| Identification |
| Name: |
DNA polymerase III subunit beta |
| Synonyms: |
Not Available |
| Gene Name: |
dnaN |
| Enzyme Class: |
|
| Biological Properties |
| General Function: |
Involved in DNA binding |
| Specific Function: |
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA |
| Cellular Location: |
Cytoplasm |
| KEGG Pathways: |
|
| KEGG Reactions: |
|
 | + | DNA | ↔ |  | + | DNA |
| | |
 | + | DNA | ↔ | | + | DNA |
| | |
 | + | DNA | ↔ | | + | DNA |
| | |
 | + | DNA | ↔ | | + | DNA |
| | |
Deoxynucleoside triphosphate | + | DNA | ↔ | |
| |
|
| SMPDB Reactions: |
Not Available |
| PseudoCyc/BioCyc Reactions: |
|
| + | DNA | ↔ | | + | DNA |
| | |
| + | DNA | ↔ | | + | DNA |
| | |
| + | DNA | ↔ | | + | DNA |
| | |
| + | DNA | ↔ | | + | DNA |
| | |
Deoxynucleoside triphosphate | + | DNA(n) | → | | + | DNA(n+1) |
| | |
Deoxynucleoside triphosphate | + | DNA | ↔ | |
| |
|
| Complex Reactions: |
|
Deoxynucleoside triphosphate | + | DNA(n) | → | | + | DNA(n+1) |
| |
|
| Transports: |
Not Available |
| Metabolites: |
|
| GO Classification: |
| Component |
|---|
| DNA polymerase complex | | DNA polymerase III complex | | macromolecular complex | | protein complex | | Function |
|---|
| 3'-5' exonuclease activity | | binding | | catalytic activity | | DNA binding | | DNA polymerase activity | | DNA-directed DNA polymerase activity | | exonuclease activity | | hydrolase activity | | hydrolase activity, acting on ester bonds | | nuclease activity | | nucleic acid binding | | nucleotidyltransferase activity | | transferase activity | | transferase activity, transferring phosphorus-containing groups | | Process |
|---|
| cellular macromolecule metabolic process | | DNA metabolic process | | DNA replication | | macromolecule metabolic process | | metabolic process |
|
| Gene Properties |
| Locus tag: |
PA0002 |
| Strand: |
+ |
| Entrez Gene ID: |
879244 |
| Accession: |
NP_064722.1 |
| GI: |
15595200 |
| Sequence start: |
2056 |
| Sequence End: |
3159 |
| Sequence Length: |
1103 |
| Gene Sequence: |
>PA0002
ATGCATTTCACCATTCAACGCGAAGCCCTGTTGAAACCGCTGCAACTGGTCGCCGGCGTCGTGGAACGCCGCCAGACATTGCCGGTTCTCTCCAACGTCCTGCTGGTGGTCGAAGGCCAGCAACTGTCGCTGACCGGCACCGACCTCGAAGTCGAGCTGGTTGGTCGCGTGGTACTGGAAGATGCCGCCGAACCCGGCGAGATCACCGTACCGGCGCGCAAGCTGATGGACATCTGCAAGAGCCTGCCGAACGACGTGCTGATCGACATCCGTGTCGAAGAGCAGAAACTTCTGGTGAAGGCCGGGCGTAGCCGCTTCACCCTGTCCACCCTGCCGGCCAACGATTTCCCCACCGTAGAGGAAGGTCCCGGCTCGCTGAACTTCAGCATTGCCCAGAGCAAGCTGCGTCGCCTGATCGACCGCACCAGCTTCGCCATGGCCCAGCAGGACGTGCGTTACTACCTCAACGGCATGCTGCTGGAAGTGAACGGCGGCACCCTGCGCTCCGTCGCCACCGACGGCCACCGACTGGCCATGTGCTCGCTGGATGCGCAGATCCCGTCGCAGGACCGCCACCAGGTGATCGTGCCGCGCAAAGGCATCCTCGAACTGGCTCGTCTGCTCACCGAGCAGGACGGCGAAGTCGGCATCGTCCTGGGCCAGCACCATATCCGTGCCACCACTGGCGAATTCACCTTCACTTCGAAGCTGGTGGACGGCAAGTTCCCGGACTACGAGCGTGTACTGCCGCGCGGTGGCGACAAGCTGGTGGTCGGTGACCGCCAGCAACTGCGCGAAGCCTTCAGCCGTACCGCGATCCTCTCCAACGAGAAGTACCGCGGCATTCGCCTGCAGCTTTCCAACGGTTTGCTGAAAATCCAGGCGAACAACCCGGAGCAGGAAGAGGCCGAGGAAGAAGTGCAGGTCGAGTACAACGGCGGCAACCTGGAGATAGGCTTCAACGTCAGTTACCTGCTCGACGTGCTGGGTGTGATCGGTACCGAGCAGGTCCGCTTCATCCTTTCCGATTCCAACAGCAGCGCCCTGGTCCACGAGGCCGACAATGACGATTCTGCCTATGTCGTCATGCCGATGCGCCTCTAA |
| Protein Properties |
| Protein Residues: |
367 |
| Protein Molecular Weight: |
40.7 kDa |
| Protein Theoretical pI: |
4.89 |
| Hydropathicity (GRAVY score): |
-0.147 |
| Charge at pH 7 (predicted): |
-10.6 |
| Protein Sequence: |
>PA0002
MHFTIQREALLKPLQLVAGVVERRQTLPVLSNVLLVVEGQQLSLTGTDLEVELVGRVVLEDAAEPGEITVPARKLMDICKSLPNDVLIDIRVEEQKLLVKAGRSRFTLSTLPANDFPTVEEGPGSLNFSIAQSKLRRLIDRTSFAMAQQDVRYYLNGMLLEVNGGTLRSVATDGHRLAMCSLDAQIPSQDRHQVIVPRKGILELARLLTEQDGEVGIVLGQHHIRATTGEFTFTSKLVDGKFPDYERVLPRGGDKLVVGDRQQLREAFSRTAILSNEKYRGIRLQLSNGLLKIQANNPEQEEAEEEVQVEYNGGNLEIGFNVSYLLDVLGVIGTEQVRFILSDSNSSALVHEADNDDSAYVVMPMRL |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA0002 and its homologs
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