Identification |
Name: |
Pyruvate dehydrogenase [cytochrome] |
Synonyms: |
- Pyruvate dehydrogenase [Ubiquinone]
- Pyruvate oxidase
- POX
- Alpha-peptide
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Gene Name: |
poxB |
Enzyme Class: |
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Biological Properties |
General Function: |
Involved in magnesium ion binding |
Specific Function: |
Pyruvate + ferricytochrome b1 + H(2)O = acetate + CO(2) + ferrocytochrome b1 |
Cellular Location: |
Cell membrane; Peripheral membrane protein |
KEGG Pathways: |
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KEGG Reactions: |
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SMPDB Reactions: |
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PseudoCyc/BioCyc Reactions: |
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| + | | + | Ubiquinones | → | | + | Ubiquinols | + | |
| | | | | | | | | pyruvate + a ferricytochrome b1 + H 2O → acetate + CO 2 + a ferrocytochrome b1ReactionCard | | |
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Complex Reactions: |
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Transports: |
Not Available |
Metabolites: |
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GO Classification: |
Function |
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binding | catalytic activity | cation binding | ion binding | magnesium ion binding | metal ion binding | thiamin pyrophosphate binding | transferase activity | vitamin binding |
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Gene Properties |
Locus tag: |
PA5297 |
Strand: |
+ |
Entrez Gene ID: |
881392 |
Accession: |
NP_253984.1 |
GI: |
15600490 |
Sequence start: |
5964859 |
Sequence End: |
5966577 |
Sequence Length: |
1718 |
Gene Sequence: |
>PA5297
ATGTCGAGCAAGAAAGTCGCCGAGATCGTCGTGGAAACCCTGGAAGCCGCCGGCGTCCGCCATTGCTATGGCATCGTCGGCGACACCCTCAACCATGTCACCGACGCCATCCATCGCAGCCAGATCCAGTGGGTCCACGTGCGCCACGAAGAAGCGGCGGCCTTCGCCGCGGGCGCCGAGTCCTACATCAGCGGACGCCTGACCGCCTGCGCCGGCTCCTGCGGACCGGGCAGCCTGCACTTCATCAACGGCGTCTACGAGGCCCAGCGCAACCGCGCGCCGATGGTCCTGATCGCCAGCCAGATCGTCACCCCGCAACTGGGCATGGAGTTTCCCCAGGAGGTCGACTTCAAGGCGGTCTACGCCAGCTGCTCGGTGTTCTGCGAGCAGGTGCACAGCCCGGAACAGGCGCGCCGGGTGGTGGCCCTGGCCTGCCAGGCGGCGCTCAACCGGCGCGGCGTGGCGGTGGTGATCCTGCCGGCCGACATCAGCCAGGCCACGGTGAAGGACGACCTGCCGTTCTCGGTGCATTTCCCGCAACCGGTGCTGCGCCCCAGCGACGCCGAACTGCAGGACGTCGCCCGCCTGCTGGCCCACGGCAAGAAGATCGGCATCTACGCCGGCTCCGGCTGCCAGGGCGCCCACGACCTGCTGGTGGCCCTCGCCGACCGCCTCAAGGCGCCCATCGCGCACACGTCGCGGGCCAAGGACTTCGTCGAGTACGACAACCCCTTCAACATGGGCATGACCGGTATGCTCGGGATCGAGTCCGGCTTCCACATGATGACCGAGTGCGACACCCTCCTGCTGCTCGGCGCCGACTTCGCCTGGGCGCAGTTCTATCCGCAGAAGGCCACCCTGATCCAGGTCGACCGCGATGGCAGTCACCTGGGCCGCCGCCACCCCATCGATCTCGGCGTGGTCGGCGACGTGATCCCCACCCTCGAGGCGCTCTTGCCGTTGCTCGAAGCCCGCGAGGAGCGCAGCTTCCTCGACGAATGCCTGGAGCACCGCGAGCGCTCGCTGCGGACGCTGGAAAAAGAGGAGCAAGCCGGCAAGGGCGAGCTGATCCATCCGCAGCACCTGGTCAGCCTGCTCGACCAGCACGCCAGCGAGGACGCCCTGTTCACCGCCGACGGCGGCTCGGCGATGGTCTGGCTGTTGCGTCACATCCACAGCAACGGCAAGCGCCGCACCCTCACCAGCCTGGTCCACGGCACCATGGCCAACGCCATGCCCCAGGCGCTGGGACTGAAGAAGGCCTACCCCGAGCGCCAGGTAATCTCGATCTCCGGCGACGGCGGCCTGGCCATGCTGCTCGGCGACCTGCTGACGGCCATCCAGGAAAAACTGCCGATCAAGGTAGTGGTGCTGAACAATGCCTCGCTGAACTTCGTCGAGCTGGAACAGAAGGTCGAGGGCCTGCTGGACAACTACACCGACCTGCTCAACCCGGACTTCGCCCGTCTCGCCGAAGTGATCGGCTTCCACGGACGCAAGGTGACGCGCTCCGAGGAGCTCGAGGCGGCGGTGCAGGAGTTCCTCGCCCAGCCCGGTCCGGCGCTGCTGGACGTGCATACCAACCCTGCGGAGCTGGTGATGCCGCCGAAGATCGAGTTCGGCCAGGTCGCCGACACCGCGCTCTACGCCGCCAAGGCCGTGCTCAGCGGGCGCTTCAAGGACGTCGAGACGCTACTGGTGAACAACCTGCTGAAATGA |
Protein Properties |
Protein Residues: |
572 |
Protein Molecular Weight: |
62.3 kDa |
Protein Theoretical pI: |
6.02 |
Hydropathicity (GRAVY score): |
0.006 |
Charge at pH 7 (predicted): |
-12.71 |
Protein Sequence: |
>PA5297
MSSKKVAEIVVETLEAAGVRHCYGIVGDTLNHVTDAIHRSQIQWVHVRHEEAAAFAAGAESYISGRLTACAGSCGPGSLHFINGVYEAQRNRAPMVLIASQIVTPQLGMEFPQEVDFKAVYASCSVFCEQVHSPEQARRVVALACQAALNRRGVAVVILPADISQATVKDDLPFSVHFPQPVLRPSDAELQDVARLLAHGKKIGIYAGSGCQGAHDLLVALADRLKAPIAHTSRAKDFVEYDNPFNMGMTGMLGIESGFHMMTECDTLLLLGADFAWAQFYPQKATLIQVDRDGSHLGRRHPIDLGVVGDVIPTLEALLPLLEAREERSFLDECLEHRERSLRTLEKEEQAGKGELIHPQHLVSLLDQHASEDALFTADGGSAMVWLLRHIHSNGKRRTLTSLVHGTMANAMPQALGLKKAYPERQVISISGDGGLAMLLGDLLTAIQEKLPIKVVVLNNASLNFVELEQKVEGLLDNYTDLLNPDFARLAEVIGFHGRKVTRSEELEAAVQEFLAQPGPALLDVHTNPAELVMPPKIEFGQVADTALYAAKAVLSGRFKDVETLLVNNLLK |
References |
External Links: |
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General Reference: |
PaperBLAST - Find papers about PA5297 and its homologs
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