Undecaprenyl diphosphate (PAMDB000394)

General function:

Involved in catalytic activity

Specific function:

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

Gene Name:

mrcB

Locus Tag:

PA4700

Molecular weight:

85.5 kDa

Reactions

General function:

Involved in penicillin binding

Specific function:

Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates

Gene Name:

ftsI

Locus Tag:

PA4418

Molecular weight:

62.9 kDa

Reactions

General function:

Involved in transferase activity, transferring alkyl or aryl (other than methyl) groups

Specific function:

Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide

Gene Name:

uppS

Locus Tag:

PA3652

Molecular weight:

28 kDa

Reactions

General function:

Involved in undecaprenyl-diphosphatase activity

Specific function:

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

Gene Name:

uppP

Locus Tag:

PA1959

Molecular weight:

30.7 kDa

Reactions

General function:

Involved in catalytic activity

Specific function:

Cell wall formation. The enzyme has a penicillin- insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase C-terminal domain which may not be functional

Gene Name:

pbpC

Locus Tag:

PA2272

Molecular weight:

61.1 kDa

General function:

Involved in lipid transporter activity

Specific function:

Specific function unknown

Gene Name:

mviN

Locus Tag:

PA4562

Molecular weight:

56.1 kDa