Aspartate 1-decarboxylase (PA4731)

Identification
Name: Aspartate 1-decarboxylase
Synonyms:
  • Aspartate alpha-decarboxylase
  • Aspartate 1-decarboxylase beta chain
  • Aspartate 1-decarboxylase alpha chain
Gene Name: panD
Enzyme Class:
Biological Properties
General Function: Involved in aspartate 1-decarboxylase activity
Specific Function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb
L-Aspartic acid + Hydrogen ion ↔ beta-Alanine + Carbon dioxide
ReactionCard
Thumb ↔ Thumb+Thumb
L-Aspartic acid ↔ beta-Alanine + Carbon dioxide
ReactionCard
SMPDB Reactions:
L-Aspartic acid+Thumb+Thumb ? Thumb+Thumb
L-Aspartic acid + Hydrogen ion + L-Aspartic acid ? Carbon dioxide + beta-Alanine
ReactionCard
L-Aspartic acid+Thumb+Thumb → Thumb+Thumb
L-Aspartic acid + Hydrogen ion + L-Aspartic acid → Carbon dioxide + beta-Alanine
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb
L-Aspartic acid + Hydrogen ion ↔ beta-Alanine + Carbon dioxide
ReactionCard
Complex Reactions:
Thumb → Thumb+Thumb
L-Aspartic acid → beta-Alanine + Carbon dioxide
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000019beta-AlanineMetaboCard
PAMDB000568Carbon dioxideMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000080L-Aspartic acidMetaboCard
GO Classification:
Function
aspartate 1-decarboxylase activity
binding
carbon-carbon lyase activity
carboxy-lyase activity
catalytic activity
lyase activity
Process
alanine biosynthetic process
alanine metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
cellular metabolic process
metabolic process
pyruvate family amino acid metabolic process
Gene Properties
Locus tag: PA4731
Strand: +
Entrez Gene ID: 881637
Accession: NP_253419.1
GI: 15599925
Sequence start: 5313206
Sequence End: 5313586
Sequence Length: 380
Gene Sequence: 
>PA4731
ATGCACGCCATAATGCTCAAAGCCAAGTTGCATCGCGCCGAAGTCACCCATGCCGTCCTCGACTACGAAGGCTCCTGCGCCATCGACGGCGATTGGCTGGACCTCTCCGGAATCCGCGAGTACGAACAGATCCAGATCTACAACATCGACAACGGCGAGCGCTTCACCACCTATGCGATCCGCGCCGAGAACGGCTCGAAGATGATCTCGGTGAACGGCGCCGCGGCACACAAGGCCAAGGTCGGCGACCGCGTGATCATCTGCGCCTACGCACACTACAGCGAAGCCGAACTGGCCAGCCACAAGCCGCGCATGCTGTACATGGCGCCGGGCAACCAGCTCAGCCATACCAGCGAGGCGATTCCGATACAGGTCGCCTGA
Protein Properties
Protein Residues: 126
Protein Molecular Weight: 13.9 kDa
Protein Theoretical pI: 6.62
Hydropathicity (GRAVY score): -0.196
Charge at pH 7 (predicted): -1.39
Protein Sequence: 
>PA4731
MHAIMLKAKLHRAEVTHAVLDYEGSCAIDGDWLDLSGIREYEQIQIYNIDNGERFTTYAIRAENGSKMISVNGAAAHKAKVGDRVIICAYAHYSEAELASHKPRMLYMAPGNQLSHTSEAIPIQVA
References
External Links:
Resource Link
Genome ID: PA4731
Entrez Gene ID: 881637
NCBI Protein ID: 15599925
General Reference: PaperBLAST - Find papers about PA4731 and its homologs