Identification
Name: Riboflavin biosynthesis protein ribD
Synonyms:
  • Diaminohydroxyphosphoribosylaminopyrimidine deaminase
  • DRAP deaminase
  • Riboflavin-specific deaminase
  • 5-amino-6-(5-phosphoribosylamino)uracil reductase
  • HTP reductase
Gene Name: ribD
Enzyme Class:
Biological Properties
General Function: Involved in zinc ion binding
Specific Function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb+Thumb
Thumb+Thumb+ThumbThumb+Thumb
SMPDB Reactions:
Thumb+Thumb+ThumbThumb+Thumb
Thumb+Thumb+ThumbThumb+Thumb
Thumb+Thumb+NADPH+ThumbThumb+5-Amino-6-(5'-phosphoribitylamino)uracil+Thumb
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb+Thumb
Thumb+Thumb+ThumbThumb+Thumb
Complex Reactions:
Thumb+Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
Thumb+Thumb5-amino-6-(5-phospho-D-ribosylamino)uracil+Thumb
5-Amino-6-(5'-phosphoribitylamino)uracil + NADP → 5-amino-6-(5-phospho-D-ribosylamino)uracil + NADPH
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0009072,5-Diamino-6-(5'-phosphoribosylamino)-4-pyrimidineoneMetaboCard
PAMDB0005842,5-Diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidineMetaboCard
PAMDB0015865-Amino-6-(5'-phosphoribitylamino)uracilMetaboCard
PAMDB0009475-Amino-6-(5'-phosphoribosylamino)uracilMetaboCard
PAMDB000017AmmoniaMetaboCard
PAMDB001595AmmoniumMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000089NADPMetaboCard
PAMDB000615NADPHMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
5-amino-6-(5-phosphoribosylamino)uracil reductase activity
binding
catalytic activity
cation binding
diaminohydroxyphosphoribosylaminopyrimidine deaminase activity
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
ion binding
metal ion binding
NADP or NADPH binding
nucleotide binding
oxidoreductase activity
oxidoreductase activity, acting on CH-OH group of donors
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
transition metal ion binding
zinc ion binding
Process
metabolic process
nitrogen compound metabolic process
oxidation reduction
riboflavin biosynthetic process
riboflavin metabolic process
Gene Properties
Locus tag: PA4056
Strand: -
Entrez Gene ID: 879079
Accession: NP_252745.1
GI: 15599251
Sequence start: 4536921
Sequence End: 4538042
Sequence Length: 1121
Gene Sequence:
>PA4056
ATGAACGCCGCCGACCCGCTGTACATGGCCCGCGCCCTGGAACTGGCGCGCCAGGGGCTGTACTCCACCCAGCCGAATCCGCGCGTCGGCTGCGTGCTGGTCAAGGACGGCCAGGTGGTCGGCGAGGGCTGGCACGTCCGCGCCGGCGAGCCGCACGCCGAGGTCCATGCCCTGCGCCAGGCCGGCGAGAATGCACGCGGCGCCACCGCCTACGTGACCCTCGAGCCCTGCAGCCACTTCGGCCGCACCCCGCCGTGCGCCGATGCGCTGGTGGGCGCCGGGGTGGCGCGGGTGGTCGCGGCGATGCAGGATCCCAACCCCGAGGTCGCCGGTCGCGGCCTGCTGCGTCTGATGCAGGCCGGCATCGCGGTGCAGAGCGGCGTCCTCGAAGCCGAGGCGCGGGAACTCAACATCGGTTTCATCAAGCGCATGGAACATGGCCTGCCGTTCGTCCGGGTCAAGCTGGCGATGAGCCTGGACGGGCGCACCGCCATGGCCAGCGGGGAAAGCCAGTGGATCACCGGGCCCTCCGCGCGTTCGGCGGTGCAGCGCTTGCGCGCTCGCTCCAGCGTGGTGTTGTCCGGCGCCGATACGCTGCTGGCGGACGATGCGCGGCTCAACGTACGCCCCGACGAACTGGGCCTGAACGCCGAGCTTACCGCGCTCGCCGCGGCTCGCCAGCCGTTGCGGGTGCTGGTCGACGGGCGCCTGCGGGTGCCGCTGGAGTCGGCGTTCTACCAGGCCGGTCCGGCGCTGGTGGCGACCTGCGCCGCCGCCTCGGCGCGCGAACGCTTCCAGGACGCCGGCCACGAACTGCTGGCGCTGCCCTCCGCCGAGGGCCACGTCGATTTGCACAAGCTGCTCCTGGAACTGGCGGCGCGCGGCGCCAACGAAGTGCTGGTGGAGGCCGGCCCGCGTCTGGCCGGCGCCTTCGCCCGGCTGGGGCTGGTGGATGAGTACCGGCTGTTCGTCGCGCCGAAGTTCCTCGGCTCCAGCGCCCGTCCTTTGCTCGATTGGCCGCTGGCGCGGATGGCCGATGCGGCGCAGTTGCGGATCGACGACATCCGCGCGGTGGGCGACGACTGGCTGGTCACCGCGCGGCCCCATCTGCGGGACGCCTGA
Protein Properties
Protein Residues: 373
Protein Molecular Weight: 39.8 kDa
Protein Theoretical pI: 7.29
Hydropathicity (GRAVY score): 0.019
Charge at pH 7 (predicted): 1.05
Protein Sequence:
>PA4056
MNAADPLYMARALELARQGLYSTQPNPRVGCVLVKDGQVVGEGWHVRAGEPHAEVHALRQAGENARGATAYVTLEPCSHFGRTPPCADALVGAGVARVVAAMQDPNPEVAGRGLLRLMQAGIAVQSGVLEAEARELNIGFIKRMEHGLPFVRVKLAMSLDGRTAMASGESQWITGPSARSAVQRLRARSSVVLSGADTLLADDARLNVRPDELGLNAELTALAAARQPLRVLVDGRLRVPLESAFYQAGPALVATCAAASARERFQDAGHELLALPSAEGHVDLHKLLLELAARGANEVLVEAGPRLAGAFARLGLVDEYRLFVAPKFLGSSARPLLDWPLARMADAAQLRIDDIRAVGDDWLVTARPHLRDA
References
External Links:
Resource Link
Genome ID: PA4056
Entrez Gene ID: 879079
NCBI Protein ID: 15599251
General Reference: PaperBLAST - Find papers about PA4056 and its homologs