Glutaminyl-tRNA synthetase (PA1794)

Identification
Name: Glutaminyl-tRNA synthetase
Synonyms:
  • Glutamine--tRNA ligase
  • GlnRS
Gene Name: glnS
Enzyme Class:
Biological Properties
General Function: Involved in nucleotide binding
Specific Function: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+tRNA(Gln)+tRNA(Gln) ↔ Thumb+Thumb+Glutaminyl-tRNA+Glutaminyl-tRNA
Adenosine triphosphate + L-Glutamine + tRNA(Gln) + tRNA(Gln) ↔ Adenosine monophosphate + Pyrophosphate + Glutaminyl-tRNA + Glutaminyl-tRNA
ReactionCard
SMPDB Reactions:
Thumb+Thumb+Thumb+tRNA(Gln) → Adenosine diphosphate+Pyrophosphate+L-Glutaminyl-tRNA(Gln)+Thumb
L-Glutamine + Adenosine triphosphate + Hydrogen ion + tRNA(Gln) → Adenosine diphosphate + Pyrophosphate + L-Glutaminyl-tRNA(Gln) + ADP
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+tRNA(Gln) → Thumb+L-Glutaminyl-tRNA(Gln)+Thumb
Adenosine triphosphate + L-Glutamine + tRNA(Gln) → Adenosine monophosphate + L-Glutaminyl-tRNA(Gln) + Pyrophosphate
ReactionCard
Thumb+Thumb+tRNA(Gln)+tRNA(Gln) ↔ Thumb+Thumb+Glutaminyl-tRNA+Glutaminyl-tRNA
Adenosine triphosphate + L-Glutamine + tRNA(Gln) + tRNA(Gln) ↔ Adenosine monophosphate + Pyrophosphate + Glutaminyl-tRNA + Glutaminyl-tRNA
ReactionCard
Thumb+Thumb+tRNA(Gln) → Thumb+Thumb+L-glutaminyl-tRNA(Gln)
Adenosine triphosphate + L-Glutamine + tRNA(Gln) → Adenosine monophosphate + Pyrophosphate + L-glutaminyl-tRNA(Gln)
ReactionCard
Thumb+Thumb+Thumb+tRNA(Gln) → Adenosine diphosphate+Pyrophosphate+L-Glutaminyl-tRNA(Gln)+Thumb
L-Glutamine + Adenosine triphosphate + Hydrogen ion + tRNA(Gln) → Adenosine diphosphate + Pyrophosphate + L-Glutaminyl-tRNA(Gln) + ADP
ReactionCard
Thumb
a tRNAgln + L-glutamine + ATP + H+ → an L-glutaminyl-[tRNAgln] + AMP + diphosphate
ReactionCard
Complex Reactions:
Thumb+Thumb+tRNA(Gln) → Thumb+L-Glutaminyl-tRNA(Gln)+Thumb
Adenosine triphosphate + L-Glutamine + tRNA(Gln) → Adenosine monophosphate + L-Glutaminyl-tRNA(Gln) + Pyrophosphate
ReactionCard
Thumb+Thumb+tRNA(Gln) → Thumb+Thumb+L-glutaminyl-tRNA(Gln)
Adenosine triphosphate + L-Glutamine + tRNA(Gln) → Adenosine monophosphate + Pyrophosphate + L-glutaminyl-tRNA(Gln)
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000014Adenosine monophosphateMetaboCard
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000163L-GlutamineMetaboCard
PAMDB000633PyrophosphateMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
aminoacyl-tRNA ligase activity
ATP binding
binding
catalytic activity
glutamine-tRNA ligase activity
ligase activity
ligase activity, forming aminoacyl-tRNA and related compounds
ligase activity, forming carbon-oxygen bonds
nucleoside binding
nucleotide binding
purine nucleoside binding
Process
biosynthetic process
cellular macromolecule biosynthetic process
cellular macromolecule metabolic process
glutaminyl-tRNA aminoacylation
macromolecule biosynthetic process
macromolecule metabolic process
metabolic process
ncRNA metabolic process
RNA metabolic process
translation
tRNA aminoacylation
tRNA aminoacylation for protein translation
tRNA metabolic process
Gene Properties
Locus tag: PA1794
Strand: +
Entrez Gene ID: 878828
Accession: NP_250485.1
GI: 15596991
Sequence start: 1943067
Sequence End: 1944737
Sequence Length: 1670
Gene Sequence: 
>PA1794
ATGAGCAAGCCAGAGACCACCGCCGCCCCGAACTTCCTGCGCCAGATCGTTCAAGCCGACCTGGATGCCGGCAAGCACGCGAAGATCGTCACCCGTTTCCCCCCGGAGCCCAACGGTTACCTGCACATCGGCCACGCCAAGTCGATCTGCCTGAACTTCGGCCTGGCCCAGGAATTCGCTGGCGATTGCCATCTGCGCTTCGATGACACCAACCCGGCCAAGGAAGACCAGGAGTACATCGATGCCATCGAGGCCGACATCAAGTGGCTGGGCTTCCAGTGGTCCGGCGAGGTCTGCTATGCCTCCAACTATTTCGACCAGCTGCATGCCTGGGCCGTCGAGCTGATCAAGGCCGGCAAGGCGTTCGTCTGCGACCTCGGTCCCGAGGAAATGCGCGAATACCGCGGCACCCTCACCGAGCCGGGCCGCAACAGCCCTTACCGTGACCGTTCGGTGGAGGAGAACCTCGACCTGTTCGCCCGCATGAAGGCCGGTGAGTTCCCCGACGGCGCCCGTTCGCTGCGGGCGAAGATCGACATGGGTTCGCCGAACATGAACCTGCGCGATCCGATCCTGTACCGCATCCGCCATGCGCATCACCACCAGACCGGCGACAAGTGGTGCATCTACCCGAGCTACGACTTCACCCACGGTCAGTCGGACGCCATCGAGGGCATCACCCATTCGATCTGCACCCTGGAATTCGAAGACCATCGTCCGCTCTACGAGTGGTTCCTGGCCAACCTGCCGGTACCTGCGCAACCGCGCCAGTACGAATTCTCCCGGCTCAACCTGAACTACACCGTGACCAGCAAGCGCAAGCTCAAGCAATTGGTCGACGAAGGCCATGTCAGCGGCTGGGACGATCCGCGCATGTCGACCCTGTCCGGCTATCGCCGCCGCGGCTACACCCCGGAGTCGATCCGCAACTTCTGCGAGATGATCGGGGTGAACCGCGCCAGCGGCGTGGTCGACATCGGCATGCTCGAGTTCAGCATCCGCGACCACCTGGACGCCACCGCGCCGCGTGCCATGTGCGTGCTGAAACCGCTCAAGGTGGTGATCACCAACTACCCCGAAGGGCAGGTGGAGAACCTCGAGTTGCCGCGTCATCCGAAGGAAGACATGGGAGTGCGCGTACTGCCGTTCGGTCGCGAGCTGTTCATCGATGCCGGTGACTTCGAGGAAGTCCCGCCGGCCGGCTACAAGCGCCTGATCCCCGGTGGCGAGGTGCGTCTGCGCGGCAGCTACGTGATCCGTGCCGACGAAGCGATCAAGGATGCCGACGGCAATATCGTCGAACTGCGCTGCAGCTACGATCCGGACACCCTGGGCAAGAACCCGGAAGGCCGCAAGGTCAAGGGCGTGATCCACTGGGTGCCGGCCGAGGGCAGCGTCGAGTGCGAAGTGCGCCTGTACGATCGGCTGTTCCGCTCGGCCAATCCGGAGAAGGCGGAAGAGGGCGGCAGCTTCCTCGACAACATCAACGCCGACTCCCTGCAGGTACTGGCCGGCTGTCGCGCCGAGCCGTCGCTGGGCCAGGCGAACCCGGAGGATCGCTTCCAGTTCGAGCGCGAAGGCTATTTCGTCGCCGACCTGAAGGACTCCAGGCCGGGCAAGCCGGTGTTCAACCGTACCGTCACCCTGCGTGACTCCTGGGGACAGGGCTGA
Protein Properties
Protein Residues: 556
Protein Molecular Weight: 62.9 kDa
Protein Theoretical pI: 5.64
Hydropathicity (GRAVY score): -0.554
Charge at pH 7 (predicted): -12.45
Protein Sequence: 
>PA1794
MSKPETTAAPNFLRQIVQADLDAGKHAKIVTRFPPEPNGYLHIGHAKSICLNFGLAQEFAGDCHLRFDDTNPAKEDQEYIDAIEADIKWLGFQWSGEVCYASNYFDQLHAWAVELIKAGKAFVCDLGPEEMREYRGTLTEPGRNSPYRDRSVEENLDLFARMKAGEFPDGARSLRAKIDMGSPNMNLRDPILYRIRHAHHHQTGDKWCIYPSYDFTHGQSDAIEGITHSICTLEFEDHRPLYEWFLANLPVPAQPRQYEFSRLNLNYTVTSKRKLKQLVDEGHVSGWDDPRMSTLSGYRRRGYTPESIRNFCEMIGVNRASGVVDIGMLEFSIRDHLDATAPRAMCVLKPLKVVITNYPEGQVENLELPRHPKEDMGVRVLPFGRELFIDAGDFEEVPPAGYKRLIPGGEVRLRGSYVIRADEAIKDADGNIVELRCSYDPDTLGKNPEGRKVKGVIHWVPAEGSVECEVRLYDRLFRSANPEKAEEGGSFLDNINADSLQVLAGCRAEPSLGQANPEDRFQFEREGYFVADLKDSRPGKPVFNRTVTLRDSWGQG
References
External Links:
Resource Link
Genome ID: PA1794
Entrez Gene ID: 878828
NCBI Protein ID: 15596991
General Reference: PaperBLAST - Find papers about PA1794 and its homologs