dATP (PAMDB000412)

General function:

Involved in nucleic acid binding

Specific function:

In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity. It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template

Gene Name:

polA

Locus Tag:

PA5493

Molecular weight:

99.8 kDa

Reactions

General function:

Involved in DNA binding

Specific function:

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease

Gene Name:

dnaQ

Locus Tag:

PA1816

Molecular weight:

26.8 kDa

Reactions

General function:

Involved in nucleotide binding

Specific function:

The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA

Gene Name:

dnaX

Locus Tag:

PA1532

Molecular weight:

73.3 kDa

Reactions

General function:

Involved in nucleoside diphosphate kinase activity

Specific function:

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate

Gene Name:

ndk

Locus Tag:

PA3807

Molecular weight:

15.6 kDa

Reactions

General function:

Involved in DNA binding

Specific function:

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA

Gene Name:

dnaN

Locus Tag:

PA0002

Molecular weight:

40.7 kDa

Reactions

General function:

Involved in [formate-C-acetyltransferase]-activating enzyme activity

Specific function:

Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine

Gene Name:

nrdG

Locus Tag:

PA1919

Molecular weight:

25.7 kDa

General function:

Involved in magnesium ion binding

Specific function:

ATP + pyruvate = ADP + phosphoenolpyruvate

Gene Name:

pykF

Locus Tag:

PA1498

Molecular weight:

51.5 kDa

Reactions

General function:

Involved in nucleoside-triphosphate diphosphatase activity

Specific function:

Specific function unknown

Gene Name:

mazG

Locus Tag:

PA0935

Molecular weight:

31.2 kDa

Reactions

General function:

Involved in 3'-5' exonuclease activity

Specific function:

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase

Gene Name:

dnaE

Locus Tag:

PA3640

Molecular weight:

130.9 kDa

Reactions

General function:

Involved in magnesium ion binding

Specific function:

ATP + pyruvate = ADP + phosphoenolpyruvate

Gene Name:

pykA

Locus Tag:

PA4329

Molecular weight:

52.3 kDa

Reactions

General function:

Involved in DNA binding

Specific function:

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA

Gene Name:

holA

Locus Tag:

PA3989

Molecular weight:

37.4 kDa

Reactions

General function:

Involved in DNA binding

Specific function:

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity

Gene Name:

holB

Locus Tag:

PA2961

Molecular weight:

35.7 kDa

Reactions

General function:

Involved in catalytic activity

Specific function:

2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H(2)O = ribonucleoside triphosphate + thioredoxin

Gene Name:

nrdD

Locus Tag:

PA1920

Molecular weight:

76.1 kDa

Reactions

General function:

Involved in DNA binding

Specific function:

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity

Gene Name:

holC

Locus Tag:

PA3832

Molecular weight:

16.1 kDa

Reactions

General function:

Involved in ATP binding

Specific function:

Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. This small ubiquitous enzyme involved in the energy metabolism and nucleotide synthesis, is essential for maintenance and cell growth

Gene Name:

adk

Locus Tag:

PA3686

Molecular weight:

23.1 kDa

Reactions