Glucose-6-phosphate isomerase (PA4732)

Identification
Name: Glucose-6-phosphate isomerase
Synonyms:
  • GPI
  • Phosphoglucose isomerase
  • PGI
  • Phosphohexose isomerase
  • PHI
Gene Name: pgi
Enzyme Class:
Biological Properties
General Function: Involved in glucose-6-phosphate isomerase activity
Specific Function: D-glucose 6-phosphate = D-fructose 6- phosphate
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb
Glucose 6-phosphate + Alpha-D-glucose 6-phosphate ↔ beta-D-Glucose 6-phosphate
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Thumb ↔ Thumb
Glucose 6-phosphate ↔ beta-D-Fructose 6-phosphate
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Thumb ↔ Thumb
beta-D-Glucose 6-phosphate ↔ beta-D-Fructose 6-phosphate
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Thumb ↔ Thumb
Glucose 6-phosphate ↔ Fructose 6-phosphate
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SMPDB Reactions:
Thumb → Fructose 6-phosphate+Thumb
beta-D-Glucose 6-phosphate → Fructose 6-phosphate + Fructose 6-phosphate
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Thumb → β-D-glucose 6-phosphate
D-tagatofuranose 6-phosphate → β-D-glucose 6-phosphate
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β-D-glucose 6-phosphate+Thumb ↔ Thumb
β-D-glucose 6-phosphate + β-D-glucose 6-phosphate ↔ D-tagatofuranose 6-phosphate
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Thumb → Thumb
D-tagatofuranose 6-phosphate → beta-D-Glucose 6-phosphate
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Thumb → Thumb
beta-D-Glucose 6-phosphate → beta-D-Fructose 6-phosphate
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β-D-glucose 6-phosphate ↔ Thumb
β-D-glucose 6-phosphate ↔ D-tagatofuranose 6-phosphate
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PseudoCyc/BioCyc Reactions:
Thumb ↔ Thumb
Glucose 6-phosphate ↔ Fructose 6-phosphate
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Complex Reactions:
Thumb → Thumb
Glucose 6-phosphate → Fructose 6-phosphate
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Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB006323 β-D-glucose 6-phosphateMetaboCard
PAMDB003454Alpha-D-glucose 6-phosphateMetaboCard
PAMDB000547beta-D-Fructose 6-phosphateMetaboCard
PAMDB000506beta-D-Glucose 6-phosphateMetaboCard
PAMDB006322D-tagatofuranose 6-phosphateMetaboCard
PAMDB000047Fructose 6-phosphateMetaboCard
PAMDB000372Glucose 6-phosphateMetaboCard
GO Classification:
Function
catalytic activity
glucose-6-phosphate isomerase activity
intramolecular oxidoreductase activity
intramolecular oxidoreductase activity, interconverting aldoses and ketoses
isomerase activity
Process
alcohol metabolic process
gluconeogenesis
glucose catabolic process
glucose metabolic process
glycolysis
hexose metabolic process
metabolic process
monosaccharide metabolic process
small molecule metabolic process
Gene Properties
Locus tag: PA4732
Strand: +
Entrez Gene ID: 881638
Accession: NP_253420.1
GI: 15599926
Sequence start: 5313676
Sequence End: 5315340
Sequence Length: 1664
Gene Sequence: 
>PA4732
ATGAAGCACCACCTCACTCCGCTGGATGCCACGCAACTCGACAGTTGGCGCGCCCTGGCCGCCCATCGCCAGGAACTGCAGGACTTCAGGATGCGCCAGGCGTTCATCGACGATCCGGAGCGCTTCAAGCGGTTTTCCTTCAGCGCCTGTGGGCTGTTCCTCGACTTCTCGAAGAACCTGATTCGCCAGGACACCATCGACCTGCTGGTGAAGCTGGCCGAGGAAGCACGGCTGAGCGACGCGATCCGGGCGATGTTCGACGGCGAGGCGATCAATGCCTCCGAGCGCCGGCCGGTACTGCATACCGCGCTGCGTCGACCGATCGGCGACAAGGTGCTGGTCGATGGCGTCGACGTGATGCCGGAAGTCCACCGCGTCCTGCACCAGATGACCGAGCTGGTGGGCTACGTGCACAACGGCCTGTGGCGCGGCTATACCGAAAAGCCGATCACCGACGTGGTGAACATCGGCATCGGCGGCTCCTTCCTCGGCCCGCAACTGGTATCCGAAGCCTTGCTGCCATTCGCCCAGAAAGGCGTGCGCTGCCACTACCTGGCGAACATCGACGGTAGCGAGTTCCATGAACTGGCCAGCCGCCTGAACGCCGAGACCACCCTGTTCATCGTTTCCTCCAAGTCCTTCGGGACCCTGGAAACCCTGAAGAACGCCCAGGCCGCACGCGCCTGGTACCTGGCCCAGGGCGGCACCGAGGAAGAGCTTTACCGCCATTTCATCGCCGTCTCCAGCAACAAGGAGGCCGCGATCGCCTTTGGCATCCGCGAGGAAAACATCTTCCCCATGTGGGACTGGGTCGGCGGCCGCTACTCGCTGTGGTCGGCCATCGGCCTGCCGATCGCCATGTCCATCGGCATCTCCAACTTCAAGGAGTTGCTGTCCGGTGCCTACAACATGGACCAGCACTTCCAGACCGCGCCGTTCGAACGCAACATCCCGGTGCTGCTCGGCCTGCTCGGCGTCTGGTACGGCGACTTCTGGGGCGCGAACAGCCACGCGATCCTGCCCTACGACTACTATCTGCGGAATATCACCGACCACCTGCAACAACTGGACATGGAATCCAACGGCAAGAGCGTGCGCCAGGACGGCACGCCGGTCACCAGCGGCACCGGGCCGGTGATCTGGGGTGGTGTCGGCTGCAACGGCCAGCACGCCTACCATCAGTTGCTGCACCAAGGCACCCAGTTGATCCCGGCGGACTTCATCGTCCCGGTGAGCAGCTACAACCCGGTGGCCGACCATCACCAGTGGCTGTACGCCAACTGCCTGTCGCAGAGCCAGGCGCTGATGCTCGGCAAGAGCCGCGAGGAGGCCGAGGCCGAACTGCGCGCCAAGGGCCTGCCGGAAGCCGAAGTGCAGCGCCTGGCGCCGCACAAGGTGATTCCGGGCAACCGACCGAGCAACACCCTGGTGGTCGAGCGCATCAGCGCCCGCCGCCTCGGCGCGCTGATCGCCATGTACGAGCACAAGGTCTACGTACAGAGCATCCTCTGGGGCATCAACGCCTTCGACCAATGGGGCGTGGAGCTTGGCAAGGAACTCGGCAAGGGTGTCTATTCGCGCCTGGTCGGCAGCGAGGAAACCCCGGCCGAGGACGCCTCGACCCAAGGCCTGATCGACTTCTTCCGCGGCCGCCATCGCGGCTGA
Protein Properties
Protein Residues: 554
Protein Molecular Weight: 61.9 kDa
Protein Theoretical pI: 6.55
Hydropathicity (GRAVY score): -0.2
Charge at pH 7 (predicted): -5.05
Protein Sequence: 
>PA4732
MKHHLTPLDATQLDSWRALAAHRQELQDFRMRQAFIDDPERFKRFSFSACGLFLDFSKNLIRQDTIDLLVKLAEEARLSDAIRAMFDGEAINASERRPVLHTALRRPIGDKVLVDGVDVMPEVHRVLHQMTELVGYVHNGLWRGYTEKPITDVVNIGIGGSFLGPQLVSEALLPFAQKGVRCHYLANIDGSEFHELASRLNAETTLFIVSSKSFGTLETLKNAQAARAWYLAQGGTEEELYRHFIAVSSNKEAAIAFGIREENIFPMWDWVGGRYSLWSAIGLPIAMSIGISNFKELLSGAYNMDQHFQTAPFERNIPVLLGLLGVWYGDFWGANSHAILPYDYYLRNITDHLQQLDMESNGKSVRQDGTPVTSGTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVPVSSYNPVADHHQWLYANCLSQSQALMLGKSREEAEAELRAKGLPEAEVQRLAPHKVIPGNRPSNTLVVERISARRLGALIAMYEHKVYVQSILWGINAFDQWGVELGKELGKGVYSRLVGSEETPAEDASTQGLIDFFRGRHRG
References
External Links:
Resource Link
Genome ID: PA4732
Entrez Gene ID: 881638
NCBI Protein ID: 15599926
General Reference: PaperBLAST - Find papers about PA4732 and its homologs