAGGGCGTACGCACCAGCTGCGGTTCGAAGATGCTCGACAACTTCGTCTCGCCCTACGACGCCACCGTGGTCGAGAAGCTCACCGCCGCCGGCGCCGTTACCCTCGGCAAGCTGAACATGGATGAATTCGCCATGGGCTCGTCGAACCAGTCCAGCCACTACGGCGCGGTGAAGAACCCCTGGAGCCTCGACCGCGTGCCGGGCGGCTCCTCCGGCGGTTCCGCCGCGGCAGTCGCCGCGCGCCTGCTGCCGGCCGCCACCGGCACCGATACCGGCGGCTCGATCCGCCAACCGGCGGCGCTGACCAACCTCACCGGGATCAAGCCAACCTACGGCCGGGTTTCCCGCTGGGGCATGATCGCCTACGCTTCCAGCCTCGACCAGGGCGGCCCGCTGGCGCGCACCGCCGAGGACTGCGCGCTGATGCTGGGGGTGATGGCCGGATTCGATCCGAAGGACTCGACCAGCGTCGAACAGCCGGTGGACGACTACCTGGCCGCCCTGCAGAAGCCGCTGAGCGGCCTGCGCATCGGCCTGCCGCGGGAATACTTCGGCGCCGGCCTCGACAGCCGCATCGCCGACGCGGTGCTGGCCGTGGTCGAGGAGCTGAAGACGCTCGGCGCCACGGTGAAGGACATTTCCCTGCCGAACATGCAGCACGCCATCCCGGCCTACTACGTAATCGCGCCGGCCGAGGCGTCCTCCAACCTGTCGCGCTTCGACGGCGTGCGCTATGGCTATCGTTGCGACGCCCCGCAGAACCTGGAAGACCTGTACAAGCGCTCGCGCGCGGAAGGCTTCGGCAGCGAAGTGAAGAACCGCATCATGGTCGGCACCTACGCACTCTCGGCCGGCTACTACGATGCCTATTACCTGCAGGCTCAGAAGATTCGCCGGCTGATCAAGAACGACTTCGTCAGCGCCTTTGCCGAAGTGGACGTGATCCTCGGCCCGACCACGCCGAACCCGGCCTGGAAGATCGGCGAGAAGAACGACGACCCGGTTTCCCAGTACCTGGAAGACATCTACACCATCACCGCCAACCTCGCCGGCCTGCCGGGGCTGTCCATGCCCGCCGGCTTCGTCGACGGCCTGCCGGTGGGTGTCCAGTTGCTCGCGCCCTACTTCCAGGAAGGCCGCCTGCTCAACGTCGCGCACCAGTACCAGCAGGTCAGCGACTGGCACACCCGCACCCCGGCCGGCTTCTAA |
| Protein Properties |
| Protein Residues: |
484 |
| Protein Molecular Weight: |
51.9 kDa |
| Protein Theoretical pI: |
5.5 |
| Hydropathicity (GRAVY score): |
-0.119 |
| Charge at pH 7 (predicted): |
-5.67 |
| Protein Sequence: |
>PA4483
MLHQLTLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGENGALLGAPIAHKDLFCTQGVRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVKNPWSLDRVPGGSSGGSAAAVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSVEQPVDDYLAALQKPLSGLRIGLPREYFGAGLDSRIADAVLAVVEELKTLGATVKDISLPNMQHAIPAYYVIAPAEASSNLSRFDGVRYGYRCDAPQNLEDLYKRSRAEGFGSEVKNRIMVGTYALSAGYYDAYYLQAQKIRRLIKNDFVSAFAEVDVILGPTTPNPAWKIGEKNDDPVSQYLEDIYTITANLAGLPGLSMPAGFVDGLPVGVQLLAPYFQEGRLLNVAHQYQQVSDWHTRTPAGF |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA4483 and its homologs
|
