Identification
Name: Undecaprenyl pyrophosphate synthase
Synonyms:
  • UPP synthase
  • Di-trans,poly-cis-decaprenylcistransferase
  • Undecaprenyl diphosphate synthase
  • UDS
Gene Name: uppS
Enzyme Class:
Biological Properties
General Function: Involved in transferase activity, transferring alkyl or aryl (other than methyl) groups
Specific Function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+8 Thumbdi-trans,poly-cis-Undecaprenyl diphosphate+8 Thumb+Thumb
SMPDB Reactions:
Farnesyl pyrophosphate+8 Isopentenyl pyrophosphate+Thumb+8 Thumb8 Pyrophosphate+di-trans,octa-cis-undecaprenyl diphosphate
Farnesyl pyrophosphate + 8 Isopentenyl pyrophosphate + Farnesyl pyrophosphate + 8 Isopentenyl pyrophosphate → 8 Pyrophosphate + di-trans,octa-cis-undecaprenyl diphosphate
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+8 Thumb8 Thumb+Thumb
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000210Farnesyl pyrophosphateMetaboCard
PAMDB000348Isopentenyl pyrophosphateMetaboCard
PAMDB000633PyrophosphateMetaboCard
PAMDB000394Undecaprenyl diphosphateMetaboCard
GO Classification:
Function
catalytic activity
transferase activity
transferase activity, transferring alkyl or aryl (other than methyl) groups
Gene Properties
Locus tag: PA3652
Strand: -
Entrez Gene ID: 880553
Accession: NP_252342.1
GI: 15598848
Sequence start: 4090900
Sequence End: 4091655
Sequence Length: 755
Gene Sequence:
>PA3652
ATGGAAAAGACCCGGAAGGATGTGTGCGTGCCACGCCACGTGGCCATTATCATGGACGGTAACAATCGCTGGGCGAAGAAGCGTCTTCTGCCCGGCGTCGCCGGCCACAAGGCCGGTGTCGATGCCGTCAGGGCGGTGATCGAGGTCTGCGCCGAGGCAGGGGTCGAGGTCCTCACCCTGTTCGCGTTCTCCAGCGAGAACTGGCAGCGTCCGGCGGACGAAGTCAGCGCGCTGATGGAGCTGTTTCTCGTGGCCCTGCGCCGCGAGGTGCGCAAGCTCGACGAGAACGGCATCCGCCTGCGCATCATCGGCGATCGCACGCGTTTCCATCCGGAGTTGCAGGCGGCCATGCGCGAAGCGGAAGCCGCCACTGCCGGCAATACCCGTTTCCTCCTCCAGGTCGCCGCCAACTACGGCGGCCAGTGGGACATCGTCCAGGCCGCACAGCGCCTGGCGCGCGAGGTCCAGGGCGGGCACCTGGCGGCGGACGATATCTCCGCCGAGCTGCTCCAGGGCTGCCTGGTGACCGGCGACCAGCCGCTGCCCGACCTGTGCATCCGCACCGGCGGCGAGCATCGCATCAGCAATTTCCTTCTCTGGCAGCTGGCCTACGCCGAGCTGTATTTCTCCGACCTGTTCTGGCCCGACTTCAAGCACGCGGCGATGCGGGCTGCCCTGGCGGATTTCTCCAAGCGCCAGCGCCGCTTCGGCAAGACCAGCGAGCAAGTCGAGGCCGAGGCCCGTCCGTCATGCTGA
Protein Properties
Protein Residues: 251
Protein Molecular Weight: 28 kDa
Protein Theoretical pI: 7.51
Hydropathicity (GRAVY score): -0.199
Charge at pH 7 (predicted): 1.3
Protein Sequence:
>PA3652
MEKTRKDVCVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAGVEVLTLFAFSSENWQRPADEVSALMELFLVALRREVRKLDENGIRLRIIGDRTRFHPELQAAMREAEAATAGNTRFLLQVAANYGGQWDIVQAAQRLAREVQGGHLAADDISAELLQGCLVTGDQPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHAAMRAALADFSKRQRRFGKTSEQVEAEARPSC
References
External Links:
Resource Link
Genome ID: PA3652
Entrez Gene ID: 880553
NCBI Protein ID: 15598848
General Reference: PaperBLAST - Find papers about PA3652 and its homologs