Formate dehydrogenase, nitrate-inducible, cytochrome b556(fdn) subunit (PA4810)

Identification
Name: Formate dehydrogenase, nitrate-inducible, cytochrome b556(fdn) subunit
Synonyms:
  • Anaerobic formate dehydrogenase cytochrome b556 subunit
  • Formate dehydrogenase-N subunit gamma
  • FDH-N subunit gamma
Gene Name: fdnI
Enzyme Class: Not Available
Biological Properties
General Function: Involved in respiratory electron transport chain
Specific Function: Formate dehydrogenase allows E.coli to use formate as major electron donor during anaerobic respiration, when nitrate is used as electron acceptor. Subunit gamma is the cytochrome b556(FDN) component of the formate dehydrogenase
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Formic acid + NAD ↔ Hydrogen ion + Carbon dioxide + NADH
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Formic acid + NAD ↔ Hydrogen ion + Carbon dioxide + NADH
ReactionCard
Thumb
formate[inner membrane] + NAD+[inner membrane] → CO2[inner membrane] + NADH[inner membrane] + H+[inner membrane]
ReactionCard
PAMDB110760+ETR-Quinones+PAMDB001633 → PAMDB000568+ETR-Quinols
formate + ETR-Quinones + Hydrogen ion → Carbon dioxide + ETR-Quinols
ReactionCard
Complex Reactions:
2 Thumb+Menaquinone 8+Thumb → Thumb+Thumb+Thumb
2 Hydrogen ion + Menaquinone 8 + Formic acid → Menaquinol 8 + Carbon dioxide + Hydrogen ion
ReactionCard
2 Thumb+Thumb+Thumb → Thumb+Thumb+Thumb
2 Hydrogen ion + Ubiquinone-8 + Formic acid → Ubiquinol-8 + Carbon dioxide + Hydrogen ion
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000568Carbon dioxideMetaboCard
PAMDB000053Formic acidMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001653Menaquinol 8MetaboCard
PAMDB000197NADMetaboCard
PAMDB000398NADHMetaboCard
PAMDB000237Ubiquinol-8MetaboCard
PAMDB001700Ubiquinone-8MetaboCard
GO Classification:
Component
cell part
formate dehydrogenase complex
integral to membrane
intrinsic to membrane
macromolecular complex
membrane
membrane part
protein complex
Function
catalytic activity
electron carrier activity
formate dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Process
cellular metabolic process
cellular respiration
electron transport chain
energy derivation by oxidation of organic compounds
generation of precursor metabolites and energy
metabolic process
respiratory electron transport chain
Gene Properties
Locus tag: PA4810
Strand: -
Entrez Gene ID: 880192
Accession: NP_253498.1
GI: 15600004
Sequence start: 5396992
Sequence End: 5397618
Sequence Length: 626
Gene Sequence: 
>PA4810
ATGAAAAATGAAATCCAGCGCTACAACGCCAACGAGCGCAGCAACCACTGGGCCGTGGCGATCCTGTTCTTCATGGCCGGGCTGTCCGGGCTGGCGCTGTTCCACCCGGCGCTGTTCTGGCTGACCAACCTGTTCGGCGGCGGTCCCTGGACGCGTATCCTGCACCCCTTCCTGGGGCTGGCGATGTTCGTCTTCTTCCTCGGCCTGGTGGTGCGCTTCGCCCACCACAACCGGGTGCAGAAGAGCGATATCCAGTGGCTCAAGCAGTGGCGCGACGTGGTCAGCAACCGCGAGGAGAACCTCCCGGAAGTCGGCCGCTACAACGCCGGGCAGAAGCTGCTGTTCTGGGTGCTGCTGCTGAGCATGCTGACCCTGCTGGTCACCGGCATCGTGATCTGGCGCCAGTACTTCAGTGCCTGGTTCGGCATCGAGGCGATCCGCCTGTCGGCGCTCCTGCACGCCTTCGCCGCCTTCGTCCTGATCGCCAGCATCATCGTGCACATCTACGCCGGCATCTGGGTCAAGGGCTCGATGGGCGCGATGCTCTACGGCAAGGTCAGCCGCGCCTGGGCGCGCAAGCACCATAACGGCTGGCTGAAGGAAGTCGGCAAGGGCGAGGAGCACTGA
Protein Properties
Protein Residues: 208
Protein Molecular Weight: 23.9 kDa
Protein Theoretical pI: 10.81
Hydropathicity (GRAVY score): 0.313
Charge at pH 7 (predicted): 12.39
Protein Sequence: 
>PA4810
MKNEIQRYNANERSNHWAVAILFFMAGLSGLALFHPALFWLTNLFGGGPWTRILHPFLGLAMFVFFLGLVVRFAHHNRVQKSDIQWLKQWRDVVSNREENLPEVGRYNAGQKLLFWVLLLSMLTLLVTGIVIWRQYFSAWFGIEAIRLSALLHAFAAFVLIASIIVHIYAGIWVKGSMGAMLYGKVSRAWARKHHNGWLKEVGKGEEH
References
External Links:
Resource Link
Genome ID: PA4810
Entrez Gene ID: 880192
NCBI Protein ID: 15600004
General Reference: PaperBLAST - Find papers about PA4810 and its homologs