Reaction Details
Reaction: Thumb
L-glutamine + H2O → L-glutamate + ammonium
External Links:
PseudoCyc Reaction ID:GLUTAMIN-RXN
  • Lubkowski J, Wlodawer A, Ammon HL, Copeland TD, Swain AL (1994). "Structural characterization of Pseudomonas 7A glutaminase-asparaginase." Biochemistry 33(34);10257-65. PMID: 8068664
  • Ortlund E, Lacount MW, Lewinski K, Lebioda L (2000). "Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu." Biochemistry 39(6);1199-204. PMID: 10684596
  • Roberts J, Holcenberg JS, Dolowy WC (1972). "Isolation, crystallization, and properties of Achromobacteraceae glutaminase-asparaginase with antitumor activity." J Biol Chem 247(1);84-90. PMID: 5017769
  • Tanaka S, Robinson EA, Appella E, Miller M, Ammon HL, Roberts J, Weber IT, Wlodawer A (1988). "Structures of amidohydrolases. Amino acid sequence of a glutaminase-asparaginase from Acinetobacter glutaminasificans and preliminary crystallographic data for an asparaginase from Erwinia chrysanthemi." J Biol Chem 263(18);8583-91. PMID: 3379033