Identification |
Name: |
DNA polymerase III subunit delta' |
Synonyms: |
Not Available |
Gene Name: |
holB |
Enzyme Class: |
|
Biological Properties |
General Function: |
Involved in DNA binding |
Specific Function: |
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity |
Cellular Location: |
Cytoplasmic |
KEGG Pathways: |
|
KEGG Reactions: |
|
| + | DNA | ↔ | | + | DNA |
| | |
| + | DNA | ↔ | | + | DNA |
| | |
| + | DNA | ↔ | | + | DNA |
| | |
| + | DNA | ↔ | | + | DNA |
| | |
Deoxynucleoside triphosphate | + | DNA | ↔ | |
| |
|
SMPDB Reactions: |
Not Available |
PseudoCyc/BioCyc Reactions: |
|
| + | DNA | ↔ | | + | DNA |
| | |
| + | DNA | ↔ | | + | DNA |
| | |
| + | DNA | ↔ | | + | DNA |
| | |
| + | DNA | ↔ | | + | DNA |
| | |
Deoxynucleoside triphosphate | + | DNA(n) | → | | + | DNA(n+1) |
| | |
Deoxynucleoside triphosphate | + | DNA | ↔ | |
| |
|
Complex Reactions: |
|
Deoxynucleoside triphosphate | + | DNA(n) | → | | + | DNA(n+1) |
| |
|
Transports: |
Not Available |
Metabolites: |
|
GO Classification: |
Component |
---|
DNA polymerase complex | DNA polymerase III complex | macromolecular complex | protein complex | Function |
---|
3'-5' exonuclease activity | binding | catalytic activity | DNA binding | DNA polymerase activity | DNA-directed DNA polymerase activity | exonuclease activity | hydrolase activity | hydrolase activity, acting on ester bonds | nuclease activity | nucleic acid binding | nucleotidyltransferase activity | transferase activity | transferase activity, transferring phosphorus-containing groups | Process |
---|
cellular macromolecule metabolic process | DNA metabolic process | DNA replication | macromolecule metabolic process | metabolic process |
|
Gene Properties |
Locus tag: |
PA2961 |
Strand: |
- |
Entrez Gene ID: |
880379 |
Accession: |
NP_251651.1 |
GI: |
15598157 |
Sequence start: |
3320064 |
Sequence End: |
3321050 |
Sequence Length: |
986 |
Gene Sequence: |
>PA2961
ATGGCTGATATCTATCCCTGGCAGCAGGCGCTCTGGAGCCAACTGGGCGGCCGCGCCCAGCACGCCCACGCCTATCTGCTCTACGGTCCCGCCGGGATCGGTAAGCGTGCCCTGGCCGAGCATTGGGCCGCCCAACTGCTCTGCCAGCGGCCTGCCGCCGCTGGCGCATGCGGCGAGTGCAAGGCCTGCCAGTTGCTGGCCGCCGGTACCCATCCGGACTACTTCGTGCTGGAGCCGGAGGAGGCGGAGAAACCGATCCGGGTCGATCAGGTCCGCGACCTGGTTGGCTTCGTGGTGCAGACCGCGCAACTGGGCGGGCGCAAGGTCGTGTTGCTCGAACCCGCCGAGGCGATGAACGTGAACGCCGCCAACGCCCTGTTGAAAAGCCTTGAAGAGCCGTCGGGCGATACTGTGCTGCTGCTGATCAGCCACCAGCCCAGCCGCCTGTTGCCGACCATCAAGAGCCGCTGCGTGCAGCAGGCCTGCCCTTTGCCGGGCGCGGCGGCGAGTCTGGAATGGCTGGCGCGGGCCCTGCCCGACGAGCCGGCCGAGGCCCTGGAGGAACTGTTGGCGCTTTCCGGCGGCTCGCCGCTCACCGCCCAGCGCCTGCACGGCCAGGGCGTGCGCGAGCAGCGCGCGCAGGTGGTCGAGGGGGTGAAGAAGCTGCTCAAGCAGCAGATCGCCGCCAGCCCACTGGCCGAAAGCTGGAACAGCGTGCCGTTGCCATTGCTCTTCGACTGGTTCTGCGACTGGACGCTGGGCATCCTGCGCTACCAGTTGACCCACGACGAGGAGGGGCTGGGGTTGGCCGACATGCGCAAGGTGATCCAGTACCTGGGCGACAAATCCGGGCAGGCCAAGGTGCTGGCCATGCAGGACTGGCTGCTGCAACAGCGGCAGAAAGTGTTGAACAAGGCCAACCTCAACCGTGTCCTGCTTCTCGAAGCCCTGCTGGTGCAGTGGGCAAGCCTGCCCGGGCCGGGCTAG |
Protein Properties |
Protein Residues: |
328 |
Protein Molecular Weight: |
35.7 kDa |
Protein Theoretical pI: |
6.62 |
Hydropathicity (GRAVY score): |
-0.027 |
Charge at pH 7 (predicted): |
-1.53 |
Protein Sequence: |
>PA2961
MADIYPWQQALWSQLGGRAQHAHAYLLYGPAGIGKRALAEHWAAQLLCQRPAAAGACGECKACQLLAAGTHPDYFVLEPEEAEKPIRVDQVRDLVGFVVQTAQLGGRKVVLLEPAEAMNVNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCVQQACPLPGAAASLEWLARALPDEPAEALEELLALSGGSPLTAQRLHGQGVREQRAQVVEGVKKLLKQQIAASPLAESWNSVPLPLLFDWFCDWTLGILRYQLTHDEEGLGLADMRKVIQYLGDKSGQAKVLAMQDWLLQQRQKVLNKANLNRVLLLEALLVQWASLPGPG |
References |
External Links: |
|
General Reference: |
PaperBLAST - Find papers about PA2961 and its homologs
|