Acetolactate synthase isozyme 3 small subunit (PA4695)

Identification
Name: Acetolactate synthase isozyme 3 small subunit
Synonyms:
  • ALS-III
  • Acetohydroxy-acid synthase III small subunit
  • AHAS-III
Gene Name: ilvH
Enzyme Class:
Biological Properties
General Function: Involved in acetolactate synthase activity
Specific Function: 2 pyruvate = 2-acetolactate + CO(2)
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb
2-Ketobutyric acid + Hydrogen ion + Pyruvic acid → 2-Aceto-2-hydroxy-butyrate + Carbon dioxide
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Thumb+2 Thumb → Thumb+Thumb
Hydrogen ion + 2 Pyruvic acid → (S)-2-Acetolactate + Carbon dioxide
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Thumb+Thumb ↔ 2 Thumb
2-Acetolactate + Carbon dioxide ↔ 2 Pyruvic acid
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Thumb+Thumb ↔ 2 Thumb
(S)-2-Acetolactate + Carbon dioxide ↔ 2 Pyruvic acid
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SMPDB Reactions:
2 Thumb+Thumb → Thumb+Thumb
2 Pyruvic acid + Hydrogen ion → Carbon dioxide + (S)-2-Acetolactate
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Thumb+Thumb+Thumb → Thumb+Thumb
2-Ketobutyric acid + Hydrogen ion + Pyruvic acid → Carbon dioxide + 2-Aceto-2-hydroxy-butyrate
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Thumb → Thumb+Thumb
Pyruvic acid → Carbon dioxide + 2-Acetolactate
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PseudoCyc/BioCyc Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb
2-Ketobutyric acid + Hydrogen ion + Pyruvic acid → 2-Aceto-2-hydroxy-butyrate + Carbon dioxide
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Complex Reactions:
2 Thumb → Thumb+Thumb
2 Pyruvic acid → 2-Acetolactate + Carbon dioxide
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Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000697(S)-2-AcetolactateMetaboCard
PAMDB0005492-Aceto-2-hydroxy-butyrateMetaboCard
PAMDB0005502-AcetolactateMetaboCard
PAMDB0000012-Ketobutyric acidMetaboCard
PAMDB000568Carbon dioxideMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000102Pyruvic acidMetaboCard
PAMDB000361Thiamine pyrophosphateMetaboCard
GO Classification:
Function
acetolactate synthase activity
amino acid binding
binding
carboxylic acid binding
catalytic activity
transferase activity
transferase activity, transferring aldehyde or ketonic groups
Process
branched chain family amino acid biosynthetic process
cellular amino acid and derivative metabolic process
cellular amino acid biosynthetic process
cellular amino acid metabolic process
cellular metabolic process
metabolic process
Gene Properties
Locus tag: PA4695
Strand: -
Entrez Gene ID: 881490
Accession: NP_253383.1
GI: 15599889
Sequence start: 5273514
Sequence End: 5274005
Sequence Length: 491
Gene Sequence: 
>PA4695
ATGCGACACATCATTTCCCTGCTGCTGGAAAACGAGCCAGGCGCATTGTCCCGCGTGGTCGGCCTGTTCTCCCAACGCAACTACAACATCGAAAGCCTGACCGTGGCGCCGACCGAGGACCCGACCCTGTCGCGTCTGACGCTGACCACCGTGGGGCACGATGAGGTGATCGAGCAGATCACCAAGAACCTCAACAAGCTGATCGAAGTGGTCAAGCTGGTGGATCTGTCGGAAAGCGCCCATATCGAGCGCGAGCTGATGCTGGTGAAGGTCAAGGCCACGGGCGCCCAGCGCGCCGAGGTCAAGCGCACCACCGATATCTTCCGTGGGCAGATCGTCGACGTCACCAGTAGCGTCTATACCGTGCAACTGGCGGGTACCAGCGACAAACTGGACAGCTTCATCCAGGCCATCGGCACTGCGTCGATCCTGGAAGTGGTCCGCAGTGGCGTCACTGGCATCGCCCGTGGCGACAAGACTCTGAGCATCTGA
Protein Properties
Protein Residues: 163
Protein Molecular Weight: 17.8 kDa
Protein Theoretical pI: 6.27
Hydropathicity (GRAVY score): 0.079
Charge at pH 7 (predicted): -1.28
Protein Sequence: 
>PA4695
MRHIISLLLENEPGALSRVVGLFSQRNYNIESLTVAPTEDPTLSRLTLTTVGHDEVIEQITKNLNKLIEVVKLVDLSESAHIERELMLVKVKATGAQRAEVKRTTDIFRGQIVDVTSSVYTVQLAGTSDKLDSFIQAIGTASILEVVRSGVTGIARGDKTLSI
References
External Links:
Resource Link
Genome ID: PA4695
Entrez Gene ID: 881490
NCBI Protein ID: 15599889
General Reference: PaperBLAST - Find papers about PA4695 and its homologs