glutamine amidotransferase (PA5142)

Identification
Name: glutamine amidotransferase
Synonyms: Not Available
Gene Name: hisH1
Enzyme Class: Not Available
Biological Properties
General Function: histidine biosynthetic process
Specific Function: imidazoleglycerol-phosphate synthase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
  • guanosine ribonucleotides de novo biosynthesis PWY-7221
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
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    XMP + ammonium + ATP = GMP + AMP + diphosphate + 2 H+
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    XMP + L-glutamine + ATP + H2O → L-glutamate + GMP + AMP + diphosphate + 2 H+
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    L-glutamate + NADP+ + H2O → ammonium + 2-oxoglutarate + NADPH + H+
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    L-glutamine + H2O → L-glutamate + ammonium
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    2 L-glutamate + NADP+ ← L-glutamine + 2-oxoglutarate + NADPH + H+
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    phenazine-1-carboxylate + L-glutamate + ATP → phenazine-1-carboxamide + L-glutamate + AMP + diphosphate
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    2 ATP + L-glutamine + hydrogen carbonate + H2O → L-glutamate + carbamoyl-phosphate + 2 ADP + phosphate + 2 H+
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    2 ATP + hydrogen carbonate + ammonium → 2 ADP + carbamoyl-phosphate + phosphate + 2 H+
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    ATP + UTP + ammonium → ADP + CTP + phosphate + 2 H+
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    L-glutamine + UTP + ATP + H2O → ADP + CTP + L-glutamate + phosphate + 2 H+
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    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Component
    imidazoleglycerol-phosphate synthase complex
    Function
    imidazoleglycerol-phosphate synthase activity
    Process
    histidine biosynthetic process
    Gene Properties
    Locus tag: PA5142
    Strand: -
    Entrez Gene ID: 878788
    Accession: NP_253829.1
    GI: 15600335
    Sequence start: 5790445
    Sequence End: 5791086
    Sequence Length: 641
    Gene Sequence: 
    >PA5142
GTGATGCAGACGGTAGCCGTGATCGACTACGGCATGGGCAACCTGCACTCGGTGGCCAAGGCCCTTGAGCACGTCGGTGCCGGCCGGGTGCTGGTTAGCAGCGACGCGGCGGTGATCCGCGAGGCCGACCGGGTGGTGTTCCCCGGGGTTGGCGCGATCCGCGACTGCATGGCCGAGATCCGCCGCCTGGGCTTCGACGCCCTGGTCCGCGAGGTCAGCCAGGACCGCCCGTTCCTCGGCATCTGCGTCGGCATGCAGGCATTGCTGGAGCGCAGCGAGGAGAACGACGGGGTCGACTGCATCGGTCTGTTCCCCGGCCAGGTGCGCTTCTTCGGCAAGGACCTGCACGAAGCCGGCGAGCACCTGAAGGTGCCGCACATGGGCTGGAACCAGGTGAGCCAGGCGGTGGAGCACCCGTTGTGGCACGAGATTCCCGACCAGGCGCGCTTCTACTTCGTGCACAGCTATTACATCGAGGCCGGTAACCCGCGCCAGGTGGTGGGGCACGGGCACTACGGCGTCGATTTCGCCGCCGCGCTGGCCGAAGGCTCGCGTTTCGCCGTGCAGTTCCACCCGGAAAAGAGCCATACCCACGGCCTGCAACTGCTGCAGAACTTCGTGGCCTGGGACGGGCGCTGGTAG
    Protein Properties
    Protein Residues: 213
    Protein Molecular Weight: 23.7 kDa
    Protein Theoretical pI: 6.31
    Hydropathicity (GRAVY score): -0.081
    Charge at pH 7 (predicted): -4.97
    Protein Sequence: 
    >PA5142
MMQTVAVIDYGMGNLHSVAKALEHVGAGRVLVSSDAAVIREADRVVFPGVGAIRDCMAEIRRLGFDALVREVSQDRPFLGICVGMQALLERSEENDGVDCIGLFPGQVRFFGKDLHEAGEHLKVPHMGWNQVSQAVEHPLWHEIPDQARFYFVHSYYIEAGNPRQVVGHGHYGVDFAAALAEGSRFAVQFHPEKSHTHGLQLLQNFVAWDGRW
    References
    External Links:
    Resource Link
    Genome ID: PA5142
    Entrez Gene ID: 878788
    NCBI Protein ID: 15600335
    General Reference: PaperBLAST - Find papers about PA5142 and its homologs