Identification
Name: Malate:quinone oxidoreductase
Synonyms:
  • MQO
  • Malate dehydrogenase [quinone]
Gene Name: mqo
Enzyme Class:
Biological Properties
General Function: Involved in malate dehydrogenase (quinone) activity
Specific Function: (S)-malate + a quinone = oxaloacetate + reduced quinone
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
SMPDB Reactions:
L-Malic acid+Thumb+ThumbThumb+Thumb
PseudoCyc/BioCyc Reactions:
Thumb+a quinoneThumb+a quinol
L-Malic acid + a quinone → Oxalacetic acid + a quinol
ReactionCard
Complex Reactions:
Thumb+ThumbThumb+Thumb
Thumb+Menaquinone 8Thumb+Thumb
Thumb+a quinoneThumb+reduced quinone
L-Malic acid + a quinone → Oxalacetic acid + reduced quinone
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000308FADMetaboCard
PAMDB000293FADH2MetaboCard
PAMDB001640Hydrogen peroxideMetaboCard
PAMDB000459HydroquinoneMetaboCard
PAMDB000058L-Malic acidMetaboCard
PAMDB001653Menaquinol 8MetaboCard
PAMDB000092Oxalacetic acidMetaboCard
PAMDB000624OxygenMetaboCard
PAMDB003450QuinoneMetaboCard
PAMDB000237Ubiquinol-8MetaboCard
PAMDB001700Ubiquinone-8MetaboCard
GO Classification:
Function
catalytic activity
malate dehydrogenase (quinone) activity
malate dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on CH-OH group of donors
Process
acetyl-CoA catabolic process
acetyl-CoA metabolic process
cellular metabolic process
coenzyme metabolic process
cofactor metabolic process
metabolic process
oxidation reduction
tricarboxylic acid cycle
Gene Properties
Locus tag: PA3452
Strand: +
Entrez Gene ID: 879029
Accession: NP_252142.1
GI: 15598648
Sequence start: 3856749
Sequence End: 3858320
Sequence Length: 1571
Gene Sequence:
>PA3452
ATGAAAAAAATCTTATTGATGCTTTTGTGCGTCAGCGTGCTGGGTTGCTCCAAAAACAGCGTCGAATCGGAAAAACCGGTCGACGTGCTCCTGATCGGTGGCGGCATCATGAGCGCCACCCTGGGTACCTATCTGAACGAACTGGAACCAGGCTGGACCATCGAGATGGTCGAGCGCCTGGACAAGGTCGCCGAAGAAAGCTCCAACGGCTGGAACAACGCGGGCACCGGTCACTCGGCGTTCTGCGAACTGAACTACACCAGCGAGGCCGCGGACGGCTCGATGGATATCAGCAAGGCGGTGGCGATCAACGAGAACTTCGAGATCTCCAAGCAGTTCTGGGCCTACCAGGTCGACCGCAAGGTGCTGAACGATCCGAAGTCGTTCATCAACAACGTCCCGCACATGAGCTTCGTCTGGGGCGACGACAACGTCGCCTTCCTCAAGAAGCGCCACGCCGCCCTGCAGCACAGCTCGCTGTTCCGCGGCATGGAGTACTCGGAAGACCCCGAGCAGATCAAGCAGTGGGTGCCGCTGGTGATGGAAGGCCGCGAGCCGGGGCAGAAGATCGCCGCCACGCGCATGTCGATCGGCACCGACGTCAACTTCGGCGAGATCACTCGCCAACTGGTGGGCTCGCTGTCGGCCAAGGACACCTTCAAGCTGCGCCTGCAACATGAGGTCCGCGACCTCAAGCGCAACGACGACAACACCTGGACCGTGACCATGGCCGACCTGGCCAATGGCGACAAGGAAACCAGCGTCAAGGCCAGGTTCGTCTTCATCGGCGCCGGCGGCGGCGCGCTGAAGCTGCTGCAGATGTCCGGCATCCCCGAGGCCGAAGGCTACGCCGGCTTCCCGGTGGGCGGTTCGTTCCTCGCCACCACCAACCCGGACGTGGTCAAGCGCCACCTGGCCAAGGTCTACGGAAAGGCTTCGGTGGGTTCGCCGCCGATGTCGGTGCCGCACCTCGACACCCGCATGATCGACGGCAAGCCGGTTCTGCTGTTCGGTCCGTTCGCCACTTTCTCCACCAAGTTCCTGAAGAACGGCTCGCTGTGGGACCTGCCGGGCTCGGTGACCAGCGGCAACATCGGCCCGATGTTCAACGCCGGCATCGACAACTTCGATCTCAGCCAGTACCTGATCGGCCAGCTGATGCTCAGCCAGGACGACCGCATGGCCTCGCTGCGCGAGTACTTCCCGGAAGCCCGCGACGAGGACTGGAAGCTGGTGCAGGCCGGCCAGCGCGTGCAGATCATCAAGAAGGACGCCGAGAAAGGCGGCGTACTGCAATTCGGCACCGAAGTGGTGACCGCAGCGGACGGCTCCGTCGCCGCCCTGCTCGGCGCCTCGCCGGGCGCCTCGACCGCCGCGCCGATCATGCTGTCGGTGCTGGAGAAGGCCTTCAAGGACAAGGTCGCTACCCCCGAGTGGCAGGCACGCCTGAAGGAAATCGTGCCGTCTTACGGGCGCAAGCTGAACAACGACATCGAGCTGACCAACAGCACCCGTGCCTGGAGCAGCGAGCGCCTGCAACTGATCCACGTGCCGGTACAGCCGGAGGCCTGA
Protein Properties
Protein Residues: 523
Protein Molecular Weight: 57.2 kDa
Protein Theoretical pI: 5.74
Hydropathicity (GRAVY score): -0.2
Charge at pH 7 (predicted): -6.14
Protein Sequence:
>PA3452
MKKILLMLLCVSVLGCSKNSVESEKPVDVLLIGGGIMSATLGTYLNELEPGWTIEMVERLDKVAEESSNGWNNAGTGHSAFCELNYTSEAADGSMDISKAVAINENFEISKQFWAYQVDRKVLNDPKSFINNVPHMSFVWGDDNVAFLKKRHAALQHSSLFRGMEYSEDPEQIKQWVPLVMEGREPGQKIAATRMSIGTDVNFGEITRQLVGSLSAKDTFKLRLQHEVRDLKRNDDNTWTVTMADLANGDKETSVKARFVFIGAGGGALKLLQMSGIPEAEGYAGFPVGGSFLATTNPDVVKRHLAKVYGKASVGSPPMSVPHLDTRMIDGKPVLLFGPFATFSTKFLKNGSLWDLPGSVTSGNIGPMFNAGIDNFDLSQYLIGQLMLSQDDRMASLREYFPEARDEDWKLVQAGQRVQIIKKDAEKGGVLQFGTEVVTAADGSVAALLGASPGASTAAPIMLSVLEKAFKDKVATPEWQARLKEIVPSYGRKLNNDIELTNSTRAWSSERLQLIHVPVQPEA
References
External Links:
Resource Link
Genome ID: PA3452
Entrez Gene ID: 879029
NCBI Protein ID: 15598648
General Reference: PaperBLAST - Find papers about PA3452 and its homologs