Identification
Name: Enoyl-[acyl-carrier-protein] reductase [NADH]
Synonyms:
  • NADH-dependent enoyl-ACP reductase
Gene Name: fabI
Enzyme Class:
Biological Properties
General Function: Involved in enoyl-[acyl-carrier-protein] reductase (NADH) activity
Specific Function: Acyl-[acyl-carrier-protein] + NAD(+) = trans- 2,3-dehydroacyl-[acyl-carrier-protein] + NADH
Cellular Location: Cell inner membrane; Peripheral membrane protein
KEGG Pathways:
KEGG Reactions:
Butyryl-[acp]+ThumbBut-2-enoyl-[acyl-carrier protein]+Thumb+Thumb
Butyryl-[acp] + NAD ↔ But-2-enoyl-[acyl-carrier protein] + NADH + Hydrogen ion
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Dodecanoyl-[acyl-carrier protein]+Thumbtrans-Dodec-2-enoyl-[acp]+Thumb+Thumb
Dodecanoyl-[acyl-carrier protein] + NAD ↔ trans-Dodec-2-enoyl-[acp] + NADH + Hydrogen ion
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Hexanoyl-[acp]+Thumbtrans-Hex-2-enoyl-[acp]+Thumb+Thumb
Hexanoyl-[acp] + NAD ↔ trans-Hex-2-enoyl-[acp] + NADH + Hydrogen ion
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Octanoyl-[acp]+Thumbtrans-Oct-2-enoyl-[acp]+Thumb+Thumb
Octanoyl-[acp] + NAD ↔ trans-Oct-2-enoyl-[acp] + NADH + Hydrogen ion
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Decanoyl-[acp]+Thumbtrans-Dec-2-enoyl-[acp]+Thumb+Thumb
Decanoyl-[acp] + NAD ↔ trans-Dec-2-enoyl-[acp] + NADH + Hydrogen ion
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Tetradecanoyl-[acp]+Thumbtrans-Tetradec-2-enoyl-[acp]+Thumb+Thumb
Tetradecanoyl-[acp] + NAD ↔ trans-Tetradec-2-enoyl-[acp] + NADH + Hydrogen ion
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Hexadecanoyl-[acp]+Thumbtrans-Hexadec-2-enoyl-[acp]+Thumb+Thumb
Hexadecanoyl-[acp] + NAD ↔ trans-Hexadec-2-enoyl-[acp] + NADH + Hydrogen ion
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(2E)-Octadecenoyl-[acp]+Thumb+ThumbOctadecanoyl-[acyl-carrier protein]+Thumb
(2E)-Octadecenoyl-[acp] + NADH + Hydrogen ion ↔ Octadecanoyl-[acyl-carrier protein] + NAD
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Acyl-[acyl-carrier protein]+Thumbtrans-2,3-Dehydroacyl-[acyl-carrier protein]+Thumb+Thumb
Acyl-[acyl-carrier protein] + NAD ↔ trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + Hydrogen ion
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SMPDB Reactions:
Glutaryl-[acp] methyl ester +ThumbNADPH+Thumb+Enoylglutaryl-[acp] methyl ester +Thumb
Glutaryl-[acp] methyl ester + NADP ← NADPH + Hydrogen ion + Enoylglutaryl-[acp] methyl ester + NADPH
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NADPH+Thumb+an enoylpimeloyl-[acp] methyl ester+ThumbThumb+a pimeloyl-[acp] methyl ester
NADPH + Hydrogen ion + an enoylpimeloyl-[acp] methyl ester + NADPHNADP + a pimeloyl-[acp] methyl ester
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trans-2-enoyl-[acyl-carrier protein]+Thumb+NADPH+ThumbThumb+2,3,4-saturated fatty acyl-[acp]
trans-2-enoyl-[acyl-carrier protein] + Hydrogen ion + NADPH + NADPHNADP + 2,3,4-saturated fatty acyl-[acp]
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trans-?3-cis-?5-dodecenoyl-[acp]+Thumb+Thumbcis-?5-dodecenoyl-[acp]?+Thumb
trans-?3-cis-?5-dodecenoyl-[acp] + Hydrogen ion + NADH → cis-?5-dodecenoyl-[acp]? + NAD
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trans-?3-cis-?7-tetradecenoyl-[acp]+Thumb+ThumbThumb+cis-?7-tetradecenoyl-[acp]?
trans-?3-cis-?7-tetradecenoyl-[acp] + Hydrogen ion + NADHNAD + cis-?7-tetradecenoyl-[acp]?
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trans-?3-cis-?9-hexadecenoyl-[acp]+Thumb+ThumbThumb+a palmitoleoyl-[acp]?
trans-?3-cis-?9-hexadecenoyl-[acp] + Hydrogen ion + NADHNAD + a palmitoleoyl-[acp]?
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cis-vaccen-2-enoyl-[acp] +Thumb+ThumbThumb+ a cis-vaccenoyl-[acp]
cis-vaccen-2-enoyl-[acp] + Hydrogen ion + NADHNAD + a cis-vaccenoyl-[acp]
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trans-2-enoyl-[acyl-carrier protein]+Thumb+ThumbThumb+2,3,4-saturated fatty acyl-[acp]
trans-2-enoyl-[acyl-carrier protein] + Hydrogen ion + NADHNAD + 2,3,4-saturated fatty acyl-[acp]
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crotonyl-[acp] +Thumb+ThumbThumb+butyryl-[acp]
crotonyl-[acp] + Hydrogen ion + NADHNAD + butyryl-[acp]
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trans hex-2-enoyl-[acp]+Thumb+ThumbThumb+hexanoyl-[acyl-carrier-protein]
trans hex-2-enoyl-[acp] + Hydrogen ion + NADHNAD + hexanoyl-[acyl-carrier-protein]
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trans oct-2-enoyl-[acp] +Thumb+ThumbThumb+Octanoyl-[acyl-carrier protein]
trans oct-2-enoyl-[acp] + Hydrogen ion + NADHNAD + Octanoyl-[acyl-carrier protein]
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a trans-?2-decenoyl-[acp]?+Thumb+ThumbThumb+decanoyl-[acp]
a trans-?2-decenoyl-[acp]? + Hydrogen ion + NADHNAD + decanoyl-[acp]
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trans dodec-2-enoyl-[acp]+Thumb+ThumbThumb+dodecanoyl-[acp]?
trans dodec-2-enoyl-[acp] + Hydrogen ion + NADHNAD + dodecanoyl-[acp]?
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trans tetradec-2-enoyl-[acp]+Thumb+ThumbThumb+ myristoyl-[acp]
trans tetradec-2-enoyl-[acp] + Hydrogen ion + NADHNAD + myristoyl-[acp]
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Thumb+Thumb+ trans hexadecenoyl-[acp]Thumb+palmitoyl-[acp]
Hydrogen ion + NADH + trans hexadecenoyl-[acp] → NAD + palmitoyl-[acp]
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PseudoCyc/BioCyc Reactions:
But-2-enoyl-[acyl-carrier protein]+Thumb+ThumbButyryl-ACP (n-C4:0ACP)+Thumb
But-2-enoyl-[acyl-carrier protein] + Hydrogen ion + NADH → Butyryl-ACP (n-C4:0ACP) + NAD
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But-2-enoyl-[acyl-carrier protein]+Thumb+ThumbButyryl-ACP (n-C4:0ACP)+Thumb
But-2-enoyl-[acyl-carrier protein] + Hydrogen ion + NADPH → Butyryl-ACP (n-C4:0ACP) + NADP
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Thumb+Thumb+trans-3-cis-11-vacceoyl-[acyl-carrier protein]Thumb+cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)
Hydrogen ion + NADH + trans-3-cis-11-vacceoyl-[acyl-carrier protein] → NAD + cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)
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Thumb+Thumb+trans-3-cis-5-dodecenoyl-[acyl-carrier protein]cis-dodec-5-enoyl-[acyl-carrier protein] (n-C12:1)+Thumb
Hydrogen ion + NADH + trans-3-cis-5-dodecenoyl-[acyl-carrier protein] → cis-dodec-5-enoyl-[acyl-carrier protein] (n-C12:1) + NAD
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Thumb+Thumb+trans-3-cis-7-myristoleoyl-[acyl-carrier protein]Thumb+cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
Hydrogen ion + NADH + trans-3-cis-7-myristoleoyl-[acyl-carrier protein] → NAD + cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
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Thumb+Thumb+trans-3-cis-9-palmitoleoyl-[acyl-carrier protein]cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)+Thumb
Hydrogen ion + NADH + trans-3-cis-9-palmitoleoyl-[acyl-carrier protein] → cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1) + NAD
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Thumb+Thumb+trans-Dec-2-enoyl-[acyl-carrier protein]Decanoyl-ACP (n-C10:0ACP)+Thumb
Hydrogen ion + NADH + trans-Dec-2-enoyl-[acyl-carrier protein] → Decanoyl-ACP (n-C10:0ACP) + NAD
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Thumb+Thumb+trans-Dodec-2-enoyl-[acyl-carrier protein]Dodecanoyl-ACP (n-C12:0ACP)+Thumb
Hydrogen ion + NADH + trans-Dodec-2-enoyl-[acyl-carrier protein] → Dodecanoyl-ACP (n-C12:0ACP) + NAD
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Thumb+Thumb+trans-Hex-2-enoyl-[acyl-carrier protein]Hexanoyl-ACP (n-C6:0ACP)+Thumb
Hydrogen ion + NADH + trans-Hex-2-enoyl-[acyl-carrier protein] → Hexanoyl-ACP (n-C6:0ACP) + NAD
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Thumb+Thumb+trans-Hexadec-2-enoyl-[acyl-carrier protein]Thumb+Palmitoyl-ACP (n-C16:0ACP)
Hydrogen ion + NADH + trans-Hexadec-2-enoyl-[acyl-carrier protein] → NAD + Palmitoyl-ACP (n-C16:0ACP)
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Thumb+Thumb+trans-Oct-2-enoyl-[acyl-carrier protein]Thumb+Octanoyl-ACP (n-C8:0ACP)
Hydrogen ion + NADH + trans-Oct-2-enoyl-[acyl-carrier protein] → NAD + Octanoyl-ACP (n-C8:0ACP)
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Thumb+Thumb+trans-octadec-2-enoyl-[acyl-carrier protein]Thumb+Octadecanoyl-ACP (n-C18:0ACP)
Hydrogen ion + NADH + trans-octadec-2-enoyl-[acyl-carrier protein] → NAD + Octadecanoyl-ACP (n-C18:0ACP)
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Thumb+Thumb+trans-Tetradec-2-enoyl-[acyl-carrier protein]Myristoyl-ACP (n-C14:0ACP)+Thumb
Hydrogen ion + NADH + trans-Tetradec-2-enoyl-[acyl-carrier protein] → Myristoyl-ACP (n-C14:0ACP) + NAD
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Thumb+Thumb+trans-3-cis-11-vacceoyl-[acyl-carrier protein]Thumb+cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)
Hydrogen ion + NADPH + trans-3-cis-11-vacceoyl-[acyl-carrier protein] → NADP + cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)
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Thumb+Thumb+trans-3-cis-5-dodecenoyl-[acyl-carrier protein]cis-dodec-5-enoyl-[acyl-carrier protein] (n-C12:1)+Thumb
Hydrogen ion + NADPH + trans-3-cis-5-dodecenoyl-[acyl-carrier protein] → cis-dodec-5-enoyl-[acyl-carrier protein] (n-C12:1) + NADP
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Thumb+Thumb+trans-3-cis-7-myristoleoyl-[acyl-carrier protein]Thumb+cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
Hydrogen ion + NADPH + trans-3-cis-7-myristoleoyl-[acyl-carrier protein] → NADP + cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
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Thumb+Thumb+trans-3-cis-9-palmitoleoyl-[acyl-carrier protein]cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)+Thumb
Hydrogen ion + NADPH + trans-3-cis-9-palmitoleoyl-[acyl-carrier protein] → cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1) + NADP
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Thumb+Thumb+trans-Dec-2-enoyl-[acyl-carrier protein]Decanoyl-ACP (n-C10:0ACP)+Thumb
Hydrogen ion + NADPH + trans-Dec-2-enoyl-[acyl-carrier protein] → Decanoyl-ACP (n-C10:0ACP) + NADP
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Thumb+Thumb+trans-Dodec-2-enoyl-[acyl-carrier protein]Dodecanoyl-ACP (n-C12:0ACP)+Thumb
Hydrogen ion + NADPH + trans-Dodec-2-enoyl-[acyl-carrier protein] → Dodecanoyl-ACP (n-C12:0ACP) + NADP
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Thumb+Thumb+trans-Hex-2-enoyl-[acyl-carrier protein]Hexanoyl-ACP (n-C6:0ACP)+Thumb
Hydrogen ion + NADPH + trans-Hex-2-enoyl-[acyl-carrier protein] → Hexanoyl-ACP (n-C6:0ACP) + NADP
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Thumb+Thumb+trans-Hexadec-2-enoyl-[acyl-carrier protein]Thumb+Palmitoyl-ACP (n-C16:0ACP)
Hydrogen ion + NADPH + trans-Hexadec-2-enoyl-[acyl-carrier protein] → NADP + Palmitoyl-ACP (n-C16:0ACP)
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Thumb+Thumb+trans-Oct-2-enoyl-[acyl-carrier protein]Thumb+Octanoyl-ACP (n-C8:0ACP)
Hydrogen ion + NADPH + trans-Oct-2-enoyl-[acyl-carrier protein] → NADP + Octanoyl-ACP (n-C8:0ACP)
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Thumb+Thumb+trans-octadec-2-enoyl-[acyl-carrier protein]Thumb+Octadecanoyl-ACP (n-C18:0ACP)
Hydrogen ion + NADPH + trans-octadec-2-enoyl-[acyl-carrier protein] → NADP + Octadecanoyl-ACP (n-C18:0ACP)
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Thumb+Thumb+trans-Tetradec-2-enoyl-[acyl-carrier protein]Myristoyl-ACP (n-C14:0ACP)+Thumb
Hydrogen ion + NADPH + trans-Tetradec-2-enoyl-[acyl-carrier protein] → Myristoyl-ACP (n-C14:0ACP) + NADP
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Enoylglutaryl-[acyl-carrier protein] methyl ester+Thumb+ThumbGlutaryl-[acyl-carrier protein] methyl ester+Thumb
Enoylglutaryl-[acyl-carrier protein] methyl ester + Hydrogen ion + NADPH → Glutaryl-[acyl-carrier protein] methyl ester + NADP
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Enoylpimeloyl-[acyl-carrier protein] methyl ester+Thumb+ThumbThumb+Pimeloyl-[acyl-carrier protein] methyl ester
Enoylpimeloyl-[acyl-carrier protein] methyl ester + Hydrogen ion + NADPHNADP + Pimeloyl-[acyl-carrier protein] methyl ester
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Hexanoyl-[acp]+Thumbtrans-Hex-2-enoyl-[acp]+Thumb+Thumb
Hexanoyl-[acp] + NAD ↔ trans-Hex-2-enoyl-[acp] + NADH + Hydrogen ion
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Octanoyl-[acp]+Thumbtrans-Oct-2-enoyl-[acp]+Thumb+Thumb
Octanoyl-[acp] + NAD ↔ trans-Oct-2-enoyl-[acp] + NADH + Hydrogen ion
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Decanoyl-[acp]+Thumbtrans-Dec-2-enoyl-[acp]+Thumb+Thumb
Decanoyl-[acp] + NAD ↔ trans-Dec-2-enoyl-[acp] + NADH + Hydrogen ion
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Tetradecanoyl-[acp]+Thumbtrans-Tetradec-2-enoyl-[acp]+Thumb+Thumb
Tetradecanoyl-[acp] + NAD ↔ trans-Tetradec-2-enoyl-[acp] + NADH + Hydrogen ion
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Hexadecanoyl-[acp]+Thumbtrans-Hexadec-2-enoyl-[acp]+Thumb+Thumb
Hexadecanoyl-[acp] + NAD ↔ trans-Hexadec-2-enoyl-[acp] + NADH + Hydrogen ion
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Butyryl-[acp]+ThumbBut-2-enoyl-[acyl-carrier protein]+Thumb+Thumb
Butyryl-[acp] + NAD ↔ But-2-enoyl-[acyl-carrier protein] + NADH + Hydrogen ion
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Dodecanoyl-[acyl-carrier protein]+Thumbtrans-Dodec-2-enoyl-[acp]+Thumb+Thumb
Dodecanoyl-[acyl-carrier protein] + NAD ↔ trans-Dodec-2-enoyl-[acp] + NADH + Hydrogen ion
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(2E)-Octadecenoyl-[acp]+Thumb+ThumbOctadecanoyl-[acyl-carrier protein]+Thumb
(2E)-Octadecenoyl-[acp] + NADH + Hydrogen ion ↔ Octadecanoyl-[acyl-carrier protein] + NAD
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Acyl-[acyl-carrier-protein]+Thumbtrans-2,3-dehydroacyl-[acyl-carrier-protein]+Thumb
Acyl-[acyl-carrier-protein] + NAD → trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH
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Acyl-[acyl-carrier protein]+Thumbtrans-2,3-Dehydroacyl-[acyl-carrier protein]+Thumb+Thumb
Acyl-[acyl-carrier protein] + NAD ↔ trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + Hydrogen ion
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Glutaryl-[acp] methyl ester +ThumbNADPH+Thumb+Enoylglutaryl-[acp] methyl ester +Thumb
Glutaryl-[acp] methyl ester + NADP ← NADPH + Hydrogen ion + Enoylglutaryl-[acp] methyl ester + NADPH
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NADPH+Thumb+an enoylpimeloyl-[acp] methyl ester+ThumbThumb+a pimeloyl-[acp] methyl ester
NADPH + Hydrogen ion + an enoylpimeloyl-[acp] methyl ester + NADPHNADP + a pimeloyl-[acp] methyl ester
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trans-2-enoyl-[acyl-carrier protein]+Thumb+NADPH+ThumbThumb+2,3,4-saturated fatty acyl-[acp]
trans-2-enoyl-[acyl-carrier protein] + Hydrogen ion + NADPH + NADPHNADP + 2,3,4-saturated fatty acyl-[acp]
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trans-?3-cis-?5-dodecenoyl-[acp]+Thumb+Thumbcis-?5-dodecenoyl-[acp]?+Thumb
trans-?3-cis-?5-dodecenoyl-[acp] + Hydrogen ion + NADH → cis-?5-dodecenoyl-[acp]? + NAD
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trans-?3-cis-?7-tetradecenoyl-[acp]+Thumb+ThumbThumb+cis-?7-tetradecenoyl-[acp]?
trans-?3-cis-?7-tetradecenoyl-[acp] + Hydrogen ion + NADHNAD + cis-?7-tetradecenoyl-[acp]?
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trans-?3-cis-?9-hexadecenoyl-[acp]+Thumb+ThumbThumb+a palmitoleoyl-[acp]?
trans-?3-cis-?9-hexadecenoyl-[acp] + Hydrogen ion + NADHNAD + a palmitoleoyl-[acp]?
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cis-vaccen-2-enoyl-[acp] +Thumb+ThumbThumb+ a cis-vaccenoyl-[acp]
cis-vaccen-2-enoyl-[acp] + Hydrogen ion + NADHNAD + a cis-vaccenoyl-[acp]
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trans-2-enoyl-[acyl-carrier protein]+Thumb+ThumbThumb+2,3,4-saturated fatty acyl-[acp]
trans-2-enoyl-[acyl-carrier protein] + Hydrogen ion + NADHNAD + 2,3,4-saturated fatty acyl-[acp]
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crotonyl-[acp] +Thumb+ThumbThumb+butyryl-[acp]
crotonyl-[acp] + Hydrogen ion + NADHNAD + butyryl-[acp]
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trans hex-2-enoyl-[acp]+Thumb+ThumbThumb+hexanoyl-[acyl-carrier-protein]
trans hex-2-enoyl-[acp] + Hydrogen ion + NADHNAD + hexanoyl-[acyl-carrier-protein]
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trans oct-2-enoyl-[acp] +Thumb+ThumbThumb+Octanoyl-[acyl-carrier protein]
trans oct-2-enoyl-[acp] + Hydrogen ion + NADHNAD + Octanoyl-[acyl-carrier protein]
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a trans-?2-decenoyl-[acp]?+Thumb+ThumbThumb+decanoyl-[acp]
a trans-?2-decenoyl-[acp]? + Hydrogen ion + NADHNAD + decanoyl-[acp]
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trans dodec-2-enoyl-[acp]+Thumb+ThumbThumb+dodecanoyl-[acp]?
trans dodec-2-enoyl-[acp] + Hydrogen ion + NADHNAD + dodecanoyl-[acp]?
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trans tetradec-2-enoyl-[acp]+Thumb+ThumbThumb+ myristoyl-[acp]
trans tetradec-2-enoyl-[acp] + Hydrogen ion + NADHNAD + myristoyl-[acp]
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Thumb+Thumb+ trans hexadecenoyl-[acp]Thumb+palmitoyl-[acp]
Hydrogen ion + NADH + trans hexadecenoyl-[acp] → NAD + palmitoyl-[acp]
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Thumb
a 2,3,4-saturated fatty acyl-[acp] + NAD+ ← a trans-2-enoyl-[acyl-carrier protein] + NADH + H+
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PAMDB110542PAMDB110540+PAMDB001633
Complex Reactions:
But-2-enoyl-[acyl-carrier protein]+Thumb+ThumbButyryl-ACP (n-C4:0ACP)+Thumb
But-2-enoyl-[acyl-carrier protein] + Hydrogen ion + NADH → Butyryl-ACP (n-C4:0ACP) + NAD
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But-2-enoyl-[acyl-carrier protein]+Thumb+ThumbButyryl-ACP (n-C4:0ACP)+Thumb
But-2-enoyl-[acyl-carrier protein] + Hydrogen ion + NADPH → Butyryl-ACP (n-C4:0ACP) + NADP
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Thumb+Thumb+trans-3-cis-11-vacceoyl-[acyl-carrier protein]Thumb+cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)
Hydrogen ion + NADH + trans-3-cis-11-vacceoyl-[acyl-carrier protein] → NAD + cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)
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Thumb+Thumb+trans-3-cis-5-dodecenoyl-[acyl-carrier protein]cis-dodec-5-enoyl-[acyl-carrier protein] (n-C12:1)+Thumb
Hydrogen ion + NADH + trans-3-cis-5-dodecenoyl-[acyl-carrier protein] → cis-dodec-5-enoyl-[acyl-carrier protein] (n-C12:1) + NAD
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Thumb+Thumb+trans-3-cis-7-myristoleoyl-[acyl-carrier protein]Thumb+cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
Hydrogen ion + NADH + trans-3-cis-7-myristoleoyl-[acyl-carrier protein] → NAD + cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
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Thumb+Thumb+trans-3-cis-9-palmitoleoyl-[acyl-carrier protein]cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)+Thumb
Hydrogen ion + NADH + trans-3-cis-9-palmitoleoyl-[acyl-carrier protein] → cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1) + NAD
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Thumb+Thumb+trans-Dec-2-enoyl-[acyl-carrier protein]Decanoyl-ACP (n-C10:0ACP)+Thumb
Hydrogen ion + NADH + trans-Dec-2-enoyl-[acyl-carrier protein] → Decanoyl-ACP (n-C10:0ACP) + NAD
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Thumb+Thumb+trans-Dodec-2-enoyl-[acyl-carrier protein]Dodecanoyl-ACP (n-C12:0ACP)+Thumb
Hydrogen ion + NADH + trans-Dodec-2-enoyl-[acyl-carrier protein] → Dodecanoyl-ACP (n-C12:0ACP) + NAD
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Thumb+Thumb+trans-Hex-2-enoyl-[acyl-carrier protein]Hexanoyl-ACP (n-C6:0ACP)+Thumb
Hydrogen ion + NADH + trans-Hex-2-enoyl-[acyl-carrier protein] → Hexanoyl-ACP (n-C6:0ACP) + NAD
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Thumb+Thumb+trans-Hexadec-2-enoyl-[acyl-carrier protein]Thumb+Palmitoyl-ACP (n-C16:0ACP)
Hydrogen ion + NADH + trans-Hexadec-2-enoyl-[acyl-carrier protein] → NAD + Palmitoyl-ACP (n-C16:0ACP)
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Thumb+Thumb+trans-Oct-2-enoyl-[acyl-carrier protein]Thumb+Octanoyl-ACP (n-C8:0ACP)
Hydrogen ion + NADH + trans-Oct-2-enoyl-[acyl-carrier protein] → NAD + Octanoyl-ACP (n-C8:0ACP)
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Thumb+Thumb+trans-octadec-2-enoyl-[acyl-carrier protein]Thumb+Octadecanoyl-ACP (n-C18:0ACP)
Hydrogen ion + NADH + trans-octadec-2-enoyl-[acyl-carrier protein] → NAD + Octadecanoyl-ACP (n-C18:0ACP)
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Thumb+Thumb+trans-Tetradec-2-enoyl-[acyl-carrier protein]Myristoyl-ACP (n-C14:0ACP)+Thumb
Hydrogen ion + NADH + trans-Tetradec-2-enoyl-[acyl-carrier protein] → Myristoyl-ACP (n-C14:0ACP) + NAD
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Thumb+Thumb+trans-3-cis-11-vacceoyl-[acyl-carrier protein]Thumb+cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)
Hydrogen ion + NADPH + trans-3-cis-11-vacceoyl-[acyl-carrier protein] → NADP + cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)
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Thumb+Thumb+trans-3-cis-5-dodecenoyl-[acyl-carrier protein]cis-dodec-5-enoyl-[acyl-carrier protein] (n-C12:1)+Thumb
Hydrogen ion + NADPH + trans-3-cis-5-dodecenoyl-[acyl-carrier protein] → cis-dodec-5-enoyl-[acyl-carrier protein] (n-C12:1) + NADP
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Thumb+Thumb+trans-3-cis-7-myristoleoyl-[acyl-carrier protein]Thumb+cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
Hydrogen ion + NADPH + trans-3-cis-7-myristoleoyl-[acyl-carrier protein] → NADP + cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
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Thumb+Thumb+trans-3-cis-9-palmitoleoyl-[acyl-carrier protein]cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)+Thumb
Hydrogen ion + NADPH + trans-3-cis-9-palmitoleoyl-[acyl-carrier protein] → cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1) + NADP
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Thumb+Thumb+trans-Dec-2-enoyl-[acyl-carrier protein]Decanoyl-ACP (n-C10:0ACP)+Thumb
Hydrogen ion + NADPH + trans-Dec-2-enoyl-[acyl-carrier protein] → Decanoyl-ACP (n-C10:0ACP) + NADP
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Thumb+Thumb+trans-Dodec-2-enoyl-[acyl-carrier protein]Dodecanoyl-ACP (n-C12:0ACP)+Thumb
Hydrogen ion + NADPH + trans-Dodec-2-enoyl-[acyl-carrier protein] → Dodecanoyl-ACP (n-C12:0ACP) + NADP
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Thumb+Thumb+trans-Hex-2-enoyl-[acyl-carrier protein]Hexanoyl-ACP (n-C6:0ACP)+Thumb
Hydrogen ion + NADPH + trans-Hex-2-enoyl-[acyl-carrier protein] → Hexanoyl-ACP (n-C6:0ACP) + NADP
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Thumb+Thumb+trans-Hexadec-2-enoyl-[acyl-carrier protein]Thumb+Palmitoyl-ACP (n-C16:0ACP)
Hydrogen ion + NADPH + trans-Hexadec-2-enoyl-[acyl-carrier protein] → NADP + Palmitoyl-ACP (n-C16:0ACP)
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Thumb+Thumb+trans-Oct-2-enoyl-[acyl-carrier protein]Thumb+Octanoyl-ACP (n-C8:0ACP)
Hydrogen ion + NADPH + trans-Oct-2-enoyl-[acyl-carrier protein] → NADP + Octanoyl-ACP (n-C8:0ACP)
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Thumb+Thumb+trans-octadec-2-enoyl-[acyl-carrier protein]Thumb+Octadecanoyl-ACP (n-C18:0ACP)
Hydrogen ion + NADPH + trans-octadec-2-enoyl-[acyl-carrier protein] → NADP + Octadecanoyl-ACP (n-C18:0ACP)
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Thumb+Thumb+trans-Tetradec-2-enoyl-[acyl-carrier protein]Myristoyl-ACP (n-C14:0ACP)+Thumb
Hydrogen ion + NADPH + trans-Tetradec-2-enoyl-[acyl-carrier protein] → Myristoyl-ACP (n-C14:0ACP) + NADP
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Enoylglutaryl-[acyl-carrier protein] methyl ester+Thumb+ThumbGlutaryl-[acyl-carrier protein] methyl ester+Thumb
Enoylglutaryl-[acyl-carrier protein] methyl ester + Hydrogen ion + NADPH → Glutaryl-[acyl-carrier protein] methyl ester + NADP
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Enoylpimeloyl-[acyl-carrier protein] methyl ester+Thumb+ThumbThumb+Pimeloyl-[acyl-carrier protein] methyl ester
Enoylpimeloyl-[acyl-carrier protein] methyl ester + Hydrogen ion + NADPHNADP + Pimeloyl-[acyl-carrier protein] methyl ester
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Acyl-[acyl-carrier-protein]+Thumbtrans-2,3-dehydroacyl-[acyl-carrier-protein]+Thumb
Acyl-[acyl-carrier-protein] + NAD → trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH
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Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB001633Hydrogen ionMetaboCard
PAMDB000197NADMetaboCard
PAMDB000398NADHMetaboCard
PAMDB000089NADPMetaboCard
PAMDB000615NADPHMetaboCard
GO Classification:
Function
acyltransferase activity
binding
catalytic activity
enoyl-[acyl-carrier-protein] reductase (NADH) activity
fatty acid synthase activity
oxidoreductase activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
Process
carboxylic acid metabolic process
cellular metabolic process
fatty acid biosynthetic process
fatty acid metabolic process
metabolic process
monocarboxylic acid metabolic process
organic acid metabolic process
oxidation reduction
oxoacid metabolic process
Gene Properties
Locus tag: PA1806
Strand: -
Entrez Gene ID: 878311
Accession: NP_250497.1
GI: 15597003
Sequence start: 1961227
Sequence End: 1962024
Sequence Length: 797
Gene Sequence:
>PA1806
ATGGGATTTCTCACAGGAAAACGCGCCCTGATCGTCGGAGTCGCCAGCAAGCTCTCCATCGCTTCCGGCATCGCCGCCGCCATGCACCGGGAAGGCGCCGAACTGGCCTTCACCTACCAGAACGACAAGCTCAGGGGCCGGGTGGAGGAGTTCGCCAGTGGCTGGGGCTCGCGGCCGGAGCTGTGCTTCCCCTGTGACGTGGCCGACGACAGCCAGATCGAAGCGGTGTTCGCCGCCCTGGGCAAGCACTGGGACGGCCTGGACATCATCGTCCACTCCGTCGGATTCGCTCCAGGCGATCAGCTCGACGGCGACTTCACCGCGGTGACCACCCGCGAGGGCTTCCGCATCGCCCACGACATCAGCGCCTACAGCTTCATCGCCCTGGCCAAGGCCGGACGGGAAATGATGAAGGGCCGCAACGGCAGCCTGCTGACCCTCTCCTACCTGGGCGCCGAACGGACCATGCCGAACTACAACGTAATGGGCATGGCCAAGGCCAGCCTGGAGGCCGGGGTCCGCTACCTGGCCGGCAGCCTGGGCGCGGAAGGCACCCGGGTCAATGCGGTTTCCGCCGGGCCGATCCGAACGCTCGCCGCCTCCGGGATCAAGAGTTTCCGCAAAATGCTGGCCGCCAACGAGCGGCAGACGCCGCTGCGGCGCAACGTCACCATCGAGGAAGTCGGCAATGCCGGCGCCTTCCTCTGTTCGGACCTGGCCAGCGGTATCAGTGGCGAGATCCTCTACGTCGATGGCGGCTTCAACACTACCGCCATGGGCCCGCTGGACGACGACTGA
Protein Properties
Protein Residues: 265
Protein Molecular Weight: 28 kDa
Protein Theoretical pI: 5.72
Hydropathicity (GRAVY score): 0.028
Charge at pH 7 (predicted): -3.13
Protein Sequence:
>PA1806
MGFLTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPELCFPCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAHDISAYSFIALAKAGREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLAGSLGAEGTRVNAVSAGPIRTLAASGIKSFRKMLAANERQTPLRRNVTIEEVGNAGAFLCSDLASGISGEILYVDGGFNTTAMGPLDDD
References
External Links:
Resource Link
Genome ID: PA1806
Entrez Gene ID: 878311
NCBI Protein ID: 15597003
General Reference: PaperBLAST - Find papers about PA1806 and its homologs