Reaction Details
Reaction: Thumb
2 L-glutamate + NADP+ ← L-glutamine + 2-oxoglutarate + NADPH + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:GLUTAMATESYN-RXN
References:
  • Miller RE, Stadtman ER (1972). "Glutamate synthase from Escherichia coli. An iron-sulfide flavoprotein." J Biol Chem 247(22);7407-19. PMID: 4565085
  • Ravasio S, Curti B, Vanoni MA (2001). "Determination of the midpoint potential of the FAD and FMN flavin cofactors and of the 3Fe-4S cluster of glutamate synthase." Biochemistry 40(18);5533-41. PMID: 11331018
  • Tempest DW, Meers JL, Brown CM (1970). "Synthesis of glutamate in Aerobacter aerogenes by a hitherto unknown route." Biochem J 117(2);405-7. PMID: 5420057
  • Vanoni MA, Curti B (1999). "Glutamate synthase: a complex iron-sulfur flavoprotein." Cell Mol Life Sci 55(4);617-38. PMID: 10357231