DNA polymerase III subunit epsilon (PA1816)

Identification
Name: DNA polymerase III subunit epsilon
Synonyms: Not Available
Gene Name: dnaQ
Enzyme Class:
Biological Properties
General Function: Involved in DNA binding
Specific Function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions:
Thumb+DNA ↔ Thumb+DNA
dATP + DNA ↔ Pyrophosphate + DNA
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Thumb+DNA ↔ Thumb+DNA
dGTP + DNA ↔ Pyrophosphate + DNA
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Thumb+DNA ↔ Thumb+DNA
dCTP + DNA ↔ Pyrophosphate + DNA
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Thumb+DNA ↔ Thumb+DNA
Thymidine 5'-triphosphate + DNA ↔ Pyrophosphate + DNA
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Deoxynucleoside triphosphate+DNA ↔ Thumb
Deoxynucleoside triphosphate + DNA ↔ Pyrophosphate
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SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
DNAn ? a nucleoside monophosphate
DNAn ? a nucleoside monophosphate
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Complex Reactions:
Deoxynucleoside triphosphate+DNA(n) → Thumb+DNA(n+1)
Deoxynucleoside triphosphate + DNA(n) → Pyrophosphate + DNA(n+1)
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Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000412dATPMetaboCard
PAMDB000219dCTPMetaboCard
PAMDB000389dGTPMetaboCard
PAMDB000633PyrophosphateMetaboCard
PAMDB000346Thymidine 5'-triphosphateMetaboCard
GO Classification:
Component
cell part
intracellular
Function
binding
catalytic activity
DNA binding
DNA polymerase activity
DNA-directed DNA polymerase activity
exonuclease activity
hydrolase activity
hydrolase activity, acting on ester bonds
nuclease activity
nucleic acid binding
nucleotidyltransferase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
cellular macromolecule metabolic process
DNA metabolic process
DNA replication
macromolecule metabolic process
metabolic process
Gene Properties
Locus tag: PA1816
Strand: +
Entrez Gene ID: 877654
Accession: NP_250507.1
GI: 15597013
Sequence start: 1973470
Sequence End: 1974210
Sequence Length: 740
Gene Sequence: 
>PA1816
ATGCGTAGCGTCGTACTGGATACCGAAACCACCGGCATGCCGGTGACCGATGGTCACCGGATCATCGAGATCGGCTGTGTCGAGCTGGAGGGGCGCCGCCTGACCGGTCGCCACTTCCACGTCTACCTGCAACCCGATCGCGAGGTCGACGAAGGGGCGATCGCCGTCCACGGCATCACCAACGAATACCTGAAGGACAAGCCGCGCTTCCGCGAGGTCGCCAACGATTTCTTCGAATTCATCCGCGGCGCCCAGCTGATCATCCACAACGCGGCGTTCGATATCGGCTTCATCAACAACGAGTTCGCCCTGCTGGGCCAGCAGGACCGCTCGGACGTGACCGAGTACTGCTCGGTGCTGGATACCCTGCTGATGGCCCGCGAGCGCCATCCGGGCCAGCGCAACAACCTCGATGCGTTGTGCAAGCGCTACGGCGTGGACAACTCCGGTCGCGACCTGCACGGCGCGTTGCTCGACGCCGAGATCCTCGCCGACGTCTACCTGGCGATGACCGGCGGCCAGACCAGCCTGTCGCTGGCCGGCAGCGGCGCGGAAGGCGACGGCAGCGGCCGGCCGATGGTCAGCCCGATCCGTCGGCTCGATCCGGCGCGGGTAGCCACCCCGGTGCTGCGCGCCAACGCCGAAGAGCTGGCTGCGCATGCGGCGCGGCTGGCGGTGATCGAGAAGTCGGCAGGTGGTCCGTCACTCTGGGCGCAACTGGAGGCGCCGGTCGGCGAATAG
Protein Properties
Protein Residues: 246
Protein Molecular Weight: 26.8 kDa
Protein Theoretical pI: 5.02
Hydropathicity (GRAVY score): -0.205
Charge at pH 7 (predicted): -9.16
Protein Sequence: 
>PA1816
MRSVVLDTETTGMPVTDGHRIIEIGCVELEGRRLTGRHFHVYLQPDREVDEGAIAVHGITNEYLKDKPRFREVANDFFEFIRGAQLIIHNAAFDIGFINNEFALLGQQDRSDVTEYCSVLDTLLMARERHPGQRNNLDALCKRYGVDNSGRDLHGALLDAEILADVYLAMTGGQTSLSLAGSGAEGDGSGRPMVSPIRRLDPARVATPVLRANAEELAAHAARLAVIEKSAGGPSLWAQLEAPVGE
References
External Links:
Resource Link
Genome ID: PA1816
Entrez Gene ID: 877654
NCBI Protein ID: 15597013
General Reference: PaperBLAST - Find papers about PA1816 and its homologs