Arsenical pump membrane protein (PA2278)

Identification
Name: Arsenical pump membrane protein
Synonyms:
  • Arsenic efflux pump protein
Gene Name: arsB
Enzyme Class: Not Available
Biological Properties
General Function: Involved in arsenite transmembrane transporter activity
Specific Function: Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Thumb
    Arsenite + Adenosine triphosphate + Water → ADP + Hydrogen ion + Phosphate + Arsenite
    ReactionCard
    Complex Reactions:
    Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Thumb
    Arsenite + Adenosine triphosphate + Water → ADP + Hydrogen ion + Phosphate + Arsenite
    ReactionCard
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB000148Adenosine triphosphateMetaboCard
    PAMDB000345ADPMetaboCard
    PAMDB001712ArseniteMetaboCard
    PAMDB001633Hydrogen ionMetaboCard
    PAMDB000383PhosphateMetaboCard
    PAMDB000142WaterMetaboCard
    GO Classification:
    Component
    cell part
    integral to membrane
    intrinsic to membrane
    membrane part
    Function
    anion transmembrane transporter activity
    arsenite transmembrane transporter activity
    inorganic anion transmembrane transporter activity
    ion transmembrane transporter activity
    substrate-specific transmembrane transporter activity
    transmembrane transporter activity
    transporter activity
    Gene Properties
    Locus tag: PA2278
    Strand: +
    Entrez Gene ID: 878634
    Accession: NP_250968.1
    GI: 15597474
    Sequence start: 2506978
    Sequence End: 2508261
    Sequence Length: 1283
    Gene Sequence: 
    >PA2278
ATGCTGATCGCCTTCGCCATCTTCCTGTTCACCCTGGTCCTGGTCATCTGGCAGCCCAGGGGCCTCGGCATCGGCTGGAGCGCCAGCATCGGTGCCCTGCTCGCCCTGGCGCTGGGCAGCGTCGCGCCGGGCGACATCCCGACCGTCTGGAACATCGTCTGGAATGCCACCGCCACCTTCATCGCGGTGATCGTCATCAGCCTGCTGCTGGACGAGGCCGGCTTCTTCGAATGGGCCGCGCTGCACGTCGCGCGCTGGGCTGGCGGCGACGGCCGGCGCCTGTTCGCCTTCTGCGTGCTGCTCGGCGCGGCGGTCTCGGCGCTGTTCGCCAACGACGGCGCGGCGCTGATCCTCACGCCCATCGTGATGTCGATGCTGCTGGCCCTGCGCTTCAGCCCGGCGGCGACCCTGGCCTTCGTCATGGCGGCGGGCTTCATCGCCGACAGCGCCAGCCTGCCGCTGGTGGTCTCGAACCTGGTGAACATCGTCTCGGCCGACTACTTCGGGCTCGGCTTCGGCGAGTACGCCGCGGTCATGCTGCCGGTAAACCTGGTGAGCGTCGCGACCTCCCTGCTGGTGCTGTTCCTCTATTTCCGCCGCGACCTGCCGCCGGTCTATGCGCTGGAGCAATTGAAGCCGCCGCGGGCGGCGATCCGCGACCGCGCGACCTTCGTCGTCGGTGGCTGGATGCTGCTGGTCCTGCTCGCCGGGCTGTTCGCCCTGGAGCCGCTGGGCGTCCCCGTCAGCGCGGTGGCCGCGGCCTGTGCGGCGCTGCTGCTGGCGGTGGCCGGGCGCGGGCGGGTGATCTCGACCCGGCGGGTGCTGCGCGAAGCGCCCTGGCAGATCGTGGTCTTCTCGCTGGGCATGTACCTGGTGGTCTACGGCCTGAAGAACGCCGGTCTCACCGACCTCCTGGCGCAGCTCCTGAACCGCCTGGCCGAGCACGGCGTATGGGCGGCCGCGCTGGGTACCGGACTGCTTTCCGCCGCCCTCTCGTCGGTAATGAACAACATGCCCAGCATGCTGCTCGGCGCCCTGTCGATCCAGGCCAGCGACACCGCCGGCGCGGTGCGCGAAGCGATGATCTACGCCAACGTCATCGGCTGCGACCTGGGTCCGAAGATCACCCCTATCGGCAGCCTGGCGACGCTGCTCTGGCTGCACGTGCTGGCGCGCAAAGGCATGCGCATCACCTGGGGCTACTACTTCAGGGTCGGCGCCCTGCTGACCCTGCCGGTCCTGCTGGCGACCCTTTCGGCCCTGGCCCTGCGCCTGGCCATCTGA
    Protein Properties
    Protein Residues: 427
    Protein Molecular Weight: 45.1 kDa
    Protein Theoretical pI: 9.58
    Hydropathicity (GRAVY score): 1.066
    Charge at pH 7 (predicted): 6.62
    Protein Sequence: 
    >PA2278
MLIAFAIFLFTLVLVIWQPRGLGIGWSASIGALLALALGSVAPGDIPTVWNIVWNATATFIAVIVISLLLDEAGFFEWAALHVARWAGGDGRRLFAFCVLLGAAVSALFANDGAALILTPIVMSMLLALRFSPAATLAFVMAAGFIADSASLPLVVSNLVNIVSADYFGLGFGEYAAVMLPVNLVSVATSLLVLFLYFRRDLPPVYALEQLKPPRAAIRDRATFVVGGWMLLVLLAGLFALEPLGVPVSAVAAACAALLLAVAGRGRVISTRRVLREAPWQIVVFSLGMYLVVYGLKNAGLTDLLAQLLNRLAEHGVWAAALGTGLLSAALSSVMNNMPSMLLGALSIQASDTAGAVREAMIYANVIGCDLGPKITPIGSLATLLWLHVLARKGMRITWGYYFRVGALLTLPVLLATLSALALRLAI
    References
    External Links:
    Resource Link
    Genome ID: PA2278
    Entrez Gene ID: 878634
    NCBI Protein ID: 15597474
    General Reference: PaperBLAST - Find papers about PA2278 and its homologs