Guanylate kinase (PA5336)

Identification
Name: Guanylate kinase
Synonyms:
  • GMP kinase
Gene Name: gmk
Enzyme Class:
Biological Properties
General Function: Involved in protein binding
Specific Function: Essential for recycling GMP and indirectly, cGMP
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + 2'-Deoxyguanosine 5'-monophosphate ↔ ADP + dGDP
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + Guanosine monophosphate ↔ ADP + Guanosine diphosphate
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + Guanosine monophosphate ↔ ADP + Guanosine diphosphate
ReactionCard
Thumb+Thumb ↔ Thumb+dGDP
Adenosine triphosphate + 2'-Deoxyguanosine 5'-monophosphate ↔ ADP + dGDP
ReactionCard
SMPDB Reactions:
Thumb+Thumb → Adenosine diphosphate+Thumb+Thumb
Guanosine monophosphate + Adenosine triphosphate → Adenosine diphosphate + Guanosine diphosphate + ADP
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + 2'-Deoxyguanosine 5'-monophosphate ↔ ADP + dGDP
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + Guanosine monophosphate ↔ ADP + Guanosine diphosphate
ReactionCard
Complex Reactions:
Thumb+Thumb → Thumb+Thumb
Adenosine triphosphate + Guanosine monophosphate → ADP + Guanosine diphosphate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0002312'-Deoxyguanosine 5'-monophosphateMetaboCard
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB000209dGDPMetaboCard
PAMDB000296Guanosine diphosphateMetaboCard
PAMDB000369Guanosine monophosphateMetaboCard
GO Classification:
Function
catalytic activity
guanylate kinase activity
phosphotransferase activity, phosphate group as acceptor
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
cellular nitrogen compound metabolic process
metabolic process
nitrogen compound metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleoside phosphate metabolic process
nucleotide metabolic process
purine nucleotide metabolic process
Gene Properties
Locus tag: PA5336
Strand: +
Entrez Gene ID: 878047
Accession: NP_254023.1
GI: 15600529
Sequence start: 6005199
Sequence End: 6005810
Sequence Length: 611
Gene Sequence: 
>PA5336
ATGTCCGGCACCCTGTACATCGTTTCCGCTCCCTCCGGCGCCGGCAAGACCAGCCTGGTGAAGGCCCTGCTCGACGCCGCCCCCGAGGTCCGCGTGTCCGTCTCCCATACCACCCGCGGCATGCGTCCGGGCGAGGTGGACGGGGTCAACTACCACTTCACCAGCCGCGAGGAATTCCTCGCCATGCTCGAGCGCAACGAGTTCCTCGAGCATGCCGAAGTCTTCGGCAACCTCTACGGCACCTCGCAGCGCTGGGTCGAGAAAACCCTCGCCGAAGGCCTCGACCTGATCCTCGAGATCGACTGGCAGGGCGCCCAGCAGGTGCGCCGGCTGATGCCCGAGGCCCAATCGATCTTCATCCTCCCGCCGAGCCAGGAAGCCCTGCGCCAGCGCCTGACCAACCGCGGCCAGGACAGCGACGAGGTGATCGAGCGGCGCATGCGCGAAGCCGTCAGCGAAATGAGCCACTACGTGGAGTACGATCACCTGGTGATCAACGACGATTTCGCCCACGCCCTGGACGACCTCAAGGCGATCTTCCGCGCCCGCCAGTTGCGCCAGGACGCCCAGCAGCAACGCCACGCCGAACTGCTCGGTCGTCTGCTCGCCTAA
Protein Properties
Protein Residues: 203
Protein Molecular Weight: 23.1 kDa
Protein Theoretical pI: 5.34
Hydropathicity (GRAVY score): -0.406
Charge at pH 7 (predicted): -6.31
Protein Sequence: 
>PA5336
MSGTLYIVSAPSGAGKTSLVKALLDAAPEVRVSVSHTTRGMRPGEVDGVNYHFTSREEFLAMLERNEFLEHAEVFGNLYGTSQRWVEKTLAEGLDLILEIDWQGAQQVRRLMPEAQSIFILPPSQEALRQRLTNRGQDSDEVIERRMREAVSEMSHYVEYDHLVINDDFAHALDDLKAIFRARQLRQDAQQQRHAELLGRLLA
References
External Links:
Resource Link
Genome ID: PA5336
Entrez Gene ID: 878047
NCBI Protein ID: 15600529
General Reference: PaperBLAST - Find papers about PA5336 and its homologs