Acetic acid (PAMDB000012)

General function:

Involved in magnesium ion binding

Specific function:

Pyruvate + ferricytochrome b1 + H(2)O = acetate + CO(2) + ferrocytochrome b1

Gene Name:

poxB

Locus Tag:

PA5297

Molecular weight:

62.3 kDa

Reactions

General function:

Involved in kinase activity

Specific function:

Involved in the activation of acetate to acetyl CoA and the secretion of acetate. During anaerobic growth of the organism, this enzyme is also involved in the synthesis of most of the ATP formed catabolically

Gene Name:

ackA

Locus Tag:

PA0836

Molecular weight:

42.4 kDa

Reactions

General function:

Involved in UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity

Specific function:

The key enzyme in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Degraded by FtsH; when the activity of FtsH is reduced too much lipid A and not enough phospholipids are made (both pathways use the same precursor), which is lethal

Gene Name:

lpxC

Locus Tag:

PA4406

Molecular weight:

33.4 kDa

Reactions

General function:

Involved in cysteine biosynthetic process from serine

Specific function:

O(3)-acetyl-L-serine + H(2)S = L-cysteine + acetate

Gene Name:

cysK

Locus Tag:

PA2709

Molecular weight:

34.3 kDa

Reactions

General function:

Involved in cysteine biosynthetic process from serine

Specific function:

Two cysteine synthase enzymes are found. Both catalyze the same reaction. Cysteine synthase B can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product

Gene Name:

cysM

Locus Tag:

PA0932

Molecular weight:

32.4 kDa

Reactions

General function:

Involved in oxidoreductase activity

Specific function:

Involved in the breakdown of putrescine. Was previously shown to have a weak but measurable ALDH enzyme activity that prefers NADP over NAD as coenzyme

Gene Name:

puuC

Locus Tag:

PA5312

Molecular weight:

53.1 kDa

Reactions

General function:

Involved in zinc ion binding

Specific function:

Displays a broad specificity and can also deacylate substrates such as acetylarginine, acetylhistidine or acetylglutamate semialdehyde

Gene Name:

argE

Locus Tag:

PA5206

Molecular weight:

42.2 kDa

Reactions

General function:

Involved in acetate-CoA ligase activity

Specific function:

Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis

Gene Name:

acs

Locus Tag:

PA0887

Molecular weight:

71.8 kDa

Reactions

General function:

Involved in ATP binding

Specific function:

Catalyzes two reactions:the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR; the second, a side reaction, is the production of acetyl phosphate and ADP from acetate and ATP

Gene Name:

purT

Locus Tag:

PA3751

Molecular weight:

42.3 kDa

Reactions

General function:

Involved in oxidoreductase activity

Specific function:

Catalyzes the NADP-dependent oxidation of diverse aldehydes such as chloroacetaldehyde, acetaldehyde, propionaldehyde, benzaldehyde, mafosfamide, 4- hydroperoxycyclophosphamide. Its preferred substrates are acetaldehyde and chloroacetaldehyde

Gene Name:

aldB

Locus Tag:

PA1984

Molecular weight:

54.9 kDa

General function:

Not Available

Specific function:

Not Available

Gene Name:

yjdM

Locus Tag:

PA0128

Molecular weight:

12.1 kDa