Probable ubiquinone biosynthesis protein ubiB (PA5065)

Identification
Name: Probable ubiquinone biosynthesis protein ubiB
Synonyms: Not Available
Gene Name: ubiB
Enzyme Class: Not Available
Biological Properties
General Function: Involved in transferase activity, transferring phosphorus-containing groups
Specific Function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis. Specific for aerobically grown log-phase cells
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways: Not Available
KEGG Reactions:
Thumb+Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
2-Octaprenylphenol + Oxygen + NADPH + Hydrogen ion ↔ 2-Octaprenyl-6-hydroxyphenol + NADP + Water
ReactionCard
2-Polyprenylphenol+Thumb+Thumb ↔ 2-Polyprenyl-6-hydroxyphenol+Thumb+Thumb
2-Polyprenylphenol + Oxygen + NADPH ↔ 2-Polyprenyl-6-hydroxyphenol + NADP + Water
ReactionCard
Thumb+Thumb+Thumb+Thumb → Thumb+Thumb+Thumb
2-Octaprenylphenol + Oxygen + NADPH + Hydrogen ion → 2-Octaprenyl-6-hydroxyphenol + Water + NADP
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+Thumb+Thumb → Thumb+Thumb+Thumb
2-Octaprenylphenol + Oxygen + NADPH + Hydrogen ion → 2-Octaprenyl-6-hydroxyphenol + Water + NADP
ReactionCard
Complex Reactions:
Thumb+0.5 Thumb → Thumb
2-Octaprenylphenol + 0.5 Oxygen → 2-Octaprenyl-6-hydroxyphenol
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0006192-Octaprenyl-6-hydroxyphenolMetaboCard
PAMDB0006222-OctaprenylphenolMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000089NADPMetaboCard
PAMDB000615NADPHMetaboCard
PAMDB000624OxygenMetaboCard
PAMDB001302Ubiquinone-0MetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Process
cellular metabolic process
coenzyme metabolic process
cofactor metabolic process
metabolic process
oxidoreduction coenzyme metabolic process
ubiquinone biosynthetic process
ubiquinone metabolic process
Gene Properties
Locus tag: PA5065
Strand: +
Entrez Gene ID: 878018
Accession: NP_253752.1
GI: 15600258
Sequence start: 5704077
Sequence End: 5705678
Sequence Length: 1601
Gene Sequence: 
>PA5065
ATGAAGCTCCTCGCTGTCCGCCGCCTCCTGCGCATCCAGCGCGTCGTCATCCGCTACCGCCTGGACGACCTGATCCTCGAACTGCCGATGCTGCCCTGGTGGCTGCGCCTGCTCGGTGCCACCCTGCCCTGGCGCTGGCTGCCGCGGCGCAAGCTGGAACTGACCCGCGGCGCGCGCCTGCGCCTGGCACTGCAGGACCTCGGACCGATCTTCATCAAGTTCGGCCAGATTCTCTCCACCCGCCGCGACCTGCTGCCCGACGACATCGCCAACGAACTGGCCTGGCTGCAGGACAAGGTGCCGCCCTTCCCGCCGGAGCTGGCGGTCAAGCGCATCGAGGAACAGCTGGGCGCGAAGATCGAACAGGTCTTCGCCCGCTTCGAACGCGAACCGCTGGCCTCCGCCTCGGTGGCCCAGGTCCACGCCGCGCGCCTGAAGAGCGGCGAGGAAGTGGTGGTGAAGGTGATCCGGCCGAACCTGGAACCGGTGATCCGCTCCGACATCGCCTGGCTGTTCATCCTCGCCCGCCTCGCCGAGCGGGTCTCCAGCGAGGCGCGGCGCCTGCACCCGGTGGAAGTGGTCAGCGACTACGAGAAGACCATCGTCGACGAACTCGACCTGCTCCGCGAGGCGGCCAACGCCTCGCAGCTGCGACGCAACTTCGAAGGCTCGCCGCTGCTCTACGTGCCACAGGTCTACTGGGACTGGTGCCGGCCCAAGGTGCTGGTGATGGAGCGCATCTACGGCATCCCGGTGACCGACCTGGAAACCCTGCGCGACCAGCGCACCGACTTCAAGGCACTGGCCGAGCGCGGCGTGGAGATCTTCTTCACCCAGGTGTTCCGCGACAGCTTTTTCCATGCCGACATGCACCCCGGCAACATCTTCGTCAGCACCCGCGCGCCCTGGAGCCCGCAATACATCGCGGTGGACTGCGGCATCGTCGGCAGCCTGACCGACGAGGACCAGGACTACCTGGCGCGCAACCTGATCGCCTTCTTCAAGCGCGACTACCGCAAGGTCGCCCAACTGCATATCGACTCCGGCTGGGTACCGGCGGAAACCAAGGTCAACGACTTCGAGGCGGCGATCCGCACCGTCTGCGAACCGATCTTCGAGAAGCCGCTGAAGGACATCTCCTTCGGCCAGGTCCTGCTGCGCCTGTTCCAGACCGCGCGCCGTTTCAACATGGAGATCCAGCCGCAACTGGTGTTGCTGCAGAAGACCCTGCTGAACATCGAAGGCCTCGGCCGCCAGCTCTACCCGGAACTCGACCTGTGGGCCACCGCCCAGCCGTTCCTGGAGCGCTGGATGCGCGAACGGGTCAGCCCGAAGCAGTTGCTGCGCAATTTCCAGCAACAGGTCGAGCAGGTGCCGCACCTGTCGCAAATGGCCCGCGACACCCTCGAACGCCTGTCACAACCGCACGCCCACAATGCGCCGCCGCCGGAGTGGAAAGGTTCCCGCCACGACTGGCTCGGGCGCCTGGTGGGCGCGGTGCTGCTGGTCGGCGCCGCCGAGGTCGGCCTGGGCCAGCAGCTGGAAGCCTGGCCGGCGTGGGTGATGCTGGCCGGCGGGGTATTCCTGATCCTGCGCCGCTAG
Protein Properties
Protein Residues: 533
Protein Molecular Weight: 61.7 kDa
Protein Theoretical pI: 9.44
Hydropathicity (GRAVY score): -0.129
Charge at pH 7 (predicted): 8.11
Protein Sequence: 
>PA5065
MKLLAVRRLLRIQRVVIRYRLDDLILELPMLPWWLRLLGATLPWRWLPRRKLELTRGARLRLALQDLGPIFIKFGQILSTRRDLLPDDIANELAWLQDKVPPFPPELAVKRIEEQLGAKIEQVFARFEREPLASASVAQVHAARLKSGEEVVVKVIRPNLEPVIRSDIAWLFILARLAERVSSEARRLHPVEVVSDYEKTIVDELDLLREAANASQLRRNFEGSPLLYVPQVYWDWCRPKVLVMERIYGIPVTDLETLRDQRTDFKALAERGVEIFFTQVFRDSFFHADMHPGNIFVSTRAPWSPQYIAVDCGIVGSLTDEDQDYLARNLIAFFKRDYRKVAQLHIDSGWVPAETKVNDFEAAIRTVCEPIFEKPLKDISFGQVLLRLFQTARRFNMEIQPQLVLLQKTLLNIEGLGRQLYPELDLWATAQPFLERWMRERVSPKQLLRNFQQQVEQVPHLSQMARDTLERLSQPHAHNAPPPEWKGSRHDWLGRLVGAVLLVGAAEVGLGQQLEAWPAWVMLAGGVFLILRR
References
External Links:
Resource Link
Genome ID: PA5065
Entrez Gene ID: 878018
NCBI Protein ID: 15600258
General Reference: PaperBLAST - Find papers about PA5065 and its homologs