Cytochrome c biogenesis ATP-binding export protein CcmA (PA1475)

Identification
Name: Cytochrome c biogenesis ATP-binding export protein CcmA
Synonyms:
  • Heme exporter protein A
Gene Name: ccmA
Enzyme Class:
Biological Properties
General Function: Involved in nucleotide binding
Specific Function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system
Cellular Location: Cell inner membrane; Peripheral membrane protein
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Thumb
Adenosine triphosphate + Water + Heme → ADP + Hydrogen ion + Phosphate + Heme
ReactionCard
Complex Reactions:
Thumb+Thumb+heme(In) → Thumb+Thumb+heme(Out)
Adenosine triphosphate + Water + heme(In) → ADP + Inorganic phosphate + heme(Out)
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB000481HemeMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001776Inorganic phosphateMetaboCard
PAMDB000383PhosphateMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Component
cell part
outer membrane-bounded periplasmic space
periplasmic space
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
ATPase activity
binding
catalytic activity
hydrolase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
nucleoside binding
nucleoside-triphosphatase activity
nucleotide binding
purine nucleoside binding
pyrophosphatase activity
transporter activity
Process
cellular component assembly
cellular component organization
cellular component organization or biogenesis
cellular protein complex assembly
cytochrome complex assembly
macromolecular complex assembly
protein complex assembly
Gene Properties
Locus tag: PA1475
Strand: +
Entrez Gene ID: 880978
Accession: NP_250166.1
GI: 15596672
Sequence start: 1602179
Sequence End: 1602880
Sequence Length: 701
Gene Sequence: 
>PA1475
ATGTCCGATCCTGCTGAAGTCCCCACAGCCAGCCCCTTGCTGGAAACCGTCGGGCTCGCCTGCGAGCGCGACTGGCGCATGCTGTTCGAGCGCCTCGACCTGCGCCTGGCCGCCGGCGAGATGTTGCAGGTGGTGGGTCCCAACGGCAGCGGCAAGACCAGCCTGCTGCGCCTGCTGTCCGGACTGATGCAGCCGACCGCCGGGGAAGTCCGCCTGAACGGCCGGCCGCTCGCCGAACAGCGCGGCGAACTGGCCCGCAGCCTGTTGTGGATCGGCCACGCCGCGGGAATCAAGGGCCTGCTCAGCGCCGAGGAGAACCTCACCTGGCTCTGCGCGCTGCACCAGCCGGCCAGCCGCGAGGCGATCTGGCAGGCCCTGGCCGACGTCGGCCTGCGTGGCTTCGAGGACGTTCCCTGTCACACCCTTTCCGCCGGCCAGCAACGCCGCGTGGCGCTGGCCCGCCTGTACCTGGACGCACCGCCCTTGTGGATCCTCGATGAACCCTTCACCGCCCTCGACAAACAGGGGGTGGCGCAACTGGAAACGCACCTGGCCGGGCATTGCCAGCGCGGCGGGATGGTGGTGCTGACCACCCACCACAGCCTGCAGCAGGTGCCCGCCGGCTACCGCGAGCTGGACCTTGGTGCGCTCAAGGCGGCCAGCGGCGCGACGGTCGAGCCGGCGCTGGGCGACCCGGCATGA
Protein Properties
Protein Residues: 233
Protein Molecular Weight: 25 kDa
Protein Theoretical pI: 5.88
Hydropathicity (GRAVY score): -0.009
Charge at pH 7 (predicted): -4.44
Protein Sequence: 
>PA1475
MSDPAEVPTASPLLETVGLACERDWRMLFERLDLRLAAGEMLQVVGPNGSGKTSLLRLLSGLMQPTAGEVRLNGRPLAEQRGELARSLLWIGHAAGIKGLLSAEENLTWLCALHQPASREAIWQALADVGLRGFEDVPCHTLSAGQQRRVALARLYLDAPPLWILDEPFTALDKQGVAQLETHLAGHCQRGGMVVLTTHHSLQQVPAGYRELDLGALKAASGATVEPALGDPA
References
External Links:
Resource Link
Genome ID: PA1475
Entrez Gene ID: 880978
NCBI Protein ID: 15596672
General Reference: PaperBLAST - Find papers about PA1475 and its homologs