Identification
Name: ATP synthase subunit c
Synonyms:
  • ATP synthase F(0) sector subunit c
  • Dicyclohexylcarbodiimide-binding protein
  • F-type ATPase subunit c
  • F-ATPase subunit c
  • Lipid-binding protein
Gene Name: atpE
Enzyme Class: Not Available
Biological Properties
General Function: Involved in hydrogen ion transmembrane transporter activity
Specific Function: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of 10 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
  • Oxidative phosphorylation PW000919
  • adenosine ribonucleotides de novo biosynthesis PWY-7219
  • superpathway of adenosine nucleotides de novo biosynthesis I PWY-7229
  • superpathway of purine nucleotides de novo biosynthesis I PWY-841
  • superpathway of adenosine nucleotides de novo biosynthesis II PWY-6126
    KEGG Reactions: Not Available
    SMPDB Reactions:
    Adenosine diphosphate+Thumb+4 Thumb+ThumbThumb+3 Thumb+Thumb
    PseudoCyc/BioCyc Reactions:
    Adenosine diphosphate+Thumb+4 Thumb+ThumbThumb+3 Thumb+Thumb
    Thumb
    ATP + H+[cytosol] + H2O ↔ ADP + phosphate + H+[periplasm]
    ReactionCard
    PAMDB001633+PAMDB110477+PAMDB000142PAMDB001633+PAMDB110479+PAMDB110244
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB000148Adenosine triphosphateMetaboCard
    PAMDB000345ADPMetaboCard
    PAMDB001633Hydrogen ionMetaboCard
    PAMDB000383PhosphateMetaboCard
    PAMDB000142WaterMetaboCard
    GO Classification:
    Component
    macromolecular complex
    protein complex
    proton-transporting ATP synthase complex, coupling factor F(o)
    proton-transporting two-sector ATPase complex, proton-transporting domain
    Function
    cation transmembrane transporter activity
    hydrogen ion transmembrane transporter activity
    inorganic cation transmembrane transporter activity
    ion transmembrane transporter activity
    monovalent inorganic cation transmembrane transporter activity
    substrate-specific transmembrane transporter activity
    transmembrane transporter activity
    transporter activity
    Process
    ATP biosynthetic process
    ATP synthesis coupled proton transport
    cellular nitrogen compound metabolic process
    metabolic process
    nitrogen compound metabolic process
    nucleobase, nucleoside and nucleotide metabolic process
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
    nucleoside phosphate metabolic process
    nucleotide metabolic process
    purine nucleoside triphosphate biosynthetic process
    purine nucleotide biosynthetic process
    purine nucleotide metabolic process
    purine ribonucleoside triphosphate biosynthetic process
    Gene Properties
    Locus tag: PA5559
    Strand: -
    Entrez Gene ID: 880088
    Accession: NP_254246.1
    GI: 15600752
    Sequence start: 6253235
    Sequence End: 6253492
    Sequence Length: 257
    Gene Sequence:
    >PA5559
    ATGGAAACTGTAGTTGGACTGACTGCTATCGCCGTTGCTCTGCTGATTGGCCTGGGTGCCCTGGGTACCGCCATCGGTTTCGGTCTGCTGGGTGGCAAGTTCCTGGAAGGCGCAGCTCGTCAGCCTGAAATGGTTCCGATGCTGCAGGTGAAAATGTTCATCGTCGCCGGCCTGCTGGACGCCGTGACCATGATCGGTGTGGGTATCGCCCTGTTCTTCACCTTCGCGAATCCCTTCGTTGGTCAAATCGCCGGCTAA
    Protein Properties
    Protein Residues: 85
    Protein Molecular Weight: 8.6 kDa
    Protein Theoretical pI: 4.59
    Hydropathicity (GRAVY score): 1.311
    Charge at pH 7 (predicted): -1.02
    Protein Sequence:
    >PA5559
    METVVGLTAIAVALLIGLGALGTAIGFGLLGGKFLEGAARQPEMVPMLQVKMFIVAGLLDAVTMIGVGIALFFTFANPFVGQIAG
    References
    External Links:
    Resource Link
    Genome ID: PA5559
    Entrez Gene ID: 880088
    NCBI Protein ID: 15600752
    General Reference: PaperBLAST - Find papers about PA5559 and its homologs