Identification |
Name: |
Galactitol-specific phosphotransferase enzyme IIB component |
Synonyms: |
- EIIB-Gat
- PTS system galactitol-specific EIIB component
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Gene Name: |
gatB |
Enzyme Class: |
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Biological Properties |
General Function: |
Involved in sugar:hydrogen symporter activity |
Specific Function: |
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in galactitol transport |
Cellular Location: |
Cytoplasm (Potential) |
KEGG Pathways: |
- Amino sugar and nucleotide sugar metabolism pae00520
- Ascorbate and aldarate metabolism pae00053
- Fructose and mannose metabolism pae00051
- Galactose metabolism pae00052
- Glycolysis / Gluconeogenesis pae00010
- Metabolic pathways pae01100
- Microbial metabolism in diverse environments pae01120
- Pentose phosphate pathway pae00030
- Starch and sucrose metabolism pae00500
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KEGG Reactions: |
|
![Thumb](/molecules/PAMDB000040thumb.png) | + | Protein N(pi)-phospho-L-histidine | ↔ | ![Thumb](/molecules/PAMDB000996thumb.png) | + | Protein histidine |
| | |
Protein N(pi)-phospho-L-histidine | + | Sugar | ↔ | Protein histidine | + | ![Thumb](http://moldb.wishartlab.com/molecules//thumb.png) |
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SMPDB Reactions: |
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![Thumb](/molecules/PAMDB000040thumb.png) | + | HPr - phosphorylated | → | Galactose 1-phosphate | + | HPr | + | ![Thumb](/molecules/PAMDB000556thumb.png) |
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PseudoCyc/BioCyc Reactions: |
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Complex Reactions: |
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Protein EIIB N(pi)-phospho-L-histidine/cysteine | + | ![Thumb](/molecules/PAMDB000109thumb.png) | → | protein EIIB | + | sugar phosphate |
| Protein EIIB N(pi)-phospho-L-histidine/cysteine + Sucrose → protein EIIB + sugar phosphate ReactionCard |
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Transports: |
Not Available |
Metabolites: |
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GO Classification: |
Function |
---|
carbohydrate transmembrane transporter activity | cation transmembrane transporter activity | cation:sugar symporter activity | ion transmembrane transporter activity | protein-N(PI)-phosphohistidine-sugar phosphotransferase activity | solute:cation symporter activity | substrate-specific transmembrane transporter activity | sugar:hydrogen symporter activity | transmembrane transporter activity | transporter activity | Process |
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carbohydrate transport | establishment of localization | phosphoenolpyruvate-dependent sugar phosphotransferase system | transport |
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Gene Properties |
Locus tag: |
PA4484 |
Strand: |
+ |
Entrez Gene ID: |
881181 |
Accession: |
NP_253174.1 |
GI: |
15599680 |
Sequence start: |
5015535 |
Sequence End: |
5016980 |
Sequence Length: |
1445 |
Gene Sequence: |
>PA4484
ATGCAATGGGAAACCGTGATCGGGCTGGAAATCCACGCACAGCTCGCCACCCAATCGAAGATCTTCTCCGGCAGCTCGACCGCCTTCGGCGCCGCGCCGAATACCCAAGCCAGCCTGGTCGACCTGGCCATGCCGGGCACCCTGCCGGTGCTCAACGAGGAGGCCGTACGCATGGCCTGCCTGTTCGGCCTGGCGATCGACGCACGGATCGACCGGCAGAACGTGTTCGCCCGCAAGAACTACTTCTACCCCGACCTGCCGAAGGGCTACCAGACCAGCCAGATGGACCATCCTATCGTCGGCAAGGGCCATCTCGACATCACCCTGGAAGACGGCACCACCAAGCGCATCGGCATCACCCGCGCGCACCTGGAGGAGGACGCCGGCAAGAGCCTGCACGAAGACTTCCAGGGCATGAGCGGCATCGACCTGAACCGCGCCGGCACGCCGTTGCTGGAGATCGTTTCCGAGCCGGACATCCGCAGCGCCAAGGAAGCCGTGGCCTACGTCAAGGCGATCCACGCCCTGGTGCGCTACCTGGGCATCTGCGACGGCAACATGGCCGAGGGCTCGCTGCGCTGCGACTGCAACGTCTCGGTACGACCGAAGGGCCAGGCCGAATTCGGCACCCGCGCCGAGATCAAGAACGTCAACTCCTTCCGCTTCATCGAGAAGGCGATCAACCACGAGATCCAGCGCCAGATCGAGCTGATCGAGGACGGCGGCAAGGTAGTCCAGGAAACCCGCCTGTACGACCCGAACAAGGACGAGACCCGCTCCATGCGCGGCAAGGAAGAAGCCAACGACTACCGTTACTTCCCCTGTCCCGACCTGCTGCCGGTGGTCATCGAGCCCGAGTACCTGGCGAAGCTGCGCGAGCAACTGCCGGAACTGCCGGTGCAGAAGCGCGAACGCTTCGAGAGCCAGTACGGCCTGTCCGCCTACGATGCCAGCGTGCTGTCCGCCAGCCGCGAGATGGCCGACTACTTCGAGAAGGTCCAGGGCATCTGCGGCGACGCCAAGCTGGCGGCCAACTGGGTGATGGTCGAGCTGGGCAGCCTGCTCAACAAGGACGGCCTGGAGATCGAGCAGTCCCCGGTGTCCGCCGAGCAACTGGGCGGCATGATCCTGCGCATCAAGGACAACACCATCTCCGGCAAGCTCGCCAAGATGGTCTTCGAAGCCATGGCCAACGGCGAGGGTTCCGCCGACCAGATCATCGAGGCCAAGGGCCTGAAGCAGGTCACCGACAGTGGCGCCATCGAGAAGATGCTCGACGAGGTGCTGGCGGCCAACGCCGAGCAGGTCGAGCAGTACCGCGCTGCCGACGAGGCCAAGCGCGGCAAGATGTTCGGCTTCTTCGTCGGCCAGGCGATGAAGGCCTCGAAAGGCAAGGCCAACCCGCAGCAGGTGAACGAGTTGCTGAAGAAAAAGCTCGAAGCGTGA |
Protein Properties |
Protein Residues: |
481 |
Protein Molecular Weight: |
53.1 kDa |
Protein Theoretical pI: |
5.05 |
Hydropathicity (GRAVY score): |
-0.347 |
Charge at pH 7 (predicted): |
-11.47 |
Protein Sequence: |
>PA4484
MQWETVIGLEIHAQLATQSKIFSGSSTAFGAAPNTQASLVDLAMPGTLPVLNEEAVRMACLFGLAIDARIDRQNVFARKNYFYPDLPKGYQTSQMDHPIVGKGHLDITLEDGTTKRIGITRAHLEEDAGKSLHEDFQGMSGIDLNRAGTPLLEIVSEPDIRSAKEAVAYVKAIHALVRYLGICDGNMAEGSLRCDCNVSVRPKGQAEFGTRAEIKNVNSFRFIEKAINHEIQRQIELIEDGGKVVQETRLYDPNKDETRSMRGKEEANDYRYFPCPDLLPVVIEPEYLAKLREQLPELPVQKRERFESQYGLSAYDASVLSASREMADYFEKVQGICGDAKLAANWVMVELGSLLNKDGLEIEQSPVSAEQLGGMILRIKDNTISGKLAKMVFEAMANGEGSADQIIEAKGLKQVTDSGAIEKMLDEVLAANAEQVEQYRAADEAKRGKMFGFFVGQAMKASKGKANPQQVNELLKKKLEA |
References |
External Links: |
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General Reference: |
PaperBLAST - Find papers about PA4484 and its homologs
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