Identification
Name: Pyruvate kinase I
Synonyms:
  • PK-1
Gene Name: pykF
Enzyme Class:
Biological Properties
General Function: Involved in magnesium ion binding
Specific Function: ATP + pyruvate = ADP + phosphoenolpyruvate
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
Thumb+ThumbdGDP+Thumb
Nucleoside triphosphate+ThumbNDP+Thumb
Nucleoside triphosphate + Pyruvic acid ↔ NDP + Phosphoenolpyruvic acid
ReactionCard
SMPDB Reactions:
Thumb+Adenosine diphosphate+Thumb+ThumbThumb+Thumb
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+ThumbThumb+Thumb
Complex Reactions:
Thumb+ThumbThumb+Thumb
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB001728dADPMetaboCard
PAMDB000412dATPMetaboCard
PAMDB000209dGDPMetaboCard
PAMDB000389dGTPMetaboCard
PAMDB000296Guanosine diphosphateMetaboCard
PAMDB000319Guanosine triphosphateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000111Phosphoenolpyruvic acidMetaboCard
PAMDB000102Pyruvic acidMetaboCard
GO Classification:
Function
alkali metal ion binding
binding
catalytic activity
cation binding
ion binding
kinase activity
magnesium ion binding
metal ion binding
potassium ion binding
pyruvate kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
alcohol metabolic process
glucose catabolic process
glucose metabolic process
glycolysis
hexose metabolic process
metabolic process
monosaccharide metabolic process
small molecule metabolic process
Gene Properties
Locus tag: PA1498
Strand: -
Entrez Gene ID: 881682
Accession: NP_250189.1
GI: 15596695
Sequence start: 1626062
Sequence End: 1627495
Sequence Length: 1433
Gene Sequence:
>PA1498
ATGACAGCCGACAAGAAAGCCAAGATCCTCGCCACCCTCGGCCCGGCCACCCGCAGCCGCGACGATATCCGTGCCCTGGTGGAGGCCGGCGCCAACCTGCTCCGCCTGAACTTCAGCCACGGCGACTATGCCGATCACGCGCAGCGCTTCGCCTGGGTGCGCGAGGTGGAAGCGGAGCTGAACTACCCGATCGGCGTGCTCATGGACCTGCAGGGTCCGAAGCTGCGGGTCGGCCGCTTCGCCGCCGGTGCCGTGCAATTGCAGCGTGGGCAGACCTTCACCCTCGACCTCAGCGACGCCCCCGGCGACGAGCGGCGGGTCAACCTGCCGCATCCGGAGATCATCCATGCCCTGGAACCGGGCATGAGCCTGCTGCTGGACGACGGCAAGATCCGCCTGGAAGTGGTCAACTGCCACAGCGACGCCATCGAGACCCGCGTGGCGGTGGGTGGCGAGCTGTCCGATCGCAAGGGCGTCAACGTGCCGGAAGCGGTGCTGCAACTCAGCCCGCTGACCGACAAGGACCGCCGCGATCTGGCCTTCGGCCTGGAACTGGGGGTCGACTGGGTGGCGCTGTCCTTCGTGCAACGCCCGGAGGACATCGACGAGGCCCGTGGGCTGATCGGCGACAAGGCCTTCCTCATGGCCAAGATCGAGAAGCCCAGCGCGGTGAGCGCCATCGAGGCGATCGCCGAGCGCGCCGACGCGATCATGGTGGCGCGCGGCGACCTCGGCGTAGAGGTGCCGGCGGAGAGCGTGCCAGGCATCCAGAAACGCATCGTCCAGGTCTGCCGCCAGCTCGGCAAGCCGGTGGTGGTGGCCACCCAGATGCTCGAGTCGATGCGCTTCTCCCCCGCCCCGACCCGCGCCGAGGTGACCGACGTAGCCACCGCGGTGGGCGCCGGCGCCGACGCGGTGATGCTCTCGGCGGAAACCGCTTCCGGACAATACCCTCGCGAGGCGGTAGAGATGATGGCGAAGATCGTCCGCCAGGTGGAGGCCGAGCCGGACTACCACGTCCAGCTCGAGGTCAACCGTCCGCAGCCCGACGCTACCGTCTCCGATGCGATCAGCTGCGCGATCCGCCGGGTCAGCCGGATCCTCCCGGTGGCGGTGCTGGTGAACTACACCGAGTCGGGCAACTCGACCCTGCGCGCCGCCCGCGAGCGGCCCAAGGCGCCGATCCTCAGCCTGACCCCGAACCTGCGTACCGCGCGGCGACTGACCGTGGCCTGGGGCGTGTATTCGGTGGTCAACGAGCAACTGGCGCACGTCGACGAGATCTGCTCGACCGCCCTCGACATCGCCCTGGCCCAGCGCATGGCGCGCCGCGGCGACACCGTGGTGGTCACCGCCGGCGTACCGTTCGGTCGCCCCGGCTCGACCAACATGCTGCGCATCGAGACCGTGGCGCCGCCGCTGGGAGATCTCTGA
Protein Properties
Protein Residues: 477
Protein Molecular Weight: 51.5 kDa
Protein Theoretical pI: 5.56
Hydropathicity (GRAVY score): -0.048
Charge at pH 7 (predicted): -6.41
Protein Sequence:
>PA1498
MTADKKAKILATLGPATRSRDDIRALVEAGANLLRLNFSHGDYADHAQRFAWVREVEAELNYPIGVLMDLQGPKLRVGRFAAGAVQLQRGQTFTLDLSDAPGDERRVNLPHPEIIHALEPGMSLLLDDGKIRLEVVNCHSDAIETRVAVGGELSDRKGVNVPEAVLQLSPLTDKDRRDLAFGLELGVDWVALSFVQRPEDIDEARGLIGDKAFLMAKIEKPSAVSAIEAIAERADAIMVARGDLGVEVPAESVPGIQKRIVQVCRQLGKPVVVATQMLESMRFSPAPTRAEVTDVATAVGAGADAVMLSAETASGQYPREAVEMMAKIVRQVEAEPDYHVQLEVNRPQPDATVSDAISCAIRRVSRILPVAVLVNYTESGNSTLRAARERPKAPILSLTPNLRTARRLTVAWGVYSVVNEQLAHVDEICSTALDIALAQRMARRGDTVVVTAGVPFGRPGSTNMLRIETVAPPLGDL
References
External Links:
Resource Link
Genome ID: PA1498
Entrez Gene ID: 881682
NCBI Protein ID: 15596695
General Reference: PaperBLAST - Find papers about PA1498 and its homologs