Record Information
Version 1.0
Update Date 1/22/2018 12:54:54 PM
Metabolite IDPAMDB001712
Identification
Name: Arsenite
Description:Arsenite is a chemical compound containing an arsenic oxoanion where arsenic has oxidation state +3.; In chemistry an arsenite is a chemical compound containing an arsenic oxoanion where arsenic has oxidation state +3. Examples of arsenites include sodium arsenite which contains a polymeric linear anion, [AsO2−]n, silver arsenite, Ag3AsO3, which contains the trigonal, [AsO3]3− anion, sometimes called ortho-arsenite. Arsenite contrasts to the corresponding anions of the lighter members of group 15, phosphite which has the structure [HPO3]2− and nitrite, NO2− which is planar. Sodium arsenite is used in the water gas shift reaction to remove carbon dioxide.
Structure
Thumb
Synonyms:
  • AArsenite (AsO33-)
  • Arsenic (III) oxide
  • Arsenic (III) trioxide
  • Arsenic oxide
  • Arsenic sesquioxide
  • Arsenic trioxide
  • Arsenicum album
  • Arsenious oxide
  • Arsenite
  • Arsenite(3-)
  • Arsenolite
  • Arsenous acid anhydride
  • Arsenous acid ion(3-)
  • Arsenous anhydride
  • Arsenous oxide
  • Arsenous oxide anhydride
  • Arsenous trioxide
  • Arsodent
  • Arsorite
  • As(OH)3
  • As(OH)3
  • AsO33
  • Claudelite
  • Clauditite
  • Crude arsenic
  • Diarsenic oxide
  • Diarsenic trioxide
  • Diarsonic trioxide
  • Trioxidoarsenate(3)
  • Trioxidoarsenate(3-)
  • Trioxidoarsenic acid(3)
  • Trioxidoarsenic acid(3-)
  • Trioxoarsenate(3)
  • Trioxoarsenate(3-)
  • Trioxoarsenate(III)
  • Trioxoarsenic acid(3)
  • Trioxoarsenic acid(3-)
  • Trioxoarsenic acid(iii)
  • Trisoxylatoarsine
  • White arsenic
  • [AsO3]3
Chemical Formula: AsH3O3
Average Molecular Weight: 125.9436
Monoisotopic Molecular Weight: 125.929815379
InChI Key: GCPXMJHSNVMWNM-UHFFFAOYSA-N
InChI:InChI=1S/AsH3O3/c2-1(3)4/h2-4H
CAS number: 15502-74-6
IUPAC Name:arsorous acid
Traditional IUPAC Name: arsenite
SMILES:O[As](O)O
Chemical Taxonomy
Taxonomy DescriptionThis compound belongs to the class of inorganic compounds known as miscellaneous arsenites. These are inorganic compounds in which the largest metallic oxoanion is arsenite, to which either no atom or a non metal atom is bonded.
Kingdom Inorganic compounds
Super ClassMixed metal/non-metal compounds
Class Miscellaneous mixed metal/non-metals
Sub ClassMiscellaneous metallic oxoanionic compounds
Direct Parent Miscellaneous arsenites
Alternative Parents
Substituents
  • Arsenite
  • Trivalent inorganic arsenic compound
  • Inorganic metalloid salt
  • Inorganic arsenic compound
  • Acyclic compound
Molecular Framework Acyclic compounds
External Descriptors
Physical Properties
State: Solid
Charge:-1
Melting point: Boiling Pt : 465 °C
Experimental Properties:
PropertyValueSource
Predicted Properties
PropertyValueSource
logP-0.86ChemAxon
pKa (Strongest Acidic)6.84ChemAxon
pKa (Strongest Basic)-6.2ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area60.69 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity7.69 m3·mol-1ChemAxon
Polarizability6.27 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Biological Properties
Cellular Locations: Cytoplasm
Reactions:
Pathways: Not Available
Spectra
Spectra:
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-004i-0900000000-26c04713335c396980e7View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-004i-0900000000-982efae6163f8706efe3View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-004i-1900000000-1ccde29b5404c5ce889bView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-00di-0900000000-362cd1f7701cf877d421View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-00di-1900000000-2bdaffd6d6a5f68f6df3View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-00di-0900000000-734f18bf77d9e82629a2View in MoNA
References
References: Not Available
Synthesis Reference: Not Available
Material Safety Data Sheet (MSDS) Not Available
External Links:
ResourceLink
CHEBI ID29866
HMDB IDHMDB11620
Pubchem Compound ID544
Kegg IDC06697
ChemSpider ID529
WikipediaArsenite
BioCyc IDCPD-763
EcoCyc IDCPD-763
Ligand ExpoTAS

Enzymes

General function:
Involved in arsenate reductase (glutaredoxin) activity
Specific function:
Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance
Gene Name:
arsC
Locus Tag:
PA2279
Molecular weight:
16.6 kDa
Reactions
Arsenate + glutaredoxin = arsenite + glutaredoxin disulfide + H(2)O.
General function:
Involved in arsenite transmembrane transporter activity
Specific function:
Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Gene Name:
arsB
Locus Tag:
PA2278
Molecular weight:
45.1 kDa

Transporters