Identification
Name: Histidine transport system permease protein hisM
Synonyms: Not Available
Gene Name: hisM
Enzyme Class: Not Available
Biological Properties
General Function: Involved in transporter activity
Specific Function: Part of the binding-protein-dependent transport system for histidine; probably responsible for the translocation of the substrate across the membrane
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
L-Histidine+Thumb+Thumb+ThumbAdenosine diphosphate+Thumb+Thumb+L-Histidine+Thumb
L-Histidine + Adenosine triphosphate + Water + L-Histidine → Adenosine diphosphate + Phosphate + Hydrogen ion + L-Histidine + ADP
ReactionCard
L-Lysine+Thumb+Thumb+ThumbAdenosine diphosphate+Thumb+Thumb+L-Lysine+Thumb
L-Lysine + Adenosine triphosphate + Water + L-Lysine → Adenosine diphosphate + Phosphate + Hydrogen ion + L-Lysine + ADP
ReactionCard
Thumb
L-histidine[periplasm] + H+[periplasm] → L-histidine[cytosol] + H+[cytosol]
ReactionCard
Complex Reactions: Not Available
Transports:
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000146L-ArginineMetaboCard
PAMDB000074L-HistidineMetaboCard
PAMDB000075L-LysineMetaboCard
PAMDB000087OrnithineMetaboCard
PAMDB000383PhosphateMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Component
cell part
integral to membrane
intrinsic to membrane
membrane
membrane part
Function
transporter activity
Process
establishment of localization
transport
Gene Properties
Locus tag: PA2925
Strand: +
Entrez Gene ID: 882577
Accession: NP_251615.1
GI: 15598121
Sequence start: 3280165
Sequence End: 3280878
Sequence Length: 713
Gene Sequence:
>PA2925
ATGAACGCGGTACTCGACGAATACTGGCAGGCCTACCTGTGGACCGACGGCCTGCAACTGACCGGACTGGCGATGACCCTGTGGCTGCTGATCCTCGCCGTGGCGCTTGGCTTCCTGCTGGCCATCCCGCTGGCGGTGGCGCGGACCTGCGGCAACCCGCTGCTGCGCTACCCGGTCTGGCTCTACACCTACGTGTTCCGCGGCACCCCGCTGTACATCCAGTTGCTGTTCTTCTACACCGGCGTCTACAGCCTGAATGCCATACGCGCCCAGGACTTTCTCAACGCGTTCTTCCGCGACGGCTTCAACTGCACGGTGCTGGCCTTCGTCCTCAACACCTGCGCCTACATGACGGAAATCTTCGCCGGCGCGATCAGGAACACGCCCCACGGCGAAGTGGAAGCGGCGCGCGCCTACGGCATGGGCGGCTTCACCCTCTACCGGCGCATCGTCCTGCCCTCGGCGCTGCGCCGGGCACTGCCGTACTTCAGCAACGAAGTGATCCTGATGCTGCATTCCACCTCGGTGGCGTTCACCGCCACCGTGCCGGACCTGCTCAAGGTGGCCCGCGACGTCAATTCCGCCACCTATGCGCCGTTCCTGTCCTTCGGCATCGCCGGCGCGCTCTACGCCGGCACCGCCTTCCTGCTGATCTGGCTGTTCCGCCGTGGCGAGCTGCGCTGGCTGGCCTACCTCAGACCGCAAACCCACTGA
Protein Properties
Protein Residues: 237
Protein Molecular Weight: 26.7 kDa
Protein Theoretical pI: 9.2
Hydropathicity (GRAVY score): 0.56
Charge at pH 7 (predicted): 5.6
Protein Sequence:
>PA2925
MNAVLDEYWQAYLWTDGLQLTGLAMTLWLLILAVALGFLLAIPLAVARTCGNPLLRYPVWLYTYVFRGTPLYIQLLFFYTGVYSLNAIRAQDFLNAFFRDGFNCTVLAFVLNTCAYMTEIFAGAIRNTPHGEVEAARAYGMGGFTLYRRIVLPSALRRALPYFSNEVILMLHSTSVAFTATVPDLLKVARDVNSATYAPFLSFGIAGALYAGTAFLLIWLFRRGELRWLAYLRPQTH
References
External Links:
Resource Link
Genome ID: PA2925
Entrez Gene ID: 882577
NCBI Protein ID: 15598121
General Reference: PaperBLAST - Find papers about PA2925 and its homologs