Identification |
Name: |
NADH-quinone oxidoreductase subunit H |
Synonyms: |
- NADH dehydrogenase I subunit H
- NDH-1 subunit H
- NUO8
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Gene Name: |
nuoH |
Enzyme Class: |
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Biological Properties |
General Function: |
Involved in oxidation-reduction process |
Specific Function: |
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone |
Cellular Location: |
Cell inner membrane; Multi-pass membrane protein |
KEGG Pathways: |
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KEGG Reactions: |
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| + | Acceptor | ↔ | | + | Reduced acceptor |
| | | |
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SMPDB Reactions: |
| | |
| + | 4 | + | 2 | + | menaquinone-8 | ? | | + | | + | | + | Electron | + | 4 |
| | |
"a menaquinone" | + | 4 | + | | → | "a menaquinol" | + | |
| | |
4 | + | | + | "a menaquinone" | → | | + | "a menaquinol" |
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PseudoCyc/BioCyc Reactions: |
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Complex Reactions: |
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Transports: |
Not Available |
Metabolites: |
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GO Classification: |
Component |
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cell part | membrane | Process |
---|
metabolic process | oxidation reduction |
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Gene Properties |
Locus tag: |
PA2643 |
Strand: |
+ |
Entrez Gene ID: |
882350 |
Accession: |
NP_251333.1 |
GI: |
15597839 |
Sequence start: |
2990435 |
Sequence End: |
2991430 |
Sequence Length: |
995 |
Gene Sequence: |
>PA2643
ATGAGTTGGCTGACTCCCGCTCTGGTCACCATCATCCTCACCGTGGTCAAGGCCATCGTGGTGCTGCTCGCCGTGGTCATCTGCGGCGCCCTGCTAAGCTGGGTCGAGCGCCGCCTGCTCGGCCTCTGGCAGGACCGCTACGGCCCCAACCGGGTCGGTCCGTTCGGTGCGTTCCAGCTCGGCGCGGACATGGTCAAGATGTTCTTCAAGGAGGACTGGACCCCGCCGTTCGCCGACAAGATGATCTTCACCCTGGCCCCGGTAATCGCGATGGGCGCCCTGCTCGTCGCCTTCGCCATCGTGCCGATCACCCCCACCTGGGGCGTGGCGGACCTGAACATCGGCATCCTGTTCTTCTTCGCCATGGCCGGCCTGACGGTGTACGCCGTGCTGTTCGCCGGCTGGTCGAGCAACAACAAGTTCGCCCTGCTCGGCAGCCTGCGCGCCTCGGCCCAGACCATCTCCTACGAGGTGTTCCTGGCCCTGTCGCTGATGGGCATCGTCGCCCAGGTCGGCTCGTTCAACATGCGCGACATCGTCCAGTACCAGATCGACAACGTCTGGTTCATCATTCCGCAGTTCTTCGGCTTCTGCACCTTCATCATCGCCGGCGTCGCCGTGACCCACCGTCACCCGTTCGACCAGCCGGAAGCGGAGCAGGAACTGGCGGACGGCTACCACATCGAGTACGCCGGGATGAAATGGGGCATGTTCTTCGTCGGCGAGTACATCGGCATCGTACTGGTCTCGGCGCTGCTGGCGACCCTGTTCTTCGGCGGCTGGCACGGTCCGTTCCTGGACACCCTGCCCTGGCTGTCGTTCTTCTACTTCGCCGCCAAGACCGGCTTCTTCATCATGCTCTTCATCCTGATCCGCGCCTCGCTGCCGCGTCCGCGCTATGACCAGGTGATGGCGTTCAGCTGGAAGGTGTGCCTGCCGCTGACCCTGATCAACCTGCTGGTGACCGGCGCGCTCGTGCTGGCCGCGGCCCAGTAA |
Protein Properties |
Protein Residues: |
331 |
Protein Molecular Weight: |
36.7 kDa |
Protein Theoretical pI: |
6.93 |
Hydropathicity (GRAVY score): |
0.867 |
Charge at pH 7 (predicted): |
-0.14 |
Protein Sequence: |
>PA2643
MSWLTPALVTIILTVVKAIVVLLAVVICGALLSWVERRLLGLWQDRYGPNRVGPFGAFQLGADMVKMFFKEDWTPPFADKMIFTLAPVIAMGALLVAFAIVPITPTWGVADLNIGILFFFAMAGLTVYAVLFAGWSSNNKFALLGSLRASAQTISYEVFLALSLMGIVAQVGSFNMRDIVQYQIDNVWFIIPQFFGFCTFIIAGVAVTHRHPFDQPEAEQELADGYHIEYAGMKWGMFFVGEYIGIVLVSALLATLFFGGWHGPFLDTLPWLSFFYFAAKTGFFIMLFILIRASLPRPRYDQVMAFSWKVCLPLTLINLLVTGALVLAAAQ |
References |
External Links: |
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General Reference: |
PaperBLAST - Find papers about PA2643 and its homologs
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