Undecaprenyl-diphosphatase (PA1959)

Identification
Name: Undecaprenyl-diphosphatase
Synonyms:
  • Bacitracin resistance protein
  • Undecaprenyl pyrophosphate phosphatase
Gene Name: uppP
Enzyme Class:
Biological Properties
General Function: Involved in undecaprenyl-diphosphatase activity
Specific Function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
KEGG Reactions:
di-trans,poly-cis-Undecaprenyl diphosphate+Thumb+Thumb ↔ Thumb+Thumb
di-trans,poly-cis-Undecaprenyl diphosphate + Water + Undecaprenyl diphosphate ↔ Di-trans,poly-cis-undecaprenyl phosphate + Phosphate
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+Thumb → Thumb+Thumb+Thumb
Undecaprenyl diphosphate + Water → Hydrogen ion + Di-trans,poly-cis-undecaprenyl phosphate + Phosphate
ReactionCard
Complex Reactions:
Thumb+Thumb → Thumb+Thumb+Thumb
Water + Undecaprenyl diphosphate → Hydrogen ion + Phosphate + Undecaprenyl phosphate
ReactionCard
Thumb+Thumb → Thumb+Thumb+Thumb
Water + Undecaprenyl diphosphate → Hydrogen ion + Phosphate + Undecaprenyl phosphate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB001145Di-trans,poly-cis-undecaprenyl phosphateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001776Inorganic phosphateMetaboCard
PAMDB000383PhosphateMetaboCard
PAMDB000394Undecaprenyl diphosphateMetaboCard
PAMDB001054Undecaprenyl phosphateMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Component
cell part
membrane
Function
catalytic activity
hydrolase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
undecaprenyl-diphosphatase activity
Process
cellular metabolic process
dephosphorylation
metabolic process
phosphate metabolic process
phosphorus metabolic process
Gene Properties
Locus tag: PA1959
Strand: +
Entrez Gene ID: 877690
Accession: NP_250649.1
GI: 15597155
Sequence start: 2143173
Sequence End: 2144006
Sequence Length: 833
Gene Sequence: 
>PA1959
ATGGAGTGGTGGACTGCTTTCCAGGCGTTCATCCTGGGCGTCGTGGAGGGGCTGACCGAGTTCCTGCCGATTTCCAGCACCGGGCACCAGATCATCGTCGCCGACCTCATCGGCTTCGGCGGCGAACGCGCCAAGGCGTTCAACATCATCATCCAACTGGCGGCGATCCTCGCTGTCGTCTGGGAATTTCGGGGAAAGATCTTTCAAGTCGTCCGTGACCTGCCGAGCCAGCGCCAGGCCCAGCGTTTCACCGCCAACCTGCTGATCGCGTTCTTCCCGGCGGTAGTCCTCGGCGTCCTGTTCGCCGACCTGATCCACGAGTGGCTGTTCAATCCGATCACCGTCGCCCTGGCGCTGGTGGTGGGCGGGGTGGTCATGCTCTGGGCCGAGCGCCGGAAGCATGTGATCCGCGCCGAACACGTCGACGACATGACCTGGAAGGACGCCCTGAAGATCGGCTGTGCCCAGTGCCTGGCGATGATCCCCGGCACCTCGCGGTCCGGCGCGACCATCATCGGCGGCCTGCTGTTCGGCCTTTCGCGCAAGGCGGCCACCGAGTTCTCGTTCTTCCTGGCGATGCCGACCATGGTCGGCGCGGCGGTCTATTCCGGATACGTGTACCGCGACCTGTTCCGCCCCGAGGACCTGCCGGTGTTCGCCGTCGGCTTCGTCACCTCGTTCGTCTTCGCCATGCTGGCGGTGCGTGCCTTGCTGAAGTTCATCGGCAACCACAGCTACGCGGCTTTCGCCTGGTATCGGATCGCCTTCGGCCTGCTGATCCTGGCGACCTGGCAATTCCACCTGATCGACTGGAGCACCGCCGGCGAGGTGTGA
Protein Properties
Protein Residues: 277
Protein Molecular Weight: 30.7 kDa
Protein Theoretical pI: 8.24
Hydropathicity (GRAVY score): 0.722
Charge at pH 7 (predicted): 2.37
Protein Sequence: 
>PA1959
MEWWTAFQAFILGVVEGLTEFLPISSTGHQIIVADLIGFGGERAKAFNIIIQLAAILAVVWEFRGKIFQVVRDLPSQRQAQRFTANLLIAFFPAVVLGVLFADLIHEWLFNPITVALALVVGGVVMLWAERRKHVIRAEHVDDMTWKDALKIGCAQCLAMIPGTSRSGATIIGGLLFGLSRKAATEFSFFLAMPTMVGAAVYSGYVYRDLFRPEDLPVFAVGFVTSFVFAMLAVRALLKFIGNHSYAAFAWYRIAFGLLILATWQFHLIDWSTAGEV
References
External Links:
Resource Link
Genome ID: PA1959
Entrez Gene ID: 877690
NCBI Protein ID: 15597155
General Reference: PaperBLAST - Find papers about PA1959 and its homologs