Catalase HPII (PA2147)

Identification
Name: Catalase HPII
Synonyms:
  • Hydroxyperoxidase II
Gene Name: katE
Enzyme Class:
Biological Properties
General Function: Involved in catalase activity
Specific Function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide
Cellular Location: Cytoplasm (Probable)
KEGG Pathways:
KEGG Reactions:
2 Thumb ↔ 2 Thumb+Thumb
2 Hydrogen peroxide ↔ 2 Water + Oxygen
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Thumb+Thumb ↔ Thumb+2 Thumb
Methanol + Hydrogen peroxide ↔ Formaldehyde + 2 Water
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2 Thumb+4 Thumb ↔ Thumb+2 Thumb+2 Thumb+2 Thumb
2 3-Hydroxyanthranilic acid + 4 Oxygen ↔ Cinnavalininate + 2 Superoxide anion + 2 Hydrogen peroxide + 2 Hydrogen ion
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SMPDB Reactions:
Thumb+Thumb → Thumb
ferroheme b + Hydrogen peroxide → Heme D
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2 Thumb → 2 Thumb+Thumb
2 Hydrogen peroxide → 2 Water + Oxygen
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PseudoCyc/BioCyc Reactions:
2 Thumb ↔ 2 Thumb+Thumb
2 Hydrogen peroxide ↔ 2 Water + Oxygen
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Complex Reactions:
2 Thumb → Thumb+2 Thumb
2 Hydrogen peroxide → Oxygen + 2 Water
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Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0003963-Hydroxyanthranilic acidMetaboCard
PAMDB001425CinnavalininateMetaboCard
PAMDB006369ferroheme bMetaboCard
PAMDB000382FormaldehydeMetaboCard
PAMDB001368Heme DMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001640Hydrogen peroxideMetaboCard
PAMDB000425MethanolMetaboCard
PAMDB000624OxygenMetaboCard
PAMDB001691Superoxide anionMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
antioxidant activity
binding
catalase activity
cation binding
heme binding
ion binding
iron ion binding
metal ion binding
peroxidase activity
transition metal ion binding
Process
metabolic process
oxidation reduction
response to oxidative stress
response to stimulus
response to stress
Gene Properties
Locus tag: PA2147
Strand: +
Entrez Gene ID: 881554
Accession: NP_250837.1
GI: 15597343
Sequence start: 2361954
Sequence End: 2364083
Sequence Length: 2129
Gene Sequence: 
>PA2147
ATGAGCGAGCAGAACAACGAGCAGCGCAGCCAGGCGGCCGGCACCGACACCGTCGACCGTGGCAACAGCAACGCCAAGCTGGAACAGCTGGAGGCCTATCGCGAGGACGCCACCGGAGAGGCCCTGAGCACCAATACCGGCACCCGCATCGCCGATAACCAGAACACCCTGAAGGCCGGCGAGCGCGGACCGTCGTTGCTCGAAGACTTCATCATGCGCGAGAAGATCACCCACTTCGACCACGAGCGCATTCCCGAGCGCGTGGTCCACGCTCGTGGCTCGGCGGCGCATGGCTACTTCGAGGCCTACGAGGACCTCAGCGACCTGACCAAGGCCGGCTTCCTCGCCGAGGCGGGCAAGCGTACCCCGGTCTTCGTGCGTTTCTCCACCGTGCAGGGGCCGCGCGGGTCCGCGGATACGGTGCGTGACGTACGCGGCTTCGCCGTGAAGTTCTATACCGACGAAGGCAACTTCGACCTGGTCGGCAACAACATGCCGGTGTTCTTCATCCAGGATGCGATCAAGTTCCCCGACTTCGTCCATGCGGTGAAACCCGAACCGCACAACGAGATTCCCACCGGAGCGTCTGCCCACGACACCTTCTGGGACTTCGTTTCGCTGACCCCGGAGTCGGCGCACATGGTCATGTGGCTGATGTCCGATCGCGCCATTCCGATCGCCTACCGCAACATGCAGGGCTTCGGCGTGCACACCTTCCGCCTGGTCAACGCGGCCGGCGAGAGCGTGCTGGTCAAGTTCCACTGGCGACCGAAGTCCGGGACCTGCTCGCTGGTCTGGGACGAGGCGCAGAAGCTCGCCGGCAAGGACCCCGACTTCAACCGGCGGACCCTCTGGGAGGACATCGAGAAGGGCGACTATCCCGAATGGGAGCTGGGCCTGCAGGTGATCCCGGAGAACCAGCAGGACAGCTTCGACTTCGACCTGCTCGACCCCACCAAGCTGGTGCCCGAGGAGTTGGTGCCGGTAAGGGTGGTGGGGCGGATGGTACTCAACCGCAACCCCGACAATTTCTTCGCCGAGACCGAACAGGTGGCGTTCCACGTCGGCCACGTGGTCCCCGGAATCGACTTCACCAACGACCCGCTGTTGCAGGGTCGGCTGTTCTCCTATACCGACACCCAACTGCTGCGCCTGAGCGGGCCGAACTTCAACGAAATCCCGATCAACCGCCCGCTGTGTCCGTTCCACAACAACCAGCGCGACGCGCCGCACCGGCAGACCATCAACCGCGGCCGGGCTTCCTATGAACCGAACTCGATCGACGGCGGCTGGCCGAAGGAAACCCCGCCGGCGGCGCGCAACGGCGGCTTCTCCACCTACCACGAGCCGGTCAGCGGCAGCAAGCTGCGCAAGCGTGCCGACTCCTTCGCCGATCATTTCAGCCAGGCCGCATTGTTCTGGCACAGCATGAGCGAGGCCGAGCAGGCGCATATCGTCGCCGCCTACAGCTTCGAACTGTCCAAGGTCGAGCGGCAATCGATCCGTGAGCGCGAAGTCAACCAGATACTCCTCAACATCGATCCGCAACTGGCCGCCAGGGTCGCGGCGAACGTCGGTGTGCAGCTCGCCGCGCCGGCCAACCCGACACCGCAGCCGAAGCCGTCGCCGGCGCTGAGCCAGATGAATCTGCTGTCCGGCGACATCCGTTCGCGCAAGGTGGCGATCCTGATCGCCGACGGCGTCGCCGAGAGCGACGTCAGCGACCTGCGCGACGCGCTCCGCCAGGAGGGCGCGGACGCCAAGCTGATCGCGCCCAGCGCTTCGCCGGTGCAGGCTGAAAACGGCGCCGAACTGAGCCCTGAGGGAACCTGGGACGGCCTGCCGTCGGTAGCCTTCGACGCGGTCTTCGTGCCTGGCGGCGCGGCCAGCAGCCAGGCCATCGGCGCTGACGGGCGCGGCCTGCACTACCTGCTGGAAGCCTACAAGCACCTGAAGCCAGTGGCCTTCGCCGGCGATGCCCAGGCGCTGGCCAGCCAGCTTTCGTTGCCTGGCGACCCCGGCGTGGTGCTCGGCGCCACGGCCACCGATGTCTTCCCCGGCCTGCGCCAGGCATTGATGCAGCACCGGATCTGGCAGCGCGAGGCGGCGACCAAGGCGATCCCCGCCTGA
Protein Properties
Protein Residues: 709
Protein Molecular Weight: 78 kDa
Protein Theoretical pI: 5.32
Hydropathicity (GRAVY score): -0.401
Charge at pH 7 (predicted): -18.96
Protein Sequence: 
>PA2147
MSEQNNEQRSQAAGTDTVDRGNSNAKLEQLEAYREDATGEALSTNTGTRIADNQNTLKAGERGPSLLEDFIMREKITHFDHERIPERVVHARGSAAHGYFEAYEDLSDLTKAGFLAEAGKRTPVFVRFSTVQGPRGSADTVRDVRGFAVKFYTDEGNFDLVGNNMPVFFIQDAIKFPDFVHAVKPEPHNEIPTGASAHDTFWDFVSLTPESAHMVMWLMSDRAIPIAYRNMQGFGVHTFRLVNAAGESVLVKFHWRPKSGTCSLVWDEAQKLAGKDPDFNRRTLWEDIEKGDYPEWELGLQVIPENQQDSFDFDLLDPTKLVPEELVPVRVVGRMVLNRNPDNFFAETEQVAFHVGHVVPGIDFTNDPLLQGRLFSYTDTQLLRLSGPNFNEIPINRPLCPFHNNQRDAPHRQTINRGRASYEPNSIDGGWPKETPPAARNGGFSTYHEPVSGSKLRKRADSFADHFSQAALFWHSMSEAEQAHIVAAYSFELSKVERQSIREREVNQILLNIDPQLAARVAANVGVQLAAPANPTPQPKPSPALSQMNLLSGDIRSRKVAILIADGVAESDVSDLRDALRQEGADAKLIAPSASPVQAENGAELSPEGTWDGLPSVAFDAVFVPGGAASSQAIGADGRGLHYLLEAYKHLKPVAFAGDAQALASQLSLPGDPGVVLGATATDVFPGLRQALMQHRIWQREAATKAIPA
References
External Links:
Resource Link
Genome ID: PA2147
Entrez Gene ID: 881554
NCBI Protein ID: 15597343
General Reference: PaperBLAST - Find papers about PA2147 and its homologs