D-alanine--D-alanine ligase B (PA4410)

Identification
Name: D-alanine--D-alanine ligase B
Synonyms:
  • D-Ala-D-Ala ligase B
  • D-alanylalanine synthetase B
Gene Name: ddlB
Enzyme Class:
Biological Properties
General Function: Involved in ATP binding
Specific Function: Cell wall formation
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
2 Thumb+Thumb ↔ Thumb+Thumb+Thumb+Thumb
2 D-Alanine + Adenosine triphosphate ↔ ADP + D-Alanyl-D-alanine + Hydrogen ion + Phosphate
ReactionCard
Thumb+2 Thumb ↔ Thumb+Thumb+Thumb
Adenosine triphosphate + 2 D-Alanine ↔ ADP + Phosphate + D-Alanyl-D-alanine
ReactionCard
SMPDB Reactions:
2 Thumb+Thumb → Thumb+Adenosine diphosphate+Thumb+Thumb
2 D-Alanine + Adenosine triphosphate → D-Alanyl-D-alanine + Adenosine diphosphate + Phosphate + ADP
ReactionCard
PseudoCyc/BioCyc Reactions:
2 Thumb+Thumb ↔ Thumb+Thumb+Thumb+Thumb
2 D-Alanine + Adenosine triphosphate ↔ ADP + D-Alanyl-D-alanine + Hydrogen ion + Phosphate
ReactionCard
Complex Reactions:
Thumb+2 Thumb → Thumb+Thumb+Thumb
Adenosine triphosphate + 2 D-Alanine → ADP + Inorganic phosphate + D-Alanyl-D-alanine
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB000333D-AlanineMetaboCard
PAMDB000504D-Alanyl-D-alanineMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001776Inorganic phosphateMetaboCard
PAMDB000383PhosphateMetaboCard
GO Classification:
Component
cell part
cell wall
cytoplasm
external encapsulating structure
intracellular part
Function
acid-amino acid ligase activity
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
binding
catalytic activity
D-alanine-D-alanine ligase activity
ligase activity
ligase activity, forming carbon-nitrogen bonds
nucleoside binding
purine nucleoside binding
Process
aminoglycan metabolic process
carbohydrate metabolic process
glycosaminoglycan metabolic process
metabolic process
peptidoglycan biosynthetic process
peptidoglycan metabolic process
polysaccharide metabolic process
primary metabolic process
Gene Properties
Locus tag: PA4410
Strand: -
Entrez Gene ID: 881282
Accession: NP_253100.1
GI: 15599606
Sequence start: 4942677
Sequence End: 4943636
Sequence Length: 959
Gene Sequence: 
>PA4410
ATGAACCTTTGCCTCGATAGCCTGCTGAACGGCACCCAGGATCCCAAGGCGTTCGGCCGTGTCGCCGTGCTGTTCGGCGGCAAGAGCGCCGAGCGCGAGGTGTCGCTGAAGTCCGGCGCGATGGTCCTGCAATCCCTGCTGGCCGCCGGGGTCGATGCCTTCGGCATCGATGTCGGCGAAGACCTGCTGCAACGCCTGGTCGAGGAGAAGATCGACCGTGCCTTCATCATTCTCCACGGTCGTGGCGGCGAGGATGGCAGCATGCAGGGCCTGCTCGAGTGCGCGGGCATTCCCTACACCGGCAGCGGCGTGCTGGCCTCGGCGCTGGCGATGGACAAGCTGCGGACCAAGCGGGTCTGGCTCAGCCTCGGCCTGCCGACCCCGGACTACGCGGTGCTGGCCAGCGAGGATGACTGCCGCGAAGCGGCGCAGCGACTGGGTTTCCCGCTGATCGTCAAGCCGGCTCACGAAGGCTCGAGCATCGGCATGGCCAAGGTCGGCGGGCTCGACGAATTGATCGCGGCGTGGCGCGAAGCGGCCCGCTACGACTCGCAGGTGCTGGTCGAGCAGTGGATCAGCGGCCCGGAATTCACCGTGGCGACCTTGCGCGGGCAGGTGCTGCCGGCGATCCGCCTGGGCACGCCGCACACCTTCTACGACTACGACGCCAAGTACCTGGCCAGCGATACCCGCTACCAGGTGCCCTGCGGTCTCGACGAGGCCAAGGAACGCGAGCTGAAGGAACTCACCGCGCGCGCCTGCGACGCCCTGGGCATCCAGGGCTGGGGGCGGGCGGACGTGATGCAGGACGCCGAAGGGCGTTTCTGGCTGCTTGAAGTCAACACCGCACCGGGCATGACCGACCACAGCCTGGTGCCTATGGCCGCGCGGGCCGCCGGCCTGGATTTCCAGCAACTGGTGCTGGCGATCCTGGCCGATAGCCGCGAGGCGAGGGGATAA
Protein Properties
Protein Residues: 319
Protein Molecular Weight: 34.4 kDa
Protein Theoretical pI: 4.66
Hydropathicity (GRAVY score): -0.005
Charge at pH 7 (predicted): -11.18
Protein Sequence: 
>PA4410
MNLCLDSLLNGTQDPKAFGRVAVLFGGKSAEREVSLKSGAMVLQSLLAAGVDAFGIDVGEDLLQRLVEEKIDRAFIILHGRGGEDGSMQGLLECAGIPYTGSGVLASALAMDKLRTKRVWLSLGLPTPDYAVLASEDDCREAAQRLGFPLIVKPAHEGSSIGMAKVGGLDELIAAWREAARYDSQVLVEQWISGPEFTVATLRGQVLPAIRLGTPHTFYDYDAKYLASDTRYQVPCGLDEAKERELKELTARACDALGIQGWGRADVMQDAEGRFWLLEVNTAPGMTDHSLVPMAARAAGLDFQQLVLAILADSREARG
References
External Links:
Resource Link
Genome ID: PA4410
Entrez Gene ID: 881282
NCBI Protein ID: 15599606
General Reference: PaperBLAST - Find papers about PA4410 and its homologs