Alpha-D-glucose 6-phosphate (PAMDB003454)

IdentificationTaxonomyPhysical PropertiesBiological PropertiesSpectraConcentrationsLinksReferencesEnzymes Transporters
Proteins (3280)
Record Information
Version 1.0
Update Date 1/22/2018 11:54:54 AM
Metabolite IDPAMDB003454
Identification
Name: Alpha-D-glucose 6-phosphate
Description:A D-glucopyranose 6-phosphate where α-D-glucose is the sugar component
Structure
Thumb
🔍MOLSDFPDBSMILESInChIView Structure
Synonyms:
  • 6-O-phosphono-a-D-Glucopyranose
  • 6-O-phosphono-alpha-D-Glucopyranose
  • 6-O-phosphono-α-D-glucopyranose
  • a-D-Glucose 6-phosphate
  • a-D-Glucose 6-phosphoric acid
  • a-D-GLUCOSE-6-phosphate
  • a-D-GLUCOSE-6-phosphoric acid
  • alpha-D-Glucose 6-phosphoric acid
  • ALPHA-D-GLUCOSE-6-phosphATE
  • alpha-D-GLUCOSE-6-phosphoric acid
  • α-D-glucose 6-phosphate
  • α-D-Glucose 6-phosphate
  • α-D-glucose 6-phosphoric acid
  • α-D-Glucose 6-phosphoric acid
  • α-D-glucose-6-phosphate
  • α-D-glucose-6-phosphoric acid
Chemical Formula: C6H13O9P
Average Molecular Weight: 260.1358
Monoisotopic Molecular Weight: 260.029718526
InChI Key: NBSCHQHZLSJFNQ-DVKNGEFBSA-N
InChI:InChI=1S/C6H13O9P/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5-,6+/m1/s1
CAS number: Not Available
IUPAC Name:{[(2R,3S,4S,5R,6S)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid
Traditional IUPAC Name: α-D-glucose 6-phosphate
SMILES:O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O
Chemical Taxonomy
Taxonomy DescriptionThis compound belongs to the class of organic compounds known as monosaccharide phosphates. These are monosaccharides comprising a phosphated group linked to the carbohydrate unit.
Kingdom Organic compounds
Super ClassOrganooxygen compounds
Class Carbohydrates and carbohydrate conjugates
Sub ClassMonosaccharides
Direct Parent Monosaccharide phosphates
Alternative Parents
Substituents
  • Monosaccharide phosphate
  • Monoalkyl phosphate
  • Alkyl phosphate
  • Phosphoric acid ester
  • Oxane
  • Organic phosphoric acid derivative
  • Organic phosphate
  • Secondary alcohol
  • Polyol
  • Hemiacetal
  • 1,2-diol
  • Oxacycle
  • Organoheterocyclic compound
  • Hydrocarbon derivative
  • Alcohol
  • Aliphatic heteromonocyclic compound
Molecular Framework Aliphatic heteromonocyclic compounds
External Descriptors
Physical Properties
State: Not Available
Charge:-2
Melting point: Not Available
Experimental Properties:
PropertyValueSource
Predicted Properties
PropertyValueSource
Water Solubility31.4 mg/mLALOGPS
logP-2.1ALOGPS
logP-3.1ChemAxon
logS-0.92ALOGPS
pKa (Strongest Acidic)1.22ChemAxon
pKa (Strongest Basic)-3.6ChemAxon
Physiological Charge-2ChemAxon
Hydrogen Acceptor Count8ChemAxon
Hydrogen Donor Count6ChemAxon
Polar Surface Area156.91 Å2ChemAxon
Rotatable Bond Count3ChemAxon
Refractivity46.8 m3·mol-1ChemAxon
Polarizability20.56 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Biological Properties
Cellular Locations: Cytoplasm
Reactions:
Glucose 6-phosphate + Alpha-D-glucose 6-phosphate <> beta-D-Glucose 6-phosphate
Alpha-D-glucose 6-phosphate > beta-D-Glucose 6-phosphate
Alpha-D-glucose 6-phosphate > α-D-glucose 1-phosphate
Alpha-D-glucose 6-phosphate <> Alpha-D-glucose 1-phosphate
UDP-Glucose + Alpha-D-glucose 6-phosphate > Uridine 5'-diphosphate + Trehalose 6-phosphate + Hydrogen ion + Uridine 5'-diphosphate
Pathways:
Spectra
Spectra:
Spectrum TypeDescriptionSplash Key
GC-MSGC-MS Spectrum - GC-MSNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-03di-0490000000-1a5b3049c27a2a9b8996View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-03dm-4940000000-cbc695bef22278b36879View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0uka-8900000000-320e52be29673422365eView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-0a6r-6290000000-e76ad7d6142e19f5a9c2View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-004i-9000000000-e27be76de6d71ada7083View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-004i-9000000000-9540d84c7e74555e7a01View in MoNA
References
References: Not Available
Synthesis Reference: Not Available
Material Safety Data Sheet (MSDS) Not Available
External Links:
ResourceLink
CHEBI ID17665
HMDB IDNot Available
Pubchem Compound ID439284
Kegg IDC00668
ChemSpider ID388417
Wikipedia IDNot Available
BioCyc IDNot Available
Ligand ExpoG6P

Enzymes

Protein Details
• Glucose-6-phosphate isomerase
General function:
Involved in glucose-6-phosphate isomerase activity
Specific function:
D-glucose 6-phosphate = D-fructose 6- phosphate
Gene Name:
pgi
Locus Tag:
PA4732
Molecular weight:
61.9 kDa
Reactions
D-glucose 6-phosphate = D-fructose 6-phosphate.
Protein Details
• Glucokinase
General function:
Involved in glucokinase activity
Specific function:
Not highly important in Pseudomonas aeruginosa as glucose is transported into the cell by the PTS system already as glucose 6-phosphate
Gene Name:
glk
Locus Tag:
PA3193
Molecular weight:
34.6 kDa
Reactions
ATP + D-glucose = ADP + D-glucose 6-phosphate.
Protein Details
• Phosphoglucomutase
General function:
Involved in intramolecular transferase activity, phosphotransferases
Specific function:
This enzyme participates in both the breakdown and synthesis of glucose
Gene Name:
pgm
Locus Tag:
PA5131
Molecular weight:
55.6 kDa
Reactions
Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.