Identification
Name: GTP pyrophosphokinase
Synonyms:
  • (p)ppGpp synthase
  • ATP:GTP 3'-pyrophosphotransferase
  • ppGpp synthase I
Gene Name: relA
Enzyme Class:
Biological Properties
General Function: Involved in amino acid binding
Specific Function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+ThumbThumb+Thumb+Thumb
Thumb+ThumbThumb+Thumb
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+ThumbThumb+Thumb+Thumb
Thumb+ThumbThumb+Thumb+Thumb
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
Complex Reactions:
Thumb+ThumbThumb+Thumb
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000014Adenosine monophosphateMetaboCard
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB001005Guanosine 3',5'-bis(diphosphate)MetaboCard
PAMDB001003Guanosine 3'-diphosphate 5'-triphosphateMetaboCard
PAMDB000296Guanosine diphosphateMetaboCard
PAMDB000319Guanosine triphosphateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
GO Classification:
Function
amino acid binding
binding
carboxylic acid binding
Process
cellular nitrogen compound metabolic process
guanosine metabolic process
guanosine tetraphosphate metabolic process
metabolic process
nitrogen compound metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleoside metabolic process
purine ribonucleoside metabolic process
ribonucleoside metabolic process
Gene Properties
Locus tag: PA0934
Strand: +
Entrez Gene ID: 881299
Accession: NP_249625.1
GI: 15596131
Sequence start: 1023053
Sequence End: 1025296
Sequence Length: 2243
Gene Sequence:
>PA0934
ATGGTACAGGTGAGAGCGCACCAGCCGGTCAACACCGACGGCAGTATCAACCTCGAGGCCTGGCTGGACCACGTCCAGAACCTCGTCCCCGGGCTCGATCGTCAGGGCTTGCTGGAGGCTTGCGAGTTCGCTCGCGAATCCGAGCAGCGAGCGATCGCCGCACAGAACTCCTGGGCGGAAGGCACGTCCAGCTTCCAGACCGGACTGGAAATCGCCGAGATCCTCGCGGATCTCAAGCTGGATCAGGAGTCCCTGGTCGCCGCGGTCATCTATCGAGGCGTGCGGGAAGGCAAGATCACCCTGGAAGCGGTCAACAAGCATTTCGGGCCGGTGGTGGCCAAGCTGATCGAGGGCGTGCTGCGCATGGCCGCGATCAGCGCCAGCCTCAATCCGCGCCATTCCATGGTGCTGGGTACCCAGGCGCAGGTGGAGAACCTGCGCAAGATGCTGGTGGCGATGGTCGACGACGTTCGCGTCGCCCTGATCAAGCTGGCCGAGCGCACCTGCGCCATTCGCGCGGTGAAGAACGCCGACGAGGAAAAGCGCCACCGCGTCGCCCGGGAAGTCTTCGATATCTACGCGCCGCTGGCCCACCGCCTGGGCATCGGGCATATCAAGTGGGAGCTGGAGGACCTGTCCTTCCGTTACCTCGAGCCCGACCAGTACAAGCAGATCGCCAAGCTGCTGCACGAGCGCCGGCTGGATCGTGAGCAGTACATCGCCAACGTGATGAGCCAGTTGAAGGAAGCTCTCGCGGCCACCGGCGTACAGGCCGATCTCAGCGGACGGGCGAAACACATCTATTCGATCTGGCGCAAGATGCAGCGCAAGGGCCTGGACTTCAGCCAGATCTACGACGTTCGCGCCGTGCGCGTGCTCGTTCCGGAGATGCGCGACTGCTACACCGCGCTGGGCATCGTGCATACCCTCTGGCGGCACATTCCCAAGGAGTTCGACGACTACATCGCCAACCCCAAGGAAAACGGCTATCGCTCGCTGCATACCGCAGTGATCGGCCCCGAGGGGAAGGTGCTGGAAGTACAGATCCGTACCCACTCCATGCACGAAGAGGCGGAGCTCGGAGTCTGCGCGCACTGGCGCTACAAGGGGACCGACGTCAAGGCCAGCTCCAACCATTACGAGGAAAAGATCTCCTGGCTGCGCCAGGTGCTCGAATGGCACGAGGAACTGGGCGACATCGGTGGCCTGGCGGAGCAACTGCGGGTCGATATCGAGCCGGACAGGGTCTACGTCTTCACTCCCGACGGCCATGCCATCGACCTGCCCAAGGGCGCGACCCCGCTGGATTTCGCCTATCGGGTCCACACTGAAGTCGGGCACAACTGCCGCGGGGCGAAGATCAACGGACGCATCGTGCCGCTGAACTACAGCCTGCAGACCGGCGAGCAGGTCGAGATCATAACCGGCAAGCACAGCGGTCCGAGCCGCGACTGGCTGAACAGCAACCTGGGCTACGTCACCACCTCCCGGGCGCGGGCGAAGATCGTCCACTGGTTCAAGCTGCAGGCGCGGGACCAGAACGTCGCTGCCGGCAAGGCCCTGATCGAACGCGAGCTGTCGCGCCTGGCGCTGCCGCCGGTGGATTTCGACCGGCTGGCGGAGAAGGCCAACGTGCGTACCGCCGAGGATATGTTCGCCGCTCTCGGCGCCGGCGACCTGCGCTTGGCGCACCTGGTCAACTATGCCCAGCAACTGGTCGAGCCGGACCGCGACAGCGAGCAACTCGAACTGATCCCGCGCAAGCCGAGCAAGATCGGCCACGGCAAGCGCGGCGACGTGCAGATCCAGGGTGTCGGCAACCTCCTGACGCAGATGGCCGGCTGCTGCCAGCCGCTGCCGGGAGATCCCATCGTCGGCTACATCACGCTGGGCCGTGGGGTCACCATCCACCGCCAGGATTGCGCCACCGCGCTGCAACTGGCGGGACGCGAACCGGAGCGGATGATCCAGGTCAGCTGGGGGCCGGAGCCGGTTCGCACCTATCCGGTGGATATCGCGATCCGTGCCTATGATCGTTCCGGCCTGTTGCGCGACGTGTCCCAGGTGCTGCTCAACGAGCGGATCAACGTTCTGGCGGTGAATACCCGTTCGAACAAGGAAGACAACACCGCGACCATGCAACTGACCATCGAGATTCCCGGTCTGGACGCTCTTGGACGCCTGCTGGCGCGCGTCTCGCAACTGCCCAACATCATCGAGGCGCGGCGCAACCGTACGCCTTGA
Protein Properties
Protein Residues: 747
Protein Molecular Weight: 83.8 kDa
Protein Theoretical pI: 7.57
Hydropathicity (GRAVY score): -0.312
Charge at pH 7 (predicted): 4.82
Protein Sequence:
>PA0934
MVQVRAHQPVNTDGSINLEAWLDHVQNLVPGLDRQGLLEACEFARESEQRAIAAQNSWAEGTSSFQTGLEIAEILADLKLDQESLVAAVIYRGVREGKITLEAVNKHFGPVVAKLIEGVLRMAAISASLNPRHSMVLGTQAQVENLRKMLVAMVDDVRVALIKLAERTCAIRAVKNADEEKRHRVAREVFDIYAPLAHRLGIGHIKWELEDLSFRYLEPDQYKQIAKLLHERRLDREQYIANVMSQLKEALAATGVQADLSGRAKHIYSIWRKMQRKGLDFSQIYDVRAVRVLVPEMRDCYTALGIVHTLWRHIPKEFDDYIANPKENGYRSLHTAVIGPEGKVLEVQIRTHSMHEEAELGVCAHWRYKGTDVKASSNHYEEKISWLRQVLEWHEELGDIGGLAEQLRVDIEPDRVYVFTPDGHAIDLPKGATPLDFAYRVHTEVGHNCRGAKINGRIVPLNYSLQTGEQVEIITGKHSGPSRDWLNSNLGYVTTSRARAKIVHWFKLQARDQNVAAGKALIERELSRLALPPVDFDRLAEKANVRTAEDMFAALGAGDLRLAHLVNYAQQLVEPDRDSEQLELIPRKPSKIGHGKRGDVQIQGVGNLLTQMAGCCQPLPGDPIVGYITLGRGVTIHRQDCATALQLAGREPERMIQVSWGPEPVRTYPVDIAIRAYDRSGLLRDVSQVLLNERINVLAVNTRSNKEDNTATMQLTIEIPGLDALGRLLARVSQLPNIIEARRNRTP
References
External Links:
Resource Link
Genome ID: PA0934
Entrez Gene ID: 881299
NCBI Protein ID: 15596131
General Reference: PaperBLAST - Find papers about PA0934 and its homologs