P. aeruginosa Metabolome Database Protein PA2341

Identification

Name:

Maltose/maltodextrin import ATP-binding protein MalK

Synonyms:

Not Available

Gene Name:

malK

Enzyme Class:

3.6.3.19

Biological Properties

General Function:

Involved in nucleotide binding

Specific Function:

Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system

Cellular Location:

Cell inner membrane; Peripheral membrane protein

KEGG Pathways:

Starch and sucrose metabolism PW000941
ABC transporters pae02010

KEGG Reactions:

Not Available

SMPDB Reactions:

→

Adenosine diphosphate

Maltotetraose + Adenosine triphosphate + Water → Maltotetraose + Phosphate + Hydrogen ion + Adenosine diphosphate + ADP
ReactionCard

→

Adenosine diphosphate

Maltotriose + Adenosine triphosphate + Water → Adenosine diphosphate + Phosphate + Hydrogen ion + Maltotriose + ADP
ReactionCard

→

Adenosine diphosphate

D-Maltose + Adenosine triphosphate + Water → D-Maltose + Phosphate + Hydrogen ion + Adenosine diphosphate + ADP
ReactionCard

PseudoCyc/BioCyc Reactions:

→

Adenosine triphosphate + Water + D-Maltose → ADP + Hydrogen ion + D-Maltose + Phosphate
ReactionCard

→

Adenosine triphosphate + Water + Maltotriose → ADP + Hydrogen ion + Maltotriose + Phosphate
ReactionCard

→

Adenosine triphosphate + Water + Maltotetraose → ADP + Hydrogen ion + Maltotetraose + Phosphate
ReactionCard

Complex Reactions:

→

Adenosine triphosphate + Water + 1,4-alpha-D-glucan → 1,4-alpha-D-glucan + ADP + Hydrogen ion + Phosphate
ReactionCard

→

Adenosine triphosphate + Water + Maltohexaose → ADP + Hydrogen ion + Maltohexaose + Phosphate
ReactionCard

→

Adenosine triphosphate + Water + Maltopentaose → ADP + Hydrogen ion + Maltopentaose + Phosphate
ReactionCard

→

Adenosine triphosphate + Water + D-Maltose → ADP + Inorganic phosphate + D-Maltose
ReactionCard

Transports:

Not Available

Metabolites:

PAMDB ID	Name	View
PAMDB001519	1,4-alpha-D-glucan	MetaboCard
PAMDB000148	Adenosine triphosphate	MetaboCard
PAMDB000345	ADP	MetaboCard
PAMDB000065	D-Maltose	MetaboCard
PAMDB001633	Hydrogen ion	MetaboCard
PAMDB001776	Inorganic phosphate	MetaboCard
PAMDB001651	Maltohexaose	MetaboCard
PAMDB001652	Maltopentaose	MetaboCard
PAMDB000327	Maltotetraose	MetaboCard
PAMDB000315	Maltotriose	MetaboCard
PAMDB000383	Phosphate	MetaboCard
PAMDB000142	Water	MetaboCard

GO Classification:

Component
ATP-binding cassette (ABC) transporter complex
cell part
macromolecular complex
membrane
protein complex
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
alpha-glucoside transmembrane transporter activity
ATP binding
ATPase activity
binding
carbohydrate transmembrane transporter activity
catalytic activity
glucoside transmembrane transporter activity
hydrolase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
maltose transmembrane transporter activity
maltose-transporting ATPase activity
nucleoside binding
nucleoside-triphosphatase activity
nucleotide binding
purine nucleoside binding
pyrophosphatase activity
substrate-specific transmembrane transporter activity
sugar transmembrane transporter activity
transmembrane transporter activity
transporter activity
Process
alpha-glucoside transport
carbohydrate transport
establishment of localization
glucoside transport
maltose transport
transport

Gene Properties

Locus tag:

PA2341

Strand:

Entrez Gene ID:

878622

Accession:

NP_251031.1

GI:

15597537

Sequence start:

2585299

Sequence End:

2586411

Sequence Length:

1112

Gene Sequence:

>PA2341
ATGGCTGATCTCAAGATCCGCAACCTGCAGAAAGGCTTCGACGGCCAGGCCATCATCAAGGGCATCGACCTCGACGTCCGCGACCGCGAGTTCGTAGTCTTCGTCGGCCCCTCCGGCTGCGGCAAGTCGACCCTGCTGCGCCTGATCGCCGGCCTCGAAGAGGCCAGCGGCGGCAGCATCGCCCTCGACGGCACGGACATCACCGACACCCCGCCGGCGAAACGCGACCTGGCGATGGTCTTCCAGACCTACGCGCTGTACCCGCACATGACGGTGCGCAGGAACCTCTCCTTCGCCCTCGACCTGGCCGGCGTCGACAAGCGCGAGGTCGCCGCCAAGGTCGACGCCGCCGCACGCATCCTCGAACTGCAAGCGCTGCTGGAGCGCAAGCCGCGCCAGCTCTCCGGCGGCCAACGGCAGCGGGTGGCGATCGGCCGGGCGATCGTGCGCAACCCGAAGATATTCCTCTTCGACGAACCGCTGTCCAACCTCGACGCCGCCCTGCGCGTGCAGATGCGCCTGGAACTGGCGCGGCTGCACCAGGAACTGGCGGCGACCATGATCTACGTGACCCACGACCAGGTCGAGGCGATGACCCTGGCGGACAAGGTCGTGGTGCTCAACGGCGGGCGCGTCGAGCAGGTCGGCTCGCCGCTGGAGCTTTACCACCATCCGGCCAACCTGTTCGTCGCCGGCTTCCTCGGCACGCCGAAGATGGGCTTCCTGCGCGGCCATCTCAGCCGCAACCAGGGCGAGCGCTGCGAGGTCGCCCTCGAATGCGGCGCGCGCGTCGGCCTGCCGCTATGCGCCGGCGAGCTGGCCACCGGCAGCCCGGTGACCCTCGGCATCCGCCCGGAACACCTGAACATCGCCCGCCCGGGCCATGCCTTCCAGGGCCTGCTGCGGGTCGCCGCCGACGTCAGCGAGCGCCTGGGCAGCGACAGCTTCTGCCATGTCCGCGCCGACTCGGGGGAAATGCTCACCCTGCGCGTGCGCGGCGATTTCGCACCGGACTACGGCGCCCCCCTGGAGCTGGGCTTCGATCCGGAGCACTGCCACCTGTTCGACAGCAACGGCCAGGCCCTCGACAAACGACTGCAACAGGCGGCCTGA

Protein Properties

Protein Residues:

370

Protein Molecular Weight:

40.2 kDa

Protein Theoretical pI:

7.09

Hydropathicity (GRAVY score):

-0.062

Charge at pH 7 (predicted):

0.47

Protein Sequence:

>PA2341
MADLKIRNLQKGFDGQAIIKGIDLDVRDREFVVFVGPSGCGKSTLLRLIAGLEEASGGSIALDGTDITDTPPAKRDLAMVFQTYALYPHMTVRRNLSFALDLAGVDKREVAAKVDAAARILELQALLERKPRQLSGGQRQRVAIGRAIVRNPKIFLFDEPLSNLDAALRVQMRLELARLHQELAATMIYVTHDQVEAMTLADKVVVLNGGRVEQVGSPLELYHHPANLFVAGFLGTPKMGFLRGHLSRNQGERCEVALECGARVGLPLCAGELATGSPVTLGIRPEHLNIARPGHAFQGLLRVAADVSERLGSDSFCHVRADSGEMLTLRVRGDFAPDYGAPLELGFDPEHCHLFDSNGQALDKRLQQAA

References

External Links:

Resource	Link
Genome ID:	PA2341
Entrez Gene ID:	878622
NCBI Protein ID:	15597537

General Reference:

PaperBLAST - Find papers about PA2341 and its homologs

Maltose/maltodextrin import ATP-binding protein MalK (PA2341)