Reaction 21857

Reaction Details
Reaction: Thumb
L-glutamine + UTP + ATP + H2O → ADP + CTP + L-glutamate + phosphate + 2 H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:CTPSYN-RXN
References:
  • Levitzki A, Koshland DE (1972). "Ligand-induced dimer-to-tetramer transformation in cytosine triphosphate synthetase." Biochemistry 11(2);247-53. PMID: 4550560
  • Lewis DA, Villafranca JJ (1989). "Investigation of the mechanism of CTP synthetase using rapid quench and isotope partitioning methods." Biochemistry 28(21);8454-9. PMID: 2532543
  • Lieberman I (1956). "Enzymatic amination of uridine triphosphate to cytidine triphosphate." J Biol Chem 222(2);765-75. PMID: 13367044
  • von der Saal W, Anderson PM, Villafranca JJ (1985). "Mechanistic investigations of Escherichia coli cytidine-5'-triphosphate synthetase. Detection of an intermediate by positional isotope exchange experiments." J Biol Chem 260(28);14993-7. PMID: 2933396
  • Wadskov-Hansen SL, Willemoes M, Martinussen J, Hammer K, Neuhard J, Larsen S (2001). "Cloning and verification of the Lactococcus lactis pyrG gene and characterization of the gene product, CTP synthase." J Biol Chem 276(41);38002-9. PMID: 11500486