Diaminopimelate decarboxylase (PA5277)

Identification
Name: Diaminopimelate decarboxylase
Synonyms:
  • DAP decarboxylase
Gene Name: lysA
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: Meso-2,6-diaminoheptanedioate = L-lysine + CO(2)
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb ↔ Thumb+Thumb
Meso-2,6-Diaminoheptanedioate ↔ L-Lysine + Carbon dioxide
ReactionCard
SMPDB Reactions:
Thumb+Thumb → L-Lysine+Thumb+Thumb
Meso-2,6-Diaminoheptanedioate + Hydrogen ion → L-Lysine + Carbon dioxide + L-Lysine
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb → Thumb+Thumb
Diaminopimelic acid + Hydrogen ion → Carbon dioxide + L-Lysine
ReactionCard
Thumb ↔ Thumb+Thumb
Meso-2,6-Diaminoheptanedioate ↔ L-Lysine + Carbon dioxide
ReactionCard
Thumb+Thumb → L-Lysine+Thumb+Thumb
Meso-2,6-Diaminoheptanedioate + Hydrogen ion → L-Lysine + Carbon dioxide + L-Lysine
ReactionCard
Thumb
meso-diaminopimelate + H+ → CO2 + L-lysine
ReactionCard
Complex Reactions:
Thumb+Thumb → Thumb+Thumb
Diaminopimelic acid + Hydrogen ion → Carbon dioxide + L-Lysine
ReactionCard
Thumb → Thumb+Thumb
Meso-2,6-Diaminoheptanedioate → L-Lysine + Carbon dioxide
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000568Carbon dioxideMetaboCard
PAMDB000360Diaminopimelic acidMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000075L-LysineMetaboCard
PAMDB002055Meso-2,6-DiaminoheptanedioateMetaboCard
GO Classification:
Function
carbon-carbon lyase activity
carboxy-lyase activity
catalytic activity
diaminopimelate decarboxylase activity
lyase activity
Process
aspartate family amino acid metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
cellular metabolic process
lysine biosynthetic process
lysine biosynthetic process via diaminopimelate
lysine metabolic process
metabolic process
Gene Properties
Locus tag: PA5277
Strand: +
Entrez Gene ID: 877749
Accession: NP_253964.1
GI: 15600470
Sequence start: 5941487
Sequence End: 5942734
Sequence Length: 1247
Gene Sequence: 
>PA5277
ATGGACACATTCAGTTACCGCGACGCTGAGCTGTTCGCGGAAGGGGTGGCGCTTTCCCGCATCGCCGAGCGTTTCGGCACGCCCACCTACGTCTATTCCCGCGCGCACATCGAGGCCCAGTACCGCGCCTATGCCGATGCCCTCGCCGGCATGCCGCATCTGGTCTGCTTCGCGGTCAAGGCCAACTCCAACCTCGGGGTGCTGAATGTGCTGGCGCGCCTCGGCGCCGGTTTCGACATCGTTTCCCGCGGTGAGCTGGAGCGTGTCCTGGCCGCCGGCGGCGATCCGGCCAAGGTGGTGTTCTCCGGCGTCGGCAAGACCCGCGACGACATGCGCCGCGCCCTGGAAGTCGGCGTGCACTGCTTCAACGTCGAGTCCGGCGAAGAGCTGGAGCGCCTGCAACGGGTAGCTGCGGAACTCGGCGTGAAAGCGCCGGTATCGCTGCGGGTCAACCCGGACGTGGACGCCCAGACCCACCCCTATATCTCCACCGGCCTGAAAGAGAACAAGTTCGGCATCGCCATCGACGAGGCCGAGGCGGTCTACGCCCGCGCCGCCGAGCTTGACCACCTGGAGGTGATCGGCGTCGACTGCCACATCGGCTCGCAGTTGACCCAGCTGGAGCCCTTCCTCGACGCCCTCGAGCGCCTGCTCGGGCTGGTCGACCGCCTGGCCGGCAAAGGCATCGGCATTCGCCACCTGGACCTCGGTGGTGGCCTCGGGGTGCGCTACCGCGACGAACAGCCGCCGCTGGCCGGCGACTACATCCGCGCCATCCGCGAGCGCCTGCACGGCCGCGACCTGACCCTGGTGTTCGAGCCGGGCCGGTCCATCGTCGCCAACGCCGGCGTGCTGCTGACCCGTGTCGAGTACCTCAAGCACACCGAGCACAAGGATTTCGCCATCGTCGACGCGGCGATGAACGACCTGATCCGCCCGGCTCTCTACCAGGCCTGGATGGACGTGCAGGCGGTACGCCCGCGCGACGCCGCGCCGCGCCGCTACGACCTGGTCGGGCCGATCTGCGAGACCGGTGACTTCCTCGCCAAGGATCGCGACCTGGCGCTCGCCGAAGGCGACCTCCTGGCGGTGCGCTCGGCCGGCGCCTACGGCTTCGTCATGAGCTCGAACTACAACACCCGCGGCCGCGCCGCCGAGGTGCTGGTGGATGGCGAGCAGACCCACGAGGTCCGTCGCCGCGAGACCGTCCAAGAGCTCTACGCCGGCGAAAGCCTGCTGCCGCAGTGA
Protein Properties
Protein Residues: 415
Protein Molecular Weight: 45.5 kDa
Protein Theoretical pI: 5.35
Hydropathicity (GRAVY score): -0.12
Charge at pH 7 (predicted): -10.45
Protein Sequence: 
>PA5277
MDTFSYRDAELFAEGVALSRIAERFGTPTYVYSRAHIEAQYRAYADALAGMPHLVCFAVKANSNLGVLNVLARLGAGFDIVSRGELERVLAAGGDPAKVVFSGVGKTRDDMRRALEVGVHCFNVESGEELERLQRVAAELGVKAPVSLRVNPDVDAQTHPYISTGLKENKFGIAIDEAEAVYARAAELDHLEVIGVDCHIGSQLTQLEPFLDALERLLGLVDRLAGKGIGIRHLDLGGGLGVRYRDEQPPLAGDYIRAIRERLHGRDLTLVFEPGRSIVANAGVLLTRVEYLKHTEHKDFAIVDAAMNDLIRPALYQAWMDVQAVRPRDAAPRRYDLVGPICETGDFLAKDRDLALAEGDLLAVRSAGAYGFVMSSNYNTRGRAAEVLVDGEQTHEVRRRETVQELYAGESLLPQ
References
External Links:
Resource Link
Genome ID: PA5277
Entrez Gene ID: 877749
NCBI Protein ID: 15600470
General Reference: PaperBLAST - Find papers about PA5277 and its homologs