Pseudomonas aeruginosa heme oxygenase (PA0672)

Identification
Name: Pseudomonas aeruginosa heme oxygenase
Synonyms:
  • PaHO
Gene Name: hemO
Enzyme Class:

EC 1.14.14.18

Biological Properties
General Function: heme oxidation, oxidation-reduction process
Specific Function: heme oxygenase (decyclizing) activity
Cellular Location: Unknown
KEGG Pathways:

Metabolic pathways:00860

KEGG Reactions:
Thumb + Thumb → Thumb + thumb + thumb + thumb

Heme b + O2 → Beta biliverdin + Delta biliverdin + CO + Fe
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
PAMDB110426+PAMDB000624+Donor-H2+PAMDB001633 → PAMDB120516+FE+2+PAMDB003394+Acceptor+PAMDB000142
ferroheme b + Oxygen + Donor-H2 + Hydrogen ion → biliverdin-IX-α + FE+2 + CO + Acceptor + Water
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB ID Name View
PAMDB000172 Ferrous Iron MetaboCard
PAMDB000624 Oxygen MetaboCard
PAMDB003394 Carbon Monoxide MetaboCard
PAMDB000481 Heme b MetaboCard
PAMDB100089 Beta Biliverdin MetaboCard
PAMDB100090 Delta Biliverdin MetaboCard
GO Classification:
Function
heme oxygenase (decyclizing) activity
Process
heme oxidation
oxidation-reduction process
Gene Properties
Locus tag: PA0672
Strand: +
Entrez Gene ID: 880820
Accession: NP_249363.1
GI: 5595869
Sequence start: 732959
Sequence End: 733555
Sequence Length: 597
Gene Sequence: 
>PA0672
ATGGATACCCTGGCCCCTGAATCCACTCGGCAAAACCTGCGTTCGCAACGCCTCAACCTGCTGACCAACGAGCCGCACCAGCGCCTGGAGAGCCTGGTGA AGAGCAAGGAACCCTTCGCCAGCCGGGACAATTTCGCCCGCTTCGTCGCCGCCCAGTACCTCTTCCAGCATGACCTGGAGCCGCTTTATCGCAACGAAGC GCTGGCCCGCCTGTTCCCCGGCCTGGCTTCCCGCGCCCGCGACGACGCCGCTCGTGCAGACCTGGCGGACCTCGGCCATCCGGTACCGGAGGGCGACCAG AGCGTGCGCGAGGCCGACCTGAGCCTGGCCGAGGCACTGGGCTGGCTGTTCGTTTCCGAAGGTTCGAAGCTGGGCGCTGCGTTCCTGTTCAAGAAAGCCG CCGCGCTCGAACTCGACGAGAACTTCGGCGCCCGCCATCTGGCCGAGCCGGAAGGCGGCCGCGCGCAAGGCTGGAAGAGCTTCGTGGCGATCCTCGACGG CATCGAGCTGAACGAGGAGGAAGAGCGCCTGGCCGCCAAGGGCGCCAGCGATGCCTTCAATCGTTTCGGCGACCTGCTGGAGCGTACCTTCGCCTGA
Protein Properties
Protein Residues: 198
Protein Molecular Weight: 22 kDa
Protein Theoretical pI: 4.78
Hydropathicity (GRAVY score): -0.418
Charge at pH 7 (predicted): -8.03
Protein Sequence: 
>PA0672
MDTLAPESTRQNLRSQRLNLLTNEPHQRLESLVKSKEPFASRDNFARFVAAQYLFQHDLEPLYRNEALARLFPGLASRARDDAARADLADLGHPVPEGDQ SVREADLSLAEALGWLFVSEGSKLGAAFLFKKAAALELDENFGARHLAEPEGGRAQGWKSFVAILDGIELNEEEERLAAKGASDAFNRFGDLLERTFA
References
External Links:
Resource Link
Genome ID: PA0672
Entrez Gene ID: 880820
NCBI Protein ID: 5595869
General Reference: PaperBLAST - Find papers about PA0672 and its homologs