Identification
Name: Argininosuccinate synthase
Synonyms:
  • Citrulline--aspartate ligase
Gene Name: argG
Enzyme Class:
Biological Properties
General Function: Involved in argininosuccinate synthase activity
Specific Function: ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate
Cellular Location: Cytoplasm (Probable)
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+ThumbThumb+Thumb+Thumb+Thumb
Thumb+Thumb+ThumbThumb+Thumb+Thumb
SMPDB Reactions:
Thumb+Thumb+L-Aspartic acid+ThumbPyrophosphate+Thumb+Thumb
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+ThumbThumb+Thumb+Thumb+Thumb
Thumb+Thumb+ThumbThumb+Thumb+Thumb
Thumb+Thumb+L-Aspartic acid+ThumbPyrophosphate+Thumb+Thumb
Thumb
L-aspartate + L-citrulline + ATP → L-arginino-succinate + AMP + diphosphate + H+
ReactionCard
PAMDB120499+PAMDB110670+PAMDB110477PAMDB001633+PAMDB120244+PAMDB110478+PAMDB110246
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000014Adenosine monophosphateMetaboCard
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000224Argininosuccinic acidMetaboCard
PAMDB000198CitrullineMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000080L-Aspartic acidMetaboCard
PAMDB000633PyrophosphateMetaboCard
GO Classification:
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
argininosuccinate synthase activity
ATP binding
binding
catalytic activity
ligase activity
ligase activity, forming carbon-nitrogen bonds
nucleoside binding
purine nucleoside binding
Process
arginine biosynthetic process
arginine metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
cellular metabolic process
glutamine family amino acid metabolic process
metabolic process
Gene Properties
Locus tag: PA3525
Strand: -
Entrez Gene ID: 878872
Accession: NP_252215.1
GI: 15598721
Sequence start: 3944662
Sequence End: 3945879
Sequence Length: 1217
Gene Sequence:
>PA3525
ATGGCGGATGTGAAGAAGGTAGTCCTGGCGTATTCCGGCGGCCTGGATACCTCGGTAATTCTGAAGTGGTTGCAAGATACCTATAACTGCGAAGTGGTGACCTTCACCGCCGACCTCGGCCAGGGCGAGGAAGTCGAACCGGCTCGCGCCAAGGCCCGCGCGATGGGCGTCAAGGAAATCTACATCGACGACCTGCGCGAAGAATTCGTCCGCGACTTCGTCTACCCGATGTTCCGCGCCAACACCGTCTACGAAGGCGAGTACCTGCTGGGCACCTCCATCGCTCGTCCGCTGATCGCCAAGCGCCTGATCGAGATCGCCAACGAGACCGGCGCCGACGCCATCTCCCACGGCGCCACCGGCAAGGGCAACGACCAGGTCCGCTTCGAGCTGGGCGCCTACGCGCTGAAGCCCGGCGTCAAGGTGATCGCGCCCTGGCGCGAGTGGGACCTGCTGTCCCGCGAGAAGCTGATGGACTATGCCGAGAAGCACGGCATCCCGATCGAGCGCCACGGCAAGAAGAAGTCGCCGTACTCGATGGACGCCAACCTCCTGCATATCTCCTACGAAGGGGGCGTGCTGGAAGATACCTGGACCGAGCACGAAGAAGACATGTGGAAGTGGACCGCTTCCCCGGAAAACGCGCCGGACACCCCGACCTACATCGAGCTGACCTACCGCAAGGGCGACATCGTCGCCATCGACGGCAAGGACATGACCCCGGCCGAGGTGCTCACCGAGCTGAACCGCGTCGGCGGGATCAACGGCATCGGCCGCCTCGACATCGTCGAGAACCGCTATGTCGGCATGAAGTCCCGTGGCTGCTACGAGACCCCCGGCGGCACCATCATGCTCAAGGCCCACCGCGCCATCGAGTCGATCACCCTGGACCGCGAAGTGGCCCACCTGAAAGACGAGCTGATGCCCAAGTACGCCAGCCTGATCTACACCGGCTACTGGTGGAGCCCGGAGCGCCTGATGCTGCAGCAGATGATCGACGCCTCGCAGGTCAACGTGAACGGCGTAGTGCGCCTGAAGCTGTACAAGGGCAACGTCGTGGTGGTGGGCCGCAAGTCCGACGACTCGCTGTTCGACGCCAACATCGCGACCTTCGAGGAAGACGGCGGCGCCTACAACCAGGCCGATGCCGCGGGCTTCATCAAGCTCAACGCGCTGCGCATGCGCATCGCCGCGAACAAGGGCCGCACGCTGTCCTGA
Protein Properties
Protein Residues: 405
Protein Molecular Weight: 45.3 kDa
Protein Theoretical pI: 5.25
Hydropathicity (GRAVY score): -0.319
Charge at pH 7 (predicted): -8.36
Protein Sequence:
>PA3525
MADVKKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKARAMGVKEIYIDDLREEFVRDFVYPMFRANTVYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDYAEKHGIPIERHGKKKSPYSMDANLLHISYEGGVLEDTWTEHEEDMWKWTASPENAPDTPTYIELTYRKGDIVAIDGKDMTPAEVLTELNRVGGINGIGRLDIVENRYVGMKSRGCYETPGGTIMLKAHRAIESITLDREVAHLKDELMPKYASLIYTGYWWSPERLMLQQMIDASQVNVNGVVRLKLYKGNVVVVGRKSDDSLFDANIATFEEDGGAYNQADAAGFIKLNALRMRIAANKGRTLS
References
External Links:
Resource Link
Genome ID: PA3525
Entrez Gene ID: 878872
NCBI Protein ID: 15598721
General Reference: PaperBLAST - Find papers about PA3525 and its homologs