Identification
Name: Bifunctional protein hldE
Synonyms:
  • D-beta-D-heptose 7-phosphate kinase
  • D-beta-D-heptose 7-phosphotransferase
  • D-beta-D-heptose 1-phosphate adenosyltransferase
Gene Name: hldE
Enzyme Class:
Biological Properties
General Function: Involved in phosphotransferase activity, alcohol group as acceptor
Specific Function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
Thumb+D-glycero-beta-D-manno-Heptose 7-phosphate+ThumbThumb+Thumb
SMPDB Reactions:
Thumb+ThumbThumb+Thumb+Thumb
D-glycero-beta-D-manno-heptose 1-phosphate+Thumb+ThumbThumb+Thumb
PseudoCyc/BioCyc Reactions:
Thumb+ThumbThumb+Thumb+Thumb
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB000960ADP-D-Glycero-D-manno-heptoseMetaboCard
PAMDB003428D-glycero-beta-D-manno-heptose 7-phosphateMetaboCard
PAMDB001607D-Glycero-D-manno-heptose 1,7-bisphosphateMetaboCard
PAMDB001608D-Glycero-D-manno-heptose 1-phosphateMetaboCard
PAMDB001609D-Glycero-D-manno-heptose 7-phosphateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000633PyrophosphateMetaboCard
GO Classification:
Function
catalytic activity
nucleotidyltransferase activity
phosphotransferase activity, alcohol group as acceptor
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
biosynthetic process
carbohydrate metabolic process
metabolic process
primary metabolic process
Gene Properties
Locus tag: PA4996
Strand: -
Entrez Gene ID: 881680
Accession: NP_253683.1
GI: 15600189
Sequence start: 5612268
Sequence End: 5613692
Sequence Length: 1424
Gene Sequence:
>PA4996
ATGAAGTTGTCCATGCCCCGTTTCGACCAGGCCCCGGTGTTGGTGGTCGGTGATGTGATGCTCGACCGCTACTGGCATGGCGCGACTTCGCGCATTTCGCCGGAGGCCCCGGTGCCGGTGGTCCGCGTCGAACAGCACGAGGACCGCCCCGGCGGCGCCGCCAACGTCGCGCTGAACATCGCCGCGCTGGGCGCGCAGGCCTTGCTGGTCGGCGTCACCGGCCGCGACGAGGCCGCCGACAGCCTGGCCAACAGCCTCAAGGCCGCTGGAGTGGACGCGCGCTTCCAGCGCATCGATAGCCAGCCGACCATCGTCAAGCTGCGGGTCATGAGTCGCCACCAGCAACTGCTGCGGGTCGACTTCGAGGAACCGTTCCGCACCGACGCGGCGGCCCTGGCCGTGGACGTCGAGTCGCTGCTGGCCAAGGTCAAGGTGCTGGTGCTGTCCGACTACGGCAAGGGCGCGCTACAGAACCACCAGGTGCTGATCCAGGCGGCGCGGGCGCGCAACATTCCGGTACTGGCCGATCCCAAGGGCAAGGACTTCGCCATCTATCGCGGCGCCAGCCTGATCACCCCGAACCTGTCCGAATTCGAGACCATCGTCGGCCGTTGCGCCGACGAAGCCGAACTGGTCGCCAAGGGCCAGGCGCTGATGAGCGAACTCGACCTCGGTGCCTTGCTGGTGACCCGCGGCGAGCATGGCATGACCCTGCTCCGCCATGGCCAGCCGGCCCTGCACCTGCCGGCGCGGGCGCGGGAAGTGTTCGACGTCACCGGTGCCGGCGATACGGTCATCTCCACCCTGGCCGCGGCGCTTGCCGCCGGCGAGGAGCTGCCTTCCGCGGTGGGTCTGGCCAACCTGGCCGCCGGCATCGTGGTCGGCAAGCTGGGTACCGCGGCGATCAGCGCGCCCGAACTGCGTCGCGCGGTGCAGCGCGAGCAGGGTTCCGAGCGTGGCGTGCTGGGCCTGGAGCAATTGCTGCTGGCAATCGAAGACGCCCGCGCCCACGGCGAGAAGATCGTCTTCACCAATGGCTGCTTCGACATCCTTCACGCCGGCCACGTGACCTACCTCGAACAGGCGCGCGCCCAGGGCGACCGCCTGATCGTCGGGGTCAACGACGACGCCTCGGTCACTCGCCTGAAGGGCGTTGGCCGGCCGATCAACTCGGTGGACCGGCGCATGGCGGTACTCGCCGGGCTCGGCGCGGTGGACTGGGTGGTGAGCTTCGCCGAAGACACTCCTGAGCGCCTGCTCGAGCAGGTGCGTCCGGACGTGCTGGTCAAGGGCGGCGATTACGGCGTCGAGCAGGTGGTCGGCGCGCAGATCGTCAAGGCCTACGGCGGCGAGGTACGGGTGCTCGGCCTGGTGGAGAACAGCTCCACCACCGCCATCGTCGAGAAGATCCGCCAGAAAGGCTGA
Protein Properties
Protein Residues: 474
Protein Molecular Weight: 50.3 kDa
Protein Theoretical pI: 6.2
Hydropathicity (GRAVY score): 0.082
Charge at pH 7 (predicted): -4.63
Protein Sequence:
>PA4996
MKLSMPRFDQAPVLVVGDVMLDRYWHGATSRISPEAPVPVVRVEQHEDRPGGAANVALNIAALGAQALLVGVTGRDEAADSLANSLKAAGVDARFQRIDSQPTIVKLRVMSRHQQLLRVDFEEPFRTDAAALAVDVESLLAKVKVLVLSDYGKGALQNHQVLIQAARARNIPVLADPKGKDFAIYRGASLITPNLSEFETIVGRCADEAELVAKGQALMSELDLGALLVTRGEHGMTLLRHGQPALHLPARAREVFDVTGAGDTVISTLAAALAAGEELPSAVGLANLAAGIVVGKLGTAAISAPELRRAVQREQGSERGVLGLEQLLLAIEDARAHGEKIVFTNGCFDILHAGHVTYLEQARAQGDRLIVGVNDDASVTRLKGVGRPINSVDRRMAVLAGLGAVDWVVSFAEDTPERLLEQVRPDVLVKGGDYGVEQVVGAQIVKAYGGEVRVLGLVENSSTTAIVEKIRQKG
References
External Links:
Resource Link
Genome ID: PA4996
Entrez Gene ID: 881680
NCBI Protein ID: 15600189
General Reference: PaperBLAST - Find papers about PA4996 and its homologs