Pyridoxamine kinase (PA5516)

Identification
Name: Pyridoxamine kinase
Synonyms:
  • PM kinase
Gene Name: pdxY
Enzyme Class:
Biological Properties
General Function: Involved in pyridoxal kinase activity
Specific Function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine, but has negligible activity toward pyridoxal and pyridoxine as substrates
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Adenosine triphosphate + Pyridoxal ↔ ADP + Hydrogen ion + Pyridoxal 5'-phosphate
ReactionCard
Thumb+Thumb → Thumb+Thumb+Thumb
Adenosine triphosphate + Pyridoxine → ADP + Hydrogen ion + Pyridoxine 5'-phosphate
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Thumb+Thumb → Thumb+Thumb+Thumb
Adenosine triphosphate + Pyridoxamine → ADP + Hydrogen ion + Pyridoxamine 5'-phosphate
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + Pyridoxal ↔ ADP + Pyridoxal 5'-phosphate
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + Pyridoxine ↔ ADP + Pyridoxine 5'-phosphate
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + Pyridoxamine ↔ ADP + Pyridoxamine 5'-phosphate
ReactionCard
Thumb+Thumb → Thumb+Thumb+Thumb
Adenosine triphosphate + Pyridoxine → Hydrogen ion + ADP + Pyridoxine 5'-phosphate
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SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Adenosine triphosphate + Pyridoxal ↔ ADP + Hydrogen ion + Pyridoxal 5'-phosphate
ReactionCard
Thumb+Thumb → Thumb+Thumb+Thumb
Adenosine triphosphate + Pyridoxine → ADP + Hydrogen ion + Pyridoxine 5'-phosphate
ReactionCard
Thumb+Thumb → Thumb+Thumb+Thumb
Adenosine triphosphate + Pyridoxamine → ADP + Hydrogen ion + Pyridoxamine 5'-phosphate
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + Pyridoxamine ↔ ADP + Pyridoxamine 5'-phosphate
ReactionCard
Thumb+Thumb → Thumb+Thumb+Thumb
Adenosine triphosphate + Pyridoxine → Hydrogen ion + ADP + Pyridoxine 5'-phosphate
ReactionCard
Thumb+Thumb → Thumb+Thumb+Thumb
Adenosine triphosphate + Pyridoxal → Hydrogen ion + ADP + Pyridoxal 5'-phosphate
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Complex Reactions:
Thumb+Thumb → Thumb+Thumb
Adenosine triphosphate + Pyridoxal → ADP + Pyridoxal 5'-phosphate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000414PyridoxalMetaboCard
PAMDB000400Pyridoxal 5'-phosphateMetaboCard
PAMDB000384PyridoxamineMetaboCard
PAMDB000420Pyridoxamine 5'-phosphateMetaboCard
PAMDB000099PyridoxineMetaboCard
PAMDB000338Pyridoxine 5'-phosphateMetaboCard
GO Classification:
Function
catalytic activity
kinase activity
pyridoxal kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
metabolic process
pyridoxine biosynthetic process
pyridoxine metabolic process
small molecule metabolic process
vitamin B6 metabolic process
vitamin metabolic process
water-soluble vitamin metabolic process
Gene Properties
Locus tag: PA5516
Strand: +
Entrez Gene ID: 878628
Accession: NP_254203.1
GI: 15600709
Sequence start: 6208575
Sequence End: 6209441
Sequence Length: 866
Gene Sequence: 
>PA5516
ATGCCACGTACGCCCCACCTGCTCGCCATCCAGTCCCATGTGGTCTTCGGCCACGCCGGCAATGCCGCGGCGGTGTTCCCGATGCAGCGCATCGGAATCAACGTCTGGCCGTTGAACACGGTGCAATTCTCCAACCACACCCAGTACGGTCGATGGACCGGGCAGGTGCTGCCGCCGGAGCAGATTCCGGCGCTGGTGGACGGTATTGCCGGCATCGGCGAACTGGGCAACTGCGACGCGGTGCTGTCCGGCTATCTCGGCAGCGCCGCCCAGGGCCGCGCCATTCTCGATGTGGTGGCACGGATCAAACAGGCCAACCCTCGGGCGTTGTACCTCTGCGACCCGGTCATGGGCCACCCGGAAAAAGGCTGCATCGTGGCCCCGGAGGTCAGCGACTTCCTTCTGGAAGAAGCCGCCGCGGTCGCCGACTACCTGTGCCCCAACCAGTTGGAGCTGGACAGCTTCTGCGACCGCCAGCCGAACTCCCTCGCCGACTGCGTGGAAATGGCACGGAGCCTGCTGGCACGCGGTCCCAGGGCAATCCTGGTAAAGCACCTGAACTATCCGGGCAAGGCCGGCGACACCTTCGAGATGCTGCTGGTGGCCGCCGATCAGGCCTGGCACCTGCAACGCCCGCTGCTGGCCTTCCCGCGGCAACCGGTCGGAGTCGGCGACCTGGCCTCGGGGCTGTTCCTCTCTCGCCTGCTGCTCGGCGACGACCTGCGTAACGCCTTCGAATTCACCGGCGCCGCGGTCCATGAAGTGCTGCTGGAAACCCAGGCCTGCGGCAGCTACGAGCTGGAACTGGTGCGGGCGCAGGATCGGATCGCACACCCAAGGGTTCGTTTCGACGCAGTGCGCCTTTAG
Protein Properties
Protein Residues: 288
Protein Molecular Weight: 31.3 kDa
Protein Theoretical pI: 6.03
Hydropathicity (GRAVY score): 0.108
Charge at pH 7 (predicted): -5.05
Protein Sequence: 
>PA5516
MPRTPHLLAIQSHVVFGHAGNAAAVFPMQRIGINVWPLNTVQFSNHTQYGRWTGQVLPPEQIPALVDGIAGIGELGNCDAVLSGYLGSAAQGRAILDVVARIKQANPRALYLCDPVMGHPEKGCIVAPEVSDFLLEEAAAVADYLCPNQLELDSFCDRQPNSLADCVEMARSLLARGPRAILVKHLNYPGKAGDTFEMLLVAADQAWHLQRPLLAFPRQPVGVGDLASGLFLSRLLLGDDLRNAFEFTGAAVHEVLLETQACGSYELELVRAQDRIAHPRVRFDAVRL
References
External Links:
Resource Link
Genome ID: PA5516
Entrez Gene ID: 878628
NCBI Protein ID: 15600709
General Reference: PaperBLAST - Find papers about PA5516 and its homologs