| Identification |
| Name: |
Isocitrate dehydrogenase [NADP] |
| Synonyms: |
- IDH
- IDP
- NADP(+)-specific ICDH
- Oxalosuccinate decarboxylase
|
| Gene Name: |
icd |
| Enzyme Class: |
|
| Biological Properties |
| General Function: |
Involved in magnesium ion binding |
| Specific Function: |
Isocitrate + NADP(+) = 2-oxoglutarate + CO(2) + NADPH |
| Cellular Location: |
Not Available |
| KEGG Pathways: |
- Citrate cycle (TCA cycle) pae00020
- Glutathione metabolism pae00480
- Metabolic pathways pae01100
- Microbial metabolism in diverse environments pae01120
- Reductive carboxylate cycle (CO2 fixation) pae00720
|
| KEGG Reactions: |
|
| SMPDB Reactions: |
|
| PseudoCyc/BioCyc Reactions: |
|
| Complex Reactions: |
Not Available |
| Transports: |
Not Available |
| Metabolites: |
|
| GO Classification: |
| Function |
|---|
| binding | | catalytic activity | | cation binding | | ion binding | | isocitrate dehydrogenase (NADP+) activity | | isocitrate dehydrogenase activity | | magnesium ion binding | | metal ion binding | | NAD or NADH binding | | nucleotide binding | | oxidoreductase activity | | oxidoreductase activity, acting on CH-OH group of donors | | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | | Process |
|---|
| acetyl-CoA catabolic process | | acetyl-CoA metabolic process | | cellular metabolic process | | coenzyme metabolic process | | cofactor metabolic process | | metabolic process | | oxidation reduction | | tricarboxylic acid cycle |
|
| Gene Properties |
| Locus tag: |
PA2623 |
| Strand: |
- |
| Entrez Gene ID: |
882329 |
| Accession: |
NP_251313.1 |
| GI: |
15597819 |
| Sequence start: |
2965546 |
| Sequence End: |
2966802 |
| Sequence Length: |
1256 |
| Gene Sequence: |
>PA2623
ATGGGATACCAAAAGATCCAGGTGCCGGCGACCGGTGACAAAATCACTGTGAATGCCGACATGTCCTTGAGCGTACCGAAGAACCCGATCATCCCGTTCATCGAGGGTGATGGCATCGGCGTCGATATCAGCCCGGTCATGATCAAGGTTGTCGACGCTGCAGTGGAAAAAGCATACAAGGGCGAGCGCAAGATCGCCTGGATGGAAGTCTACGCCGGCGAGAAGGCCACCCAGGTCTATGACCAGGACACCTGGCTGCCCCAGGAAACCCTGGACGCCGTACGCGACTACGTGGTTTCCATCAAGGGCCCGCTGACCACCCCGGTCGGTGGCGGCATCCGCTCCCTGAACGTGGCCCTGCGCCAGCAACTCGATCTCTACGTCTGCCAGCGCCCGGTACGCTGGTTCGAAGGCGTGCCCAGCCCGGTGAAGAAGCCCGGCGACGTGGACATGGTGATCTTCCGCGAGAACTCCGAGGACATCTATGCCGGCGTCGAGTGGAAGGCCGGTTCGCCGGAAGCGGAGAAGGTCATCAAGTTCCTCACCGAGGAAATGGGCGTCAAGAAGATCCGCTTCACCGAGAACTGCGGCATCGGCATCAAGCCGGTTTCCCAGGAAGGCACCAAGCGCCTGGTGCGCAAGGCCCTGCAATACGCCGTCGACAACGACCGCAGTTCGGTGACCCTGGTGCACAAGGGCAACATCATGAAGTTCACCGAGGGTGCCTTCAAGGATTGGGGCTACGAAGTCGCGCGCGATGAATTCGGCGCCGAGCTGCTGGACGGCGGTCCGTGGATGCAGTTCAAGAATCCGAAGACCGGCAAGAACGTCGTGGTCAAGGACGTGATCGCCGACGCCATGTTGCAGCAGATCCTGCTGCGCCCCGCCGAGTACGACGTGATCGCCACCCTGAACCTGAACGGCGACTATCTCTCCGACGCCCTGGCGGCCGAGGTCGGCGGCATCGGCATCGCGCCCGGCGCCAACCTGTCCGATTCGGTGGCCATGTTCGAGGCGACCCACGGCACCGCGCCGAAGTACGCCGGCCAGGACAAGGTCAACCCGGGTTCGCTGATCCTCTCCGCGGAGATGATGCTGCGCCACATGGGTTGGACCGAGGCGGCCGACCTGATCATCAAGGGCACCAACGGGGCGATCGCCGCCAAGACCGTGACCTATGACTTCGAACGCCTGATGGACGGCGCGACCCTGCTGTCCTGCTCGGAGTTCGGCGACGCGATGATTGCCAAGATGTAG |
| Protein Properties |
| Protein Residues: |
418 |
| Protein Molecular Weight: |
45.6 kDa |
| Protein Theoretical pI: |
4.85 |
| Hydropathicity (GRAVY score): |
-0.116 |
| Charge at pH 7 (predicted): |
-9.35 |
| Protein Sequence: |
>PA2623
MGYQKIQVPATGDKITVNADMSLSVPKNPIIPFIEGDGIGVDISPVMIKVVDAAVEKAYKGERKIAWMEVYAGEKATQVYDQDTWLPQETLDAVRDYVVSIKGPLTTPVGGGIRSLNVALRQQLDLYVCQRPVRWFEGVPSPVKKPGDVDMVIFRENSEDIYAGVEWKAGSPEAEKVIKFLTEEMGVKKIRFTENCGIGIKPVSQEGTKRLVRKALQYAVDNDRSSVTLVHKGNIMKFTEGAFKDWGYEVARDEFGAELLDGGPWMQFKNPKTGKNVVVKDVIADAMLQQILLRPAEYDVIATLNLNGDYLSDALAAEVGGIGIAPGANLSDSVAMFEATHGTAPKYAGQDKVNPGSLILSAEMMLRHMGWTEAADLIIKGTNGAIAAKTVTYDFERLMDGATLLSCSEFGDAMIAKM |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA2623 and its homologs
|
